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CPE elisa kit :: Mouse Carboxypeptidase E ELISA Kit

Scan QR to view Datasheet Catalog #    MBS281703 CPE elisa kit
Unit / Price
48-Strip-Wells  /  $425 +1 FREE 8GB USB
96-Strip-Wells  /  $720 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,160 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,055 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Carboxypeptidase E (CPE), ELISA Kit

 Also Known As   

Mouse Carboxypeptidase E (CPE) ELISA Kit

 Product Gene Name   

CPE elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    114855
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 Species Reactivity    Mouse
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 Preparation and Storage    Store at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CPE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CPE purchase    MBS281703 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Carboxypeptidase E (CPE) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CPE. The ELISA analytical biochemical technique of the MBS281703 kit is based on CPE antibody-CPE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CPE antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CPE. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for CPE. It may not necessarily be applicable to this product.
 NCBI GI #    4503009
 NCBI GeneID    1363
 NCBI Accession #    NP_001864.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001873.2 [Other Products]
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 UniProt Secondary Accession #    Q9UIU9; A8K4N1; B3KR42; B4DFN4; D3DP33 [Other Products]
 UniProt Related Accession #    P16870 [Other Products]
 Molecular Weight    49,886 Da
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 NCBI Official Full Name    carboxypeptidase E preproprotein
 NCBI Official Synonym Full Names    carboxypeptidase E
 NCBI Official Symbol    CPE [Similar Products]
 NCBI Protein Information    carboxypeptidase E; CPH; carboxypeptidase H; enkephalin convertase; prohormone-processing carboxypeptidase; insulin granule-associated carboxypeptidase; cobalt-stimulated chromaffin granule carboxypeptidase
 UniProt Protein Name    Carboxypeptidase E
 UniProt Synonym Protein Names   
Carboxypeptidase H; CPH; Enkephalin convertase; Prohormone-processing carboxypeptidase
 Protein Family    Carboxypeptidase
 UniProt Gene Name    CPE [Similar Products]
 UniProt Synonym Gene Names    CPE; CPH [Similar Products]
 UniProt Entry Name    CBPE_HUMAN
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 NCBI Summary for CPE    This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CPE    CPE: Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing. Processes proinsulin. Belongs to the peptidase M14 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease; Secreted, signal peptide; Secreted; EC 3.4.17.10

Chromosomal Location of Human Ortholog: 4q32.3

Cellular Component: Golgi apparatus; secretory granule membrane; plasma membrane; nucleus

Molecular Function: carboxypeptidase activity; zinc ion binding; neurexin binding; cell adhesion molecule binding; metallocarboxypeptidase activity

Biological Process: insulin processing; cellular protein metabolic process; metabolic process; neuropeptide signaling pathway; protein modification process; proteolysis
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 Research Articles on CPE    1. Disruption of insulin receptor (IR) expression in beta cells has a direct impact on the expression of the convertase enzyme carboxypeptidase E (CPE) by inhibition of the eukaryotic translation initiation factor Eif4g1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CPE elisa kitPathways associated with CPE elisa kit
 Reference Product  PubMed Publications
 CCK elisa kit  >6 publications with CPE and CCK
 PCSK1N elisa kit  >6 publications with CPE and PCSK1N
 TRH elisa kit  >2 publications with CPE and TRH
 INS elisa kit  >2 publications with CPE and INS
 ARF6 elisa kit  >1 publications with CPE and ARF6
 Products by Pathway  Pathway Diagram
 Arf6 Trafficking Events Pathway antibodies  Arf6 Trafficking Events Pathway Diagram
 Insulin Processing Pathway antibodies  Insulin Processing Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Peptide Hormone Metabolism Pathway antibodies  Peptide Hormone Metabolism Pathway Diagram
 Type I Diabetes Mellitus Pathway antibodies  Type I Diabetes Mellitus Pathway Diagram
 Type I Diabetes Mellitus Pathway antibodies  Type I Diabetes Mellitus Pathway Diagram
Diseases associated with CPE elisa kitOrgans/Tissues associated with CPE elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >77 publications with CPE and Necrosis
 Disease Models, Animal Antibodies  >76 publications with CPE and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >74 publications with CPE and Cardiovascular Diseases
 Edema Antibodies  >62 publications with CPE and Edema
 Obesity Antibodies  >62 publications with CPE and Obesity
 Kidney Diseases Antibodies  >59 publications with CPE and Kidney Diseases
 Inflammation Antibodies  >58 publications with CPE and Inflammation
 Endocrine System Diseases Antibodies  >57 publications with CPE and Endocrine System Diseases
 Heart Diseases Antibodies  >55 publications with CPE and Heart Diseases
 Pulmonary Edema Antibodies  >49 publications with CPE and Pulmonary Edema
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >289 publications with CPE and Brain
 Kidney Antibodies  >267 publications with CPE and Kidney
 Lung Antibodies  >184 publications with CPE and Lung
 Heart Antibodies  >93 publications with CPE and Heart
 Skin Antibodies  >79 publications with CPE and Skin
 Liver Antibodies  >73 publications with CPE and Liver
 Eye Antibodies  >66 publications with CPE and Eye
 Pituitary Gland Antibodies  >54 publications with CPE and Pituitary Gland
 Muscle Antibodies  >54 publications with CPE and Muscle
 Mouth Antibodies  >53 publications with CPE and Mouth
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