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C1qR1 elisa kit :: Mouse C1qR1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2503111
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C1qR1, ELISA Kit

★Popular Item★
 Also Known As   

Mouse C1qR1 (Complement Component 1Q Receptor1) ELISA Kit

 Product Gene Name   

C1qR1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    120577
 3D Structure    ModBase 3D Structure for Q9NPY3
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 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Mouse C1qR1. No significant cross-reactivity or interference between Mouse C1qR1 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Mouse C1qR1 and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.781-50ng/mL
 Sensitivity    Min: 0.469ng/mL; Max: 50ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of C1qR1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for C1qR1 purchase    MBS2503111 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the C1qR1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.781-50ng/mL in biological research samples containing C1qR1, with an estimated sensitivity of Min: 0.469ng/mL; Max: 50ng/mL. The ELISA analytical biochemical technique of the MBS2503111 kit is based on C1qR1 antibody-C1qR1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect C1qR1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, C1qR1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for C1qR1 elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of C1qR1 in Mouse serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse C1qR1. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Mouse C1qR1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse C1qR1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Mouse C1qR1. You can calculate the concentration of Mouse C1qR1 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of C1qR1 elisa kit    C1qR1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2503111. Click to request current manual
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NCBI/Uniprot data below describe general gene information for C1qR1. It may not necessarily be applicable to this product.
 NCBI GI #    88758613
 NCBI GeneID    22918
 NCBI Accession #    NP_036204.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_012072.3 [Other Products]
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 UniProt Primary Accession #    Q9NPY3 [Other Products]
 UniProt Secondary Accession #    O00274 [Other Products]
 UniProt Related Accession #    Q9NPY3 [Other Products]
 Molecular Weight    68,560 Da
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 NCBI Official Full Name    complement component C1q receptor
 NCBI Official Synonym Full Names    CD93 molecule
 NCBI Official Symbol    CD93 [Similar Products]
 NCBI Official Synonym Symbols   
C1QR1; C1qRP; CDw93; ECSM3; MXRA4; C1qR(P); dJ737E23.1
[Similar Products]
 NCBI Protein Information    complement component C1q receptor; C1q receptor 1; C1q/MBL/SPA receptor; C1qR; CD93 antigen; complement component 1 q subcomponent receptor 1; complement component 1, q subcomponent, receptor 1; matrix-remodeling-associated protein 4; matrix-remodelling associated 4
 UniProt Protein Name    Complement component C1q receptor
 UniProt Synonym Protein Names   
C1q/MBL/SPA receptor; C1qR; C1qR(p); C1qRp; CDw93; Complement component 1 q subcomponent receptor 1; Matrix-remodeling-associated protein 4; CD_antigen: CD93
 UniProt Gene Name    CD93 [Similar Products]
 UniProt Synonym Gene Names    C1QR1; MXRA4; C1qR; C1qR(p); C1qRp [Similar Products]
 UniProt Entry Name    C1QR1_HUMAN
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 NCBI Summary for C1qR1    The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. [provided by RefSeq, Jul 2008]
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 UniProt Comments for C1qR1    CD93: Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 20p11.21

Cellular Component: cell surface; cytoplasmic membrane-bound vesicle; integral to membrane; plasma membrane

Molecular Function: protein binding; complement component C1q binding; calcium ion binding; receptor activity; carbohydrate binding

Biological Process: macrophage activation; cell-cell adhesion; viral reproduction; phagocytosis
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 Research Articles on C1qR1    1. The data indicate that gC1qR inhibits viability, migration and proliferation of cervical squamous cells carcinoma via the p38 MAPK signalling pathway.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with C1qR1 elisa kitOrgans/Tissues associated with C1qR1 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >20 publications with C1qR1 and Inflammation
 Autoimmune Diseases Antibodies  >6 publications with C1qR1 and Autoimmune Diseases
 Brain Diseases Antibodies  >4 publications with C1qR1 and Brain Diseases
 Nervous System Diseases Antibodies  >4 publications with C1qR1 and Nervous System Diseases
 Necrosis Antibodies  >3 publications with C1qR1 and Necrosis
 Asthma Antibodies  >2 publications with C1qR1 and Asthma
 Lung Diseases Antibodies  >2 publications with C1qR1 and Lung Diseases
 Edema Antibodies  >2 publications with C1qR1 and Edema
 Brain Edema Antibodies  >2 publications with C1qR1 and Brain Edema
 Proteinuria Antibodies  >1 publications with C1qR1 and Proteinuria
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with C1qR1 and Bone
 Bone Marrow Antibodies  >12 publications with C1qR1 and Bone Marrow
 Vascular Antibodies  >10 publications with C1qR1 and Vascular
 Brain Antibodies  >6 publications with C1qR1 and Brain
 Spleen Antibodies  >6 publications with C1qR1 and Spleen
 Umbilical Cord Antibodies  >3 publications with C1qR1 and Umbilical Cord
 Liver Antibodies  >3 publications with C1qR1 and Liver
 Lymph Node Antibodies  >3 publications with C1qR1 and Lymph Node
 Muscle Antibodies  >2 publications with C1qR1 and Muscle
 Embryonic Tissue Antibodies  >2 publications with C1qR1 and Embryonic Tissue
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