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Add To Compare List COMP elisa kit :: Mouse Cartilage Oligomeric Matrix Protein (COMP) ELISA Kit Catalog # MBS451829 Unit / Price 48 Tests / $405 +1 FREE 8GB USB 96 Tests / $540 +1 FREE 8GB USB 5x96 Tests / $2,440 +3 FREE 8GB USB 10x96 Tests / $4,760 +5 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Cartilage Oligomeric Matrix Protein (COMP), ELISA Kit Popular Item Full Product Name Mouse Cartilage Oligomeric Matrix Protein (COMP) ELISA Kit Product Synonym Names MED; EDM1; EPD1; PSACH; THBS5; TSP-5; Pseudoachondroplasia,Epiphyseal Dysplasia 1,Multiple; Thrombospondin 5 Product Gene Name COMP elisa kit[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sample Manual Insert Download Sample PDF Manual View Sample PDF Manual 3D Structure ModBase 3D Structure for Q9R0G6 Species Reactivity Mouse Specificity This assay has high sensitivity and excellent specificity for detection of COMP. No significant cross-reactivity or interference between COMP and analogues was observed. Samples Serum, plasma or other biological fluids Assay Type Quantitative Sandwich Detection Range 3.12-200ng/mL Sensitivity < 1.45ng/mL Intra-assay Precision Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level COMP were tested 20 times on one plate, respectively. Intra-Assay: CV<10% Inter-assay Precision Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level COMP were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100. Inter-Assay: CV<12% Preparation and Storage For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C. ISO Certification Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory. Product Note Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details. Other Notes Small volumes of COMP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. Searchable Terms for COMP purchase MBS451829 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cartilage Oligomeric Matrix Protein (COMP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing COMP. The ELISA analytical biochemical technique of the MBS451829 kit is based on COMP antibody-COMP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect COMP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, COMP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%). TOP Related Product Information for COMP elisa kit Intended Uses: The kit is a sandwich enzyme immunoassay for the in vitro quantitative measurement of COMP in mouse serum, plasma or other biological fluids.Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to COMP. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to COMP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain COMP, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm +/- 10nm. The concentration of COMP in the samples is then determined by comparing the O.D. of the samples to the standard curve. Typical Testing Data/Standard Curve (for reference only) of COMP elisa kit TOP Sample Manual Insert of MBS451829. NCBI/Uniprot data below describe general gene information for COMP. It may not necessarily be applicable to this product. NCBI GI # 162287140 NCBI GeneID 12845 NCBI Accession # NP_057894.2 [Other Products] NCBI GenBank Nucleotide # NM_016685.2 [Other Products] UniProt Primary Accession # Q9R0G6 [Other Products] UniProt Secondary Accession # G3X8Q4[Other Products] UniProt Related Accession # Q9R0G6[Other Products] Molecular Weight 82,342 Da TOP NCBI Official Full Name cartilage oligomeric matrix protein NCBI Official Synonym Full Names cartilage oligomeric matrix protein NCBI Official Symbol Comp [Similar Products] NCBI Official Synonym Symbols TSP5 [Similar Products] NCBI Protein Information cartilage oligomeric matrix protein UniProt Protein Name Cartilage oligomeric matrix protein Protein Family Cartilage oligomeric matrix protein UniProt Gene Name Comp [Similar Products] UniProt Synonym Gene Names COMP [Similar Products] TOP TOP UniProt Comments for COMP May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP). Essential for maintaining a vascular smooth muscle cells (VSMCs) contractile/differentiated phenotype under physiological and pathological stimuli. Maintains this phenotype of VSMCs by interacting with ITGA7 (). Research Articles on COMP 1. COMP forms a complex with collagens intracellularly that is a prerequisite for collagen secretion. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with COMP elisa kit Reference Product PubMed Publications Matn1 elisa kit >68 publications with COMP and Matn1 Cd36 elisa kit >56 publications with COMP and Cd36 Matn3 elisa kit >32 publications with COMP and Matn3 Itga4 elisa kit >4 publications with COMP and Itga4 Itga2b elisa kit >2 publications with COMP and Itga2b Itga7 elisa kit >2 publications with COMP and Itga7 Matn4 elisa kit >2 publications with COMP and Matn4 Cd47 elisa kit >2 publications with COMP and Cd47 Pathways associated with COMP elisa kit Products by Pathway Pathway Diagram ECM Proteoglycans Pathway antibodies ECM Proteoglycans Pathway Diagram ECM-receptor Interaction Pathway antibodies ECM-receptor Interaction Pathway Diagram ECM-receptor Interaction Pathway antibodies ECM-receptor Interaction Pathway Diagram Extracellular Matrix Organization Pathway antibodies Extracellular Matrix Organization Pathway Diagram Focal Adhesion-PI3K-Akt-mTOR-signaling Pathway antibodies Focal Adhesion-PI3K-Akt-mTOR-signaling Pathway Diagram Focal Adhesion Pathway antibodies Focal Adhesion Pathway Diagram Focal Adhesion Pathway antibodies Focal Adhesion Pathway Diagram Integrin Cell Surface Interactions Pathway antibodies Integrin Cell Surface Interactions Pathway Diagram Malaria Pathway antibodies Malaria Pathway Diagram Malaria Pathway antibodies Malaria Pathway Diagram Diseases associated with COMP elisa kit Disease Name Pubmed Publications Disease Models, Animal Antibodies >2006 publications with COMP and Disease Models, Animal Inflammation Antibodies >1403 publications with COMP and Inflammation Necrosis Antibodies >1155 publications with COMP and Necrosis Immune System Diseases Antibodies >1087 publications with COMP and Immune System Diseases Nerve Degeneration Antibodies >977 publications with COMP and Nerve Degeneration Liver Diseases Antibodies >957 publications with COMP and Liver Diseases Kidney Diseases Antibodies >769 publications with COMP and Kidney Diseases Hypertension Antibodies >751 publications with COMP and Hypertension Fatty Liver Antibodies >668 publications with COMP and Fatty Liver Weight Loss Antibodies >613 publications with COMP and Weight Loss Organs/Tissues associated with COMP elisa kit Organ/Tissue Name Pubmed Publications Eye Antibodies >3992 publications with COMP and Eye Connective Tissue Antibodies >1949 publications with COMP and Connective Tissue Embryonic Tissue Antibodies >1912 publications with COMP and Embryonic Tissue Testis Antibodies >1872 publications with COMP and Testis Lung Antibodies >1667 publications with COMP and Lung Joint Antibodies >1251 publications with COMP and Joint Inner Ear Antibodies >719 publications with COMP and Inner Ear Thymus Antibodies >542 publications with COMP and Thymus Mammary Gland Antibodies >251 publications with COMP and Mammary Gland Fertilized Ovum Antibodies >92 publications with COMP and Fertilized Ovum TOP © 2006-24 MyBioSource.com. 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