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CACYBP elisa kit :: Mouse CACYBP ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2508565
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CACYBP, ELISA Kit

★Popular Item★
 Also Known As   

Mouse CACYBP (Calcyclin Binding Protein) ELISA Kit

 Product Gene Name   

CACYBP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    606186
 3D Structure    ModBase 3D Structure for Q9HB71
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 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Mouse CACYBP. No significant cross-reactivity or interference between Mouse CACYBP and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Mouse CACYBP and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    15.625-1000pg/mL
 Sensitivity    Min: 9.375pg/mL; Max: 1000pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CACYBP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CACYBP purchase    MBS2508565 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CACYBP, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.625-1000pg/mL in biological research samples containing CACYBP, with an estimated sensitivity of Min: 9.375pg/mL; Max: 1000pg/mL. The ELISA analytical biochemical technique of the MBS2508565 kit is based on CACYBP antibody-CACYBP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CACYBP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CACYBP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CACYBP elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of CACYBP in Mouse serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse CACYBP. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Mouse CACYBP and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse CACYBP, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Mouse CACYBP. You can calculate the concentration of Mouse CACYBP in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of CACYBP elisa kit    CACYBP elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2508565. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CACYBP. It may not necessarily be applicable to this product.
 NCBI GI #    60218913
 NCBI GeneID    27101
 NCBI Accession #    NP_001007215.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001007214.1 [Other Products]
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 UniProt Primary Accession #    Q9HB71 [Other Products]
 UniProt Secondary Accession #    O60666; Q5R370; Q5R371; B2ZWH2; B3KSF1 [Other Products]
 UniProt Related Accession #    Q9HB71 [Other Products]
 Molecular Weight    21,228 Da
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 NCBI Official Full Name    calcyclin-binding protein isoform 2
 NCBI Official Synonym Full Names    calcyclin binding protein
 NCBI Official Symbol    CACYBP [Similar Products]
 NCBI Official Synonym Symbols   
SIP; GIG5; PNAS-107; S100A6BP
[Similar Products]
 NCBI Protein Information    calcyclin-binding protein; S100A6-binding protein; Siah-interacting protein (SIP); growth-inhibiting gene 5 protein; hCacyBP
 UniProt Protein Name    Calcyclin-binding protein
 UniProt Synonym Protein Names   
S100A6-binding protein; Siah-interacting protein
 Protein Family    Calcyclin-binding protein
 UniProt Gene Name    CACYBP [Similar Products]
 UniProt Synonym Gene Names    S100A6BP; SIP; CacyBP; hCacyBP [Similar Products]
 UniProt Entry Name    CYBP_HUMAN
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 NCBI Summary for CACYBP    The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CACYBP    CACYBP: a nuclear/cytoplasmic protein involved in calcium-dependent ubiquitination and proteosomal degradation of target proteins. A possible molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1). Interacts with proteins of the S100 family at physiological calcium concentrations. Component of some large E3 complexes and interacts directly with SIAH1, SIAH2 and SKP1A. Cytoplasmic at low calcium concentrations. In neuroblastoma cells, after a retinoic acid (RA) induction and calcium increase, it localizes in both the nucleus and cytoplasm. The nuclear fraction may be phosphorylated. Two alternatively spliced isoforms have been described.

Protein type: Ubiquitin conjugating system; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 1q24-q25

Cellular Component: nucleoplasm; neuron projection; nuclear envelope lumen; cytoplasm; beta-catenin destruction complex

Molecular Function: protein binding; protein homodimerization activity

Biological Process: cardiac muscle cell differentiation; positive regulation of DNA replication; aging
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 Research Articles on CACYBP    1. Overexpression of CacyBP is associated with glioma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CACYBP elisa kitPathways associated with CACYBP elisa kit
 Reference Product  PubMed Publications
 S100A6 elisa kit  >21 publications with CACYBP and S100A6
 SIAH1 elisa kit  >4 publications with CACYBP and SIAH1
 APC elisa kit  >1 publications with CACYBP and APC
 GSK3B elisa kit  >1 publications with CACYBP and GSK3B
 Products by Pathway  Pathway Diagram
 Gastric Cancer Network 2 Pathway antibodies  Gastric Cancer Network 2 Pathway Diagram
 Wnt Signaling Pathway antibodies  Wnt Signaling Pathway Diagram
 Wnt Signaling Pathway antibodies  Wnt Signaling Pathway Diagram
Diseases associated with CACYBP elisa kitOrgans/Tissues associated with CACYBP elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >5 publications with CACYBP and Nervous System Diseases
 Neoplasms, Experimental Antibodies  >3 publications with CACYBP and Neoplasms, Experimental
 Kidney Diseases Antibodies  >3 publications with CACYBP and Kidney Diseases
 Breast Neoplasms Antibodies  >2 publications with CACYBP and Breast Neoplasms
 Disease Models, Animal Antibodies  >2 publications with CACYBP and Disease Models, Animal
 Cell Transformation, Neoplastic Antibodies  >1 publications with CACYBP and Cell Transformation, Neoplastic
 Cardiovascular Diseases Antibodies  >1 publications with CACYBP and Cardiovascular Diseases
 Heart Diseases Antibodies  >1 publications with CACYBP and Heart Diseases
 Acute Kidney Injury Antibodies  >1 publications with CACYBP and Acute Kidney Injury
 Liver Neoplasms Antibodies  >1 publications with CACYBP and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >17 publications with CACYBP and Brain
 Stomach Antibodies  >9 publications with CACYBP and Stomach
 Blood Antibodies  >5 publications with CACYBP and Blood
 Kidney Antibodies  >4 publications with CACYBP and Kidney
 Ascites Antibodies  >4 publications with CACYBP and Ascites
 Nerve Antibodies  >3 publications with CACYBP and Nerve
 Lymph Node Antibodies  >3 publications with CACYBP and Lymph Node
 Muscle Antibodies  >3 publications with CACYBP and Muscle
 Lymph Antibodies  >3 publications with CACYBP and Lymph
 Uterus Antibodies  >2 publications with CACYBP and Uterus
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