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CSE1L elisa kit :: Mouse CSE1 chromosome segregation 1-like (yeast) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9327495 CSE1L elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CSE1 chromosome segregation 1-like (yeast) (CSE1L), ELISA Kit

 Also Known As   

Mouse Exportin-2, CSE1L ELISA Kit

 Product Synonym Names    Mouse Exportin-2 (CSE1L) ELISA kit; CAS; CSE1; MGC117283; MGC130036; MGC130037; XPO2; CSE1 chromosome segregation 1-like protein; cellular apoptosis susceptibility protein; chromosome segregation 1-like; importin-alpha re-exporter; CSE1 chromosome segregation 1-like (yeast)
 Product Gene Name   

CSE1L elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q9ERK4
 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CSE1L elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CSE1L purchase    MBS9327495 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CSE1 chromosome segregation 1-like (yeast) (CSE1L) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CSE1L. The ELISA analytical biochemical technique of the MBS9327495 kit is based on CSE1L antibody-CSE1L antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CSE1L antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CSE1L. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for CSE1L. It may not necessarily be applicable to this product.
 NCBI GI #    12963737
 NCBI GeneID    110750
 NCBI Accession #    NP_076054.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_023565.3 [Other Products]
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 UniProt Primary Accession #    Q9ERK4 [Other Products]
 UniProt Related Accession #    Q9ERK4 [Other Products]
 Molecular Weight    110,455 Da
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 NCBI Official Full Name    exportin-2
 NCBI Official Synonym Full Names    chromosome segregation 1-like (S. cerevisiae)
 NCBI Official Symbol    Cse1l [Similar Products]
 NCBI Official Synonym Symbols   
Cas; Xpo2; Capts; AA407533; 2610100P18Rik
[Similar Products]
 NCBI Protein Information    exportin-2; exp2; importin-alpha re-exporter; chromosome segregation 1-like protein
 UniProt Protein Name    Exportin-2
 UniProt Synonym Protein Names   
Chromosome segregation 1-like protein; Importin-alpha re-exporter
 UniProt Gene Name    Cse1l [Similar Products]
 UniProt Synonym Gene Names    Xpo2; Exp2 [Similar Products]
 UniProt Entry Name    XPO2_MOUSE
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 UniProt Comments for CSE1L    Exportin-2: Export receptor for importin-alpha. Mediates importin- alpha re-export from the nucleus to the cytoplasm after import substrates (cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the importin-alpha from the export receptor. CSE1L/XPO2 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Belongs to the XPO2/CSE1 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear import; Nuclear export; Karyopherin

Cellular Component: nucleoplasm; membrane; cytoplasm; nucleus

Molecular Function: protein binding; Ran GTPase binding

Biological Process: intracellular protein transport; protein transport; transport
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 Research Articles on CSE1L    1. CSE1L knockdown reduced Ras-induced metastasis of B16F10 melanoma cells in C57BL/6 mice. v-H-Ras expression altered the cellular trafficking of CSE1L and increased CSE1L secretion.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with CSE1L elisa kitOrgans/Tissues associated with CSE1L elisa kit
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >13 publications with CSE1L and Carcinoma
 Adenocarcinoma Antibodies  >5 publications with CSE1L and Adenocarcinoma
 Neoplasm Metastasis Antibodies  >5 publications with CSE1L and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >5 publications with CSE1L and Breast Neoplasms
 Liver Diseases Antibodies  >4 publications with CSE1L and Liver Diseases
 Neoplasms, Experimental Antibodies  >4 publications with CSE1L and Neoplasms, Experimental
 Head and Neck Neoplasms Antibodies  >4 publications with CSE1L and Head and Neck Neoplasms
 Nervous System Diseases Antibodies  >3 publications with CSE1L and Nervous System Diseases
 Carcinoma, Hepatocellular Antibodies  >3 publications with CSE1L and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >3 publications with CSE1L and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >5 publications with CSE1L and Liver
 Blood Antibodies  >4 publications with CSE1L and Blood
 Brain Antibodies  >3 publications with CSE1L and Brain
 Skin Antibodies  >2 publications with CSE1L and Skin
 Kidney Antibodies  >2 publications with CSE1L and Kidney
 Lymph Node Antibodies  >2 publications with CSE1L and Lymph Node
 Lung Antibodies  >1 publications with CSE1L and Lung
 Pancreas Antibodies  >1 publications with CSE1L and Pancreas
 Embryonic Tissue Antibodies  >1 publications with CSE1L and Embryonic Tissue
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