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BMP1 elisa kit :: Mouse Bone Morphogenetic Protein 1 (BMP1) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2019285 (SPECIAL PROMOTION: Get FREE Starbucks gift card ($5 for 48-Wells-Kit or $10 for 96-Wells-Kit. Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Typical Standard Curve/Testing Data
Unit / Price
24-Strip-Wells  /  $260 +1 FREE 8GB USB
48-Strip-Wells  /  $465 +1 FREE 8GB USB
96-Strip-Wells  /  $625 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,530 +3 FREE 8GB USB
10x96-Strip-Wells  /  $4,565 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Bone Morphogenetic Protein 1 (BMP1), ELISA Kit

★Popular Item★
 Also Known As   

Bone Morphogenetic Protein 1 (BMP1) ELISA Kit

 Product Synonym Names    PCOLC; PCP; TLD; mTld; Procollagen C Proteinase; Mammalian tolloid protein
 Product Gene Name   

BMP1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P98063
 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Bone Morphogenetic Protein 1 (BMP1).
No significant cross-reactivity or interference between Bone Morphogenetic Protein 1 (BMP1) and analogues was observed.
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 Assay Type    Double-antibody Sandwich
 Samples    Serum, Plasma, Tissue homogenates, Cell lysates and Other Biological Fluids
 Detection Range    78-5,000pg/mL
 Sensitivity    < 30pg/mL
 Application    Enzyme-linked immunosorbent assay for Antigen Detection.
 Intra-assay Precision (Precision within an assay)    3 samples with low, middle and high level Bone Morphogenetic Protein 1 (BMP1) were tested 20 times on one plate, respectively.
 Inter-assay Precision (Precision between assays)    3 samples with low, middle and high level Bone Morphogenetic Protein 1 (BMP1) were tested on 3 different plates, 8 replicates in each plate.
 CV(%) =    SD/meanX100
 Intra-Assay    CV<10%
 Inter-Assay    CV<12%
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 Preparation and Storage    The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of BMP1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for BMP1 purchase    MBS2019285 is a ready-to-use microwell, strip plate Double-antibody Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Bone Morphogenetic Protein 1 (BMP1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 78-5,000pg/mL in biological research samples containing BMP1, with an estimated sensitivity of < 30pg/mL. The ELISA analytical biochemical technique of the MBS2019285 kit is based on BMP1 antibody-BMP1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BMP1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BMP1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Tissue homogenates, Cell lysates and Other Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for BMP1 elisa kit

   The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Bone Morphogenetic Protein 1 (BMP1). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Bone Morphogenetic Protein 1 (BMP1). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Bone Morphogenetic Protein 1 (BMP1), biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Bone Morphogenetic Protein 1 (BMP1) in the samples is then determined by comparing the O.D. of the samples to the standard curve.
 Product Categories/Family for BMP1 elisa kit    Developmental science
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 Typical Standard Curve/Testing Data of BMP1 elisa kit    BMP1 elisa kit Typical Standard Curve/Testing Data image
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Sample Manual Insert of MBS2019285. Click to request current manual
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NCBI/Uniprot data below describe general gene information for BMP1. It may not necessarily be applicable to this product.
 NCBI GI #    42734447
 NCBI GeneID    12153
 NCBI Accession #    NP_033885.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_009755.3 [Other Products]
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 UniProt Primary Accession #    P98063 [Other Products]
 UniProt Secondary Accession #    Q6NZM2 [Other Products]
 UniProt Related Accession #    P98063 [Other Products]
 Molecular Weight    111,666 Da
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 NCBI Official Full Name    bone morphogenetic protein 1
 NCBI Official Synonym Full Names    bone morphogenetic protein 1
 NCBI Official Symbol    Bmp1 [Similar Products]
 NCBI Official Synonym Symbols   
Pcp; Tld
[Similar Products]
 NCBI Protein Information    bone morphogenetic protein 1
 UniProt Protein Name    Bone morphogenetic protein 1
 UniProt Synonym Protein Names   
Mammalian tolloid protein; mTld; Procollagen C-proteinase; PCP
 Protein Family    Bone morphogenetic protein
 UniProt Gene Name    Bmp1 [Similar Products]
 UniProt Synonym Gene Names    BMP-1; mTld; PCP [Similar Products]
 UniProt Entry Name    BMP1_MOUSE
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 NCBI Summary for BMP1    This gene encodes a metalloproteinase that plays an essential role in the formation of the extracellular matrix and is also able to induce ectopic bone formation. Unlike other bone morphogenetic proteins, the protein encoded by this gene is not closely related to transforming growth factor-beta. This protein plays in role several developmental processes. In humans, mutations in this gene are associated with osteogenesis imperfecta and with increased bone mineral density and multiple recurrent fractures. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
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 UniProt Comments for BMP1    BMP1: Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD). Defects in BMP1 are a cause of autosomal recessive osteogenesis imperfecta (AR-OI). A connective tissue disorder characterized by bone fragility, progressively deforming bones, bowing of limbs due to multiple fractures, very short stature, a triangular face, severe scoliosis, and grayish sclera. AR-OI due to BMP1 mutations belongs to the group of osteogenesis imperfecta type III in the Sillence classification. Belongs to the peptidase M12A family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease; Cytokine; EC 3.4.24.19

Cellular Component: Golgi apparatus; extracellular space; proteinaceous extracellular matrix; extracellular region

Molecular Function: peptidase activity; protein binding; growth factor activity; zinc ion binding; hydrolase activity; metallopeptidase activity; metalloendopeptidase activity; metal ion binding; cytokine activity; calcium ion binding

Biological Process: ossification; cartilage development; multicellular organismal development; proteolysis; cell differentiation
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 Research Articles on BMP1    1. The presented data demonstrate Bmp1/Tll1 products to be of profound importance to bone growth and modeling.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with BMP1 elisa kitDiseases associated with BMP1 elisa kit
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Anchoring Fibril Formation Pathway antibodies  Anchoring Fibril Formation Pathway Diagram
 Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies  Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
 Collagen Biosynthesis And Modifying Enzymes Pathway antibodies  Collagen Biosynthesis And Modifying Enzymes Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 Crosslinking Of Collagen Fibrils Pathway antibodies  Crosslinking Of Collagen Fibrils Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 HDL-mediated Lipid Transport Pathway antibodies  HDL-mediated Lipid Transport Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >23 publications with BMP1 and Fibrosis
 Disease Models, Animal Antibodies  >12 publications with BMP1 and Disease Models, Animal
 Nervous System Diseases Antibodies  >7 publications with BMP1 and Nervous System Diseases
 Neoplasm Metastasis Antibodies  >6 publications with BMP1 and Neoplasm Metastasis
 Kidney Diseases Antibodies  >5 publications with BMP1 and Kidney Diseases
 Breast Neoplasms Antibodies  >4 publications with BMP1 and Breast Neoplasms
 Inflammation Antibodies  >4 publications with BMP1 and Inflammation
 Lung Neoplasms Antibodies  >4 publications with BMP1 and Lung Neoplasms
 Myocardial Infarction Antibodies  >4 publications with BMP1 and Myocardial Infarction
 Neoplasms, Experimental Antibodies  >3 publications with BMP1 and Neoplasms, Experimental
Organs/Tissues associated with BMP1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >243 publications with BMP1 and Bone
 Embryonic Tissue Antibodies  >27 publications with BMP1 and Embryonic Tissue
 Muscle Antibodies  >21 publications with BMP1 and Muscle
 Blood Antibodies  >18 publications with BMP1 and Blood
 Kidney Antibodies  >17 publications with BMP1 and Kidney
 Bone Marrow Antibodies  >16 publications with BMP1 and Bone Marrow
 Skin Antibodies  >15 publications with BMP1 and Skin
 Heart Antibodies  >15 publications with BMP1 and Heart
 Eye Antibodies  >13 publications with BMP1 and Eye
 Brain Antibodies  >12 publications with BMP1 and Brain
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