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BMP-6 elisa kit :: Mouse BMP-6 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2513110 (SPECIAL PROMOTIONAL PRICING for a limited time)
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $310 +1 FREE 8GB USB
96-Strip-Wells  /  $355 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,435 +1 FREE 8GB USB
10x96-Strip-Wells  /  $2,805 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BMP-6, ELISA Kit

★Popular Item★
 Also Known As   

Mouse BMP-6 (Bone Morphogenetic Protein 6) ELISA Kit

 Product Gene Name   

BMP-6 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2513110 COA    COA PDF
 OMIM    112266
 3D Structure    ModBase 3D Structure for P22004
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 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Mouse BMP-6. No significant cross-reactivity or interference between Mouse BMP-6 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Mouse BMP-6 and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    78.125-5000pg/mL
 Sensitivity    Min: 46.875pg/mL; Max: 5000pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of BMP-6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for BMP-6 purchase    MBS2513110 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the BMP-6, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 78.125-5000pg/mL in biological research samples containing BMP-6, with an estimated sensitivity of Min: 46.875pg/mL; Max: 5000pg/mL. The ELISA analytical biochemical technique of the MBS2513110 kit is based on BMP-6 antibody-BMP-6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BMP-6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BMP-6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for BMP-6 elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of BMP-6 in Mouse serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse BMP-6. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Mouse BMP-6 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse BMP-6, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Mouse BMP-6. You can calculate the concentration of Mouse BMP-6 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of BMP-6 elisa kit    BMP-6 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2513110. Click to request current manual
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NCBI/Uniprot data below describe general gene information for BMP-6. It may not necessarily be applicable to this product.
 NCBI GI #    4502425
 NCBI GeneID    654
 NCBI Accession #    NP_001709.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001718.4 [Other Products]
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 UniProt Primary Accession #    P22004 [Other Products]
 UniProt Secondary Accession #    Q5TCP3 [Other Products]
 UniProt Related Accession #    P22004 [Other Products]
 Molecular Weight    57,226 Da
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 NCBI Official Full Name    bone morphogenetic protein 6 preproprotein
 NCBI Official Synonym Full Names    bone morphogenetic protein 6
 NCBI Official Symbol    BMP6 [Similar Products]
 NCBI Official Synonym Symbols   
VGR; VGR1
[Similar Products]
 NCBI Protein Information    bone morphogenetic protein 6; BMP-6; VG-1-R; VG-1-related protein; VGR-1; Vg1-related sequence; vegetal related growth factor (TGFB-related); vegetal-related (TGFB related) cytokine
 UniProt Protein Name    Bone morphogenetic protein 6
 UniProt Synonym Protein Names   
VG-1-related protein; VG-1-R; VGR-1
 UniProt Gene Name    BMP6 [Similar Products]
 UniProt Synonym Gene Names    VGR; BMP-6; VG-1-R; VGR-1 [Similar Products]
 UniProt Entry Name    BMP6_HUMAN
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 NCBI Summary for BMP-6    The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity. [provided by RefSeq, Jul 2008]
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 UniProt Comments for BMP-6    BMP6: Induces cartilage and bone formation. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 6p24-p23

Cellular Component: extracellular space; cytoplasm

Molecular Function: growth factor activity; protein heterodimerization activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: cellular iron ion homeostasis; response to glucocorticoid stimulus; BMP signaling pathway; regulation of apoptosis; response to magnesium ion; positive regulation of endothelial cell differentiation; positive regulation of aldosterone biosynthetic process; male genitalia development; kidney development; inflammatory response; skeletal development; response to iron ion; endochondral ossification; response to retinoic acid; positive regulation of bone mineralization; osteoblast differentiation; positive regulation of osteoblast differentiation; positive regulation of chondrocyte differentiation; positive regulation of protein secretion; eye development; regulation of MAPKKK cascade; cartilage development; positive regulation of endothelial cell proliferation; immune response; positive regulation of transcription from RNA polymerase II promoter; response to activity; positive regulation of neuron differentiation; positive regulation of epithelial cell proliferation; growth
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 Research Articles on BMP-6    1. BMP-6 secreted by prostate cancer cells induces IL-6 expression in macrophages; IL-6, in turn, stimulates the neuroendocrine differentiation of prostate cancer cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with BMP-6 elisa kitPathways associated with BMP-6 elisa kit
 Reference Product  PubMed Publications
 BMPR2 elisa kit  >59 publications with BMP-6 and BMPR2
 BMPR1A elisa kit  >33 publications with BMP-6 and BMPR1A
 SMAD5 elisa kit  >27 publications with BMP-6 and SMAD5
 BMPR1B elisa kit  >16 publications with BMP-6 and BMPR1B
 ACVR2A elisa kit  >4 publications with BMP-6 and ACVR2A
 NOG elisa kit  >2 publications with BMP-6 and NOG
 Products by Pathway  Pathway Diagram
 BMP Receptor Signaling Pathway antibodies  BMP Receptor Signaling Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Id Signaling Pathway antibodies  Id Signaling Pathway Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
Diseases associated with BMP-6 elisa kitOrgans/Tissues associated with BMP-6 elisa kit
 Disease Name  Pubmed Publications
 Anemia Antibodies  >33 publications with BMP-6 and Anemia
 Inflammation Antibodies  >33 publications with BMP-6 and Inflammation
 Disease Models, Animal Antibodies  >28 publications with BMP-6 and Disease Models, Animal
 Hemochromatosis Antibodies  >26 publications with BMP-6 and Hemochromatosis
 Liver Diseases Antibodies  >18 publications with BMP-6 and Liver Diseases
 Adenocarcinoma Antibodies  >17 publications with BMP-6 and Adenocarcinoma
 Fibrosis Antibodies  >13 publications with BMP-6 and Fibrosis
 Kidney Diseases Antibodies  >12 publications with BMP-6 and Kidney Diseases
 Necrosis Antibodies  >12 publications with BMP-6 and Necrosis
 Nervous System Diseases Antibodies  >11 publications with BMP-6 and Nervous System Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >89 publications with BMP-6 and Blood
 Connective Tissue Antibodies  >45 publications with BMP-6 and Connective Tissue
 Ovary Antibodies  >37 publications with BMP-6 and Ovary
 Embryonic Tissue Antibodies  >32 publications with BMP-6 and Embryonic Tissue
 Brain Antibodies  >31 publications with BMP-6 and Brain
 Vascular Antibodies  >26 publications with BMP-6 and Vascular
 Prostate Antibodies  >25 publications with BMP-6 and Prostate
 Kidney Antibodies  >19 publications with BMP-6 and Kidney
 Mouth Antibodies  >13 publications with BMP-6 and Mouth
 Lung Antibodies  >12 publications with BMP-6 and Lung
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