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BMP-6 elisa kit :: Mouse Bone Morphogenetic Protein 6 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS763317
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $300 +1 FREE 8GB USB
96-Strip-Wells  /  $415 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,425 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Bone Morphogenetic Protein 6 (BMP-6), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Bone Morphogenetic Protein 6 ELISA Kit

 Product Synonym Names    BMP-6 (Bone Morphogenetic Protein 6)/BMP6/VGR/VGR1
 Product Gene Name   

BMP-6 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS763317 QC Report    QC Report PDF
 OMIM    112266
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 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of BMP-6 . No significant cross-reactivity or interference between BMP-6 and analogues was observed.
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 Samples    Serum, plasma and other biological fluids.
 Assay Type    Sandwich ELISA, Double Antibody
 Detection Range    78.125-5000pg/ml
 Sensitivity    46.875pg/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level BMP-6 were tested 20 times on one plate, respectively. Intra-Assay: CV<8%
 Inter-assay Precision    Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level BMP-6 were tested on 3 different plates, 8 replicates in each plate. CV (%) = SD/meanX100. Inter-Assay: CV<10%
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 Preparation and Storage    Store at 4 degree C if kit is to be used within 1 week. Stable for 6 months (if micro ELISA Plate, Lyophilized Standard and Concentrated Biotinylated Detection Protein stored at-20 degree C. Other components at 2-8 degree C). Stable for 12 months (if the entire kit is stored at-20 degree C).
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of BMP-6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for BMP-6 purchase    MBS763317 is a ready-to-use microwell, strip plate Sandwich, Double Antibody ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Bone Morphogenetic Protein 6 (BMP-6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 78.125-5000pg/ml in biological research samples containing BMP-6, with an estimated sensitivity of 46.875pg/ml. The ELISA analytical biochemical technique of the MBS763317 kit is based on BMP-6 antibody-BMP-6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BMP-6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BMP-6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Typical Testing Data/Standard Curve (for reference only) of BMP-6 elisa kit    BMP-6 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS763317. Click to request current manual
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NCBI/Uniprot data below describe general gene information for BMP-6. It may not necessarily be applicable to this product.
 NCBI GI #    3492993
 NCBI GeneID    654
 NCBI Accession #    AAC33283.1 [Other Products]
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 UniProt Secondary Accession #    Q5TCP3 [Other Products]
 UniProt Related Accession #    P22004 [Other Products]
 Molecular Weight    57,226 Da
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 NCBI Official Full Name    bone morphogenetic protein 6, partial
 NCBI Official Synonym Full Names    bone morphogenetic protein 6
 NCBI Official Symbol    BMP6 [Similar Products]
 NCBI Official Synonym Symbols   
VGR; VGR1
[Similar Products]
 NCBI Protein Information    bone morphogenetic protein 6
 UniProt Protein Name    Bone morphogenetic protein 6
 UniProt Synonym Protein Names   
VG-1-related protein; VG-1-R; VGR-1
 Protein Family    Bone morphogenetic protein
 UniProt Gene Name    BMP6 [Similar Products]
 UniProt Synonym Gene Names    VGR; BMP-6; VG-1-R; VGR-1 [Similar Products]
 UniProt Entry Name    BMP6_HUMAN
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 NCBI Summary for BMP-6    The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity. [provided by RefSeq, Jul 2008]
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 UniProt Comments for BMP-6    BMP6: Induces cartilage and bone formation. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 6p24-p23

Cellular Component: cytoplasm; extracellular space

Molecular Function: cytokine activity; growth factor activity; protein heterodimerization activity; transforming growth factor beta receptor binding

Biological Process: BMP signaling pathway; cartilage development; cellular iron ion homeostasis; endochondral ossification; eye development; growth; immune response; inflammatory response; kidney development; male genitalia development; negative regulation of transcription from RNA polymerase II promoter; osteoblast differentiation; positive regulation of aldosterone biosynthetic process; positive regulation of bone mineralization; positive regulation of chondrocyte differentiation; positive regulation of endothelial cell differentiation; positive regulation of endothelial cell proliferation; positive regulation of epithelial cell proliferation; positive regulation of lipopolysaccharide-mediated signaling pathway; positive regulation of neuron differentiation; positive regulation of osteoblast differentiation; positive regulation of protein secretion; positive regulation of transcription from RNA polymerase II promoter; regulation of apoptosis; regulation of MAPKKK cascade; response to activity; response to glucocorticoid stimulus; response to magnesium ion; response to retinoic acid; skeletal development
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 Research Articles on BMP-6    1. These observations imply that crosstalk between the VEGF and BMP-6 signaling pathways enhances osteogenic differentiation of MSCs.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with BMP-6 elisa kitPathways associated with BMP-6 elisa kit
 Reference Product  PubMed Publications
 BMPR2 elisa kit  >61 publications with BMP-6 and BMPR2
 SMAD1 elisa kit  >60 publications with BMP-6 and SMAD1
 SMAD5 elisa kit  >30 publications with BMP-6 and SMAD5
 BMPR1A elisa kit  >18 publications with BMP-6 and BMPR1A
 BMPR1B elisa kit  >17 publications with BMP-6 and BMPR1B
 SMAD7 elisa kit  >11 publications with BMP-6 and SMAD7
 ACVR2A elisa kit  >5 publications with BMP-6 and ACVR2A
 NOG elisa kit  >3 publications with BMP-6 and NOG
 Products by Pathway  Pathway Diagram
 BMP Receptor Signaling Pathway antibodies  BMP Receptor Signaling Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 BMP Signaling Pathway antibodies  BMP Signaling Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Id Signaling Pathway antibodies  Id Signaling Pathway Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
Diseases associated with BMP-6 elisa kitOrgans/Tissues associated with BMP-6 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >40 publications with BMP-6 and Inflammation
 Anemia Antibodies  >38 publications with BMP-6 and Anemia
 Hemochromatosis Antibodies  >31 publications with BMP-6 and Hemochromatosis
 Disease Models, Animal Antibodies  >31 publications with BMP-6 and Disease Models, Animal
 Liver Diseases Antibodies  >22 publications with BMP-6 and Liver Diseases
 Fibrosis Antibodies  >15 publications with BMP-6 and Fibrosis
 Kidney Diseases Antibodies  >13 publications with BMP-6 and Kidney Diseases
 Necrosis Antibodies  >13 publications with BMP-6 and Necrosis
 Nervous System Diseases Antibodies  >13 publications with BMP-6 and Nervous System Diseases
 Osteoarthritis Antibodies  >9 publications with BMP-6 and Osteoarthritis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >97 publications with BMP-6 and Blood
 Connective Tissue Antibodies  >48 publications with BMP-6 and Connective Tissue
 Ovary Antibodies  >42 publications with BMP-6 and Ovary
 Embryonic Tissue Antibodies  >34 publications with BMP-6 and Embryonic Tissue
 Brain Antibodies  >32 publications with BMP-6 and Brain
 Vascular Antibodies  >31 publications with BMP-6 and Vascular
 Prostate Antibodies  >26 publications with BMP-6 and Prostate
 Kidney Antibodies  >23 publications with BMP-6 and Kidney
 Mouth Antibodies  >19 publications with BMP-6 and Mouth
 Lung Antibodies  >13 publications with BMP-6 and Lung
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