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CXCL16 elisa kit :: Mouse CXCL16 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS175996
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
1x96 Wells  /  $455 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CXCL16, ELISA Kit

 Also Known As   

Mouse CXCL16 PicoKine ELISA Kit

 Product Synonym Names    C-X-C motif chemokine 16; chemokine (C-X-C motif) ligand 16; 0910001K24Rik; AV290116; BB024863; C X C motif chemokine 16; Chemokine (C X C motif) ligand 16; CXC chemokine ligand 16; CXCLG16; DN 491F10.6; Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SCYB16; Small inducible cytokine B; Small inducible cytokine B16; Small inducible cytokine B16 precursor; SR PSOX; SR PSOX/CXCL16 scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SRPSOX; Transmembrane chemokine CXCL16; Zinc finger, MYND-type containing 15; Zmynd15
 Product Gene Name   

CXCL16 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 3D Structure    ModBase 3D Structure for Q8BSU2
 Species Reactivity    Mouse
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 Specificity    Natural and recombinant mouse CXCL16
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 Samples    Cell culture supernates, serum and plasma (heparin, EDTA)
 Assay Type    Sandwich
 Detection Range    15.6pg/ml-1000pg/ml
 Sensitivity    < 1pg/ml
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 Preparation and Storage    Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of CXCL16 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CXCL16 purchase    MBS175996 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CXCL16, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.6pg/ml-1000pg/ml in biological research samples containing CXCL16, with an estimated sensitivity of < 1pg/ml. The ELISA analytical biochemical technique of the MBS175996 kit is based on CXCL16 antibody-CXCL16 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CXCL16 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CXCL16. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions such as Cell culture supernates, serum and plasma (heparin, EDTA). Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for CXCL16 elisa kit

   Principle of the assay: mouse CXCL16 ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from rat specific for CXCL16 has been precoated onto 96-well plates. Standards(E.coli,N27-P114) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for CXCL16 is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the mouse CXCL16 amount of sample captured in plate.
Background: Chemokine (C-X-C motif) ligand 16 (CXCL16) is a small cytokine belonging to the CXC chemokine family. Larger than other chemokines (with 254 amino acids), CXCL16 is composed of a CXC chemokine domain, a mucin-like stalk, a transmembrane domain and a cytoplasmic tail containing a potential tyrosine phosphorylation site that may bind SH2.1 These are unusual features for a chemokine, and allow CXCL16 to be expressed as a cell surfacebound molecule, as well as a soluble chemokine.2 CXCL16 is produced by dendritic cells found in the T cell zonesof lymphoid organs, and by cells found in the red pulp of the spleen.1 Cells that bind and migrate in response toCXCL16 include several subsets of T cells, and natural killer T (NKT) cells.1 CXCL16 interacts with the chemokinereceptor CXCR6, also known as Bonzo.1, 3 Expression of CXCL16 is induced by the inflammatory cytokinesIFN-gamma and TNF-alpha.2 The gene for human CXCL16 is located on chromosome 17p13.4 The standardproduct used in this kit is recombinant mouse CXCL16, consisting of 88 amino acids with the molecular mass of 9.9KDa.
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 Typical Testing Data/Standard Curve (for reference only) of CXCL16 elisa kit    CXCL16 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS175996
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NCBI/Uniprot data below describe general gene information for CXCL16. It may not necessarily be applicable to this product.
 NCBI GI #    37088434
 NCBI GeneID    66102
 NCBI Accession #    Q8BSU2.2 [Other Products]
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 UniProt Primary Accession #    Q8BSU2 [Other Products]
 UniProt Secondary Accession #    Q3UD70; Q5F2D5; Q8VE25; Q9EPB3 [Other Products]
 UniProt Related Accession #    Q8BSU2 [Other Products]
 Molecular Weight    26,896 Da
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 NCBI Official Full Name    C-X-C motif chemokine 16
 NCBI Official Synonym Full Names    chemokine (C-X-C motif) ligand 16
 NCBI Official Symbol    Cxcl16 [Similar Products]
 NCBI Official Synonym Symbols   
SR-PSOX; Zmynd15; AV290116; BB024863; CXCL16v1; CXCL16v2; b2b498Clo; 0910001K24Rik
[Similar Products]
 NCBI Protein Information    C-X-C motif chemokine 16; SR-PSOX/CXCL16; Mutant line 498; Cxc chemokine ligand 16; small-inducible cytokine B16; transmembrane chemokine CXCL16; zinc finger, MYND-type containing 15; scavenger receptor for phosphatidylserine and oxidized low density lipoprotein
 UniProt Protein Name    C-X-C motif chemokine 16
 UniProt Synonym Protein Names   
Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SR-PSOX; Small-inducible cytokine B16; Transmembrane chemokine CXCL16
 Protein Family    C-X-C motif chemokine
 UniProt Gene Name    Cxcl16 [Similar Products]
 UniProt Synonym Gene Names    Srpsox; SR-PSOX [Similar Products]
 UniProt Entry Name    CXL16_MOUSE
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 UniProt Comments for CXCL16    CXCL16: Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis. Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Membrane protein, integral

Cellular Component: extracellular space; membrane; integral to membrane

Molecular Function: low-density lipoprotein receptor activity; chemokine receptor binding; chemokine activity; cytokine activity; scavenger receptor activity

Biological Process: receptor-mediated endocytosis; response to cytokine stimulus; chemotaxis; lymphocyte chemotaxis; positive regulation of cell growth; positive regulation of cell migration
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 Research Articles on CXCL16    1. CCL2 and CXCL16 chemokines produced by tumor-conditioned Gr-1(+)CD11b(+) myeloid cells synergistically induce angiogenesis in vitro by stimulating the ERK1/2 signaling pathway.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to Mouse CXCL16 PicoKine ELISA Kit
 Catalog #  Product Name  Catalog #  Product Name
 MBS2047155  Cy3-Linked Polyclonal Antibody to Chemokine C-X-C-Motif Ligand 16 (CXCL16)  MBS2024670  Chemokine C-X-C-Motif Ligand 16 (CXCL16) ELISA Kit
 MBS8207817  CXCL16 siRNA (Rat)  MBS2502223  Guinea pig CXCL16 (Chemokine C-X-C-Motif Ligand 16) ELISA Kit
 MBS2047148  APC-Linked Polyclonal Antibody to Chemokine C-X-C-Motif Ligand 16 (CXCL16)  MBS2513337  Porcine CXCL16 (Chemokine C-X-C-Motif Ligand 16) ELISA Kit
 MBS2047152  APC/CY7-Linked Polyclonal Antibody to Chemokine C-X-C-Motif Ligand 16 (CXCL16)  MBS535836  CXCL16 antibody
 MBS537369  CXCL16 protein  MBS845392  CXCL16, mouse recombinant
Products associated with CXCL16 elisa kitPathways associated with CXCL16 elisa kit
 Reference Product  PubMed Publications
 Cxcr6 elisa kit  >145 publications with CXCL16 and Cxcr6
 Cxcl10 elisa kit  >47 publications with CXCL16 and Cxcl10
 Cxcl12 elisa kit  >32 publications with CXCL16 and Cxcl12
 Cxcl9 elisa kit  >28 publications with CXCL16 and Cxcl9
 Ccl5 elisa kit  >26 publications with CXCL16 and Ccl5
 Cxcr3 elisa kit  >25 publications with CXCL16 and Cxcr3
 Cxcl13 elisa kit  >17 publications with CXCL16 and Cxcl13
 Ccr5 elisa kit  >13 publications with CXCL16 and Ccr5
 Ccl9 elisa kit  >3 publications with CXCL16 and Ccl9
 Ccl6 elisa kit  >2 publications with CXCL16 and Ccl6
 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
Diseases associated with CXCL16 elisa kitOrgans/Tissues associated with CXCL16 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >103 publications with CXCL16 and Inflammation
 Necrosis Antibodies  >61 publications with CXCL16 and Necrosis
 Disease Models, Animal Antibodies  >33 publications with CXCL16 and Disease Models, Animal
 Kidney Diseases Antibodies  >33 publications with CXCL16 and Kidney Diseases
 Carcinoma Antibodies  >25 publications with CXCL16 and Carcinoma
 Nervous System Diseases Antibodies  >22 publications with CXCL16 and Nervous System Diseases
 Liver Diseases Antibodies  >19 publications with CXCL16 and Liver Diseases
 Neoplasm Metastasis Antibodies  >18 publications with CXCL16 and Neoplasm Metastasis
 Fibrosis Antibodies  >17 publications with CXCL16 and Fibrosis
 Liver Neoplasms Antibodies  >9 publications with CXCL16 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >33 publications with CXCL16 and Kidney
 Lung Antibodies  >29 publications with CXCL16 and Lung
 Bone Marrow Antibodies  >21 publications with CXCL16 and Bone Marrow
 Brain Antibodies  >20 publications with CXCL16 and Brain
 Skin Antibodies  >15 publications with CXCL16 and Skin
 Spleen Antibodies  >14 publications with CXCL16 and Spleen
 Prostate Antibodies  >14 publications with CXCL16 and Prostate
 Joint Antibodies  >11 publications with CXCL16 and Joint
 Intestine Antibodies  >8 publications with CXCL16 and Intestine
 Connective Tissue Antibodies  >7 publications with CXCL16 and Connective Tissue
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