View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List CASP1 elisa kit :: Mouse Caspase 1 (CASP1) ELISA Kit Catalog # MBS455768 Unit / Price 48 Tests / $460 +1 FREE 8GB USB 96 Tests / $605 +1 FREE 8GB USB 5x96 Tests / $2,740 +3 FREE 8GB USB 10x96 Tests / $5,350 +6 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Caspase 1 (CASP1), ELISA Kit Full Product Name Mouse Caspase 1 (CASP1) ELISA Kit Product Gene Name CASP1 elisa kit[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sample Manual Insert Download Sample PDF Manual View Sample PDF Manual 3D Structure ModBase 3D Structure for P29452 Species Reactivity Mouse Specificity This assay has high sensitivity and excellent specificity for detection of CASP1. No significant cross-reactivity or interference between CASP1 and analogues was observed. Samples Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. Assay Type Sandwich Detection Range 0.156-10ng/mL Sensitivity 0.059ng/mL Intra-assay Precision Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level CASP1 were tested 20 times on one plate, respectively. Intra-Assay: CV<10% Inter-assay Precision Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level CASP1 were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100. Inter-Assay: CV<12% Preparation and Storage For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C. ISO Certification Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory. Product Note Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details. Other Notes Small volumes of CASP1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. Searchable Terms for CASP1 purchase MBS455768 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Caspase 1 (CASP1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CASP1. The ELISA analytical biochemical technique of the MBS455768 kit is based on CASP1 antibody-CASP1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CASP1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CASP1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%). TOP Related Product Information for CASP1 elisa kit Intended Uses: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of CASP1 in mouse serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to CASP1. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to CASP1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain CASP1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm +/- 10nm. The concentration of CASP1 in the samples is then determined by comparing the O.D. of the samples to the standard curve. Typical Standard Curve/Testing Data of CASP1 elisa kit TOP Sample Manual Insert of MBS455768. NCBI/Uniprot data below describe general gene information for CASP1. It may not necessarily be applicable to this product. NCBI GI # 86198305 NCBI GeneID 12362 NCBI Accession # NP_033937.2 [Other Products] NCBI GenBank Nucleotide # NM_009807.2 [Other Products] UniProt Primary Accession # P29452 [Other Products] UniProt Related Accession # P29452[Other Products] Molecular Weight 45,640 Da TOP NCBI Official Full Name caspase-1 NCBI Official Synonym Full Names caspase 1 NCBI Official Symbol Casp1 [Similar Products] NCBI Official Synonym Symbols ICE; Il1bc [Similar Products] NCBI Protein Information caspase-1 UniProt Protein Name Caspase-1 UniProt Synonym Protein Names Interleukin-1 beta convertase; IL-1BC UniProt Gene Name Casp1 [Similar Products] UniProt Synonym Gene Names Il1bc; CASP-1; IL-1BC; ICE; IL-1 beta-converting enzyme [Similar Products] TOP TOP UniProt Comments for CASP1 Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Research Articles on CASP1 1. Demonstrate the utility of intracellular caspase 1 and extracellular CTSS proteolytic activities as surrogate biomarkers of lysosomal rupture and acute inflammation. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with CASP1 elisa kit Reference Product PubMed Publications Nlrp3 elisa kit >1453 publications with CASP1 and Nlrp3 Il18 elisa kit >660 publications with CASP1 and Il18 Pycard elisa kit >298 publications with CASP1 and Pycard Nlrc4 elisa kit >239 publications with CASP1 and Nlrc4 Il1b elisa kit >185 publications with CASP1 and Il1b Nod2 elisa kit >78 publications with CASP1 and Nod2 Mefv elisa kit >62 publications with CASP1 and Mefv Naip5 elisa kit >41 publications with CASP1 and Naip5 Nlrp1b elisa kit >22 publications with CASP1 and Nlrp1b Nfkb1 elisa kit >8 publications with CASP1 and Nfkb1 Pathways associated with CASP1 elisa kit Products by Pathway Pathway Diagram Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram Apoptosis Pathway antibodies Apoptosis Pathway Diagram Cytokine Signaling In Immune System Pathway antibodies Cytokine Signaling In Immune System Pathway Diagram Cytosolic DNA-sensing Pathway antibodies Cytosolic DNA-sensing Pathway Diagram Cytosolic DNA-sensing Pathway antibodies Cytosolic DNA-sensing Pathway Diagram IL-1 Signaling Pathway antibodies IL-1 Signaling Pathway Diagram Immune System Pathway antibodies Immune System Pathway Diagram Inflammasomes Pathway antibodies Inflammasomes Pathway Diagram Influenza A Pathway antibodies Influenza A Pathway Diagram Diseases associated with CASP1 elisa kit Disease Name Pubmed Publications Inflammation Antibodies >1891 publications with CASP1 and Inflammation Necrosis Antibodies >757 publications with CASP1 and Necrosis Disease Models, Animal Antibodies >473 publications with CASP1 and Disease Models, Animal Nervous System Diseases Antibodies >437 publications with CASP1 and Nervous System Diseases Liver Diseases Antibodies >171 publications with CASP1 and Liver Diseases Kidney Diseases Antibodies >128 publications with CASP1 and Kidney Diseases Heart Diseases Antibodies >119 publications with CASP1 and Heart Diseases Hypersensitivity Antibodies >118 publications with CASP1 and Hypersensitivity Fibrosis Antibodies >104 publications with CASP1 and Fibrosis Obesity Antibodies >88 publications with CASP1 and Obesity Organs/Tissues associated with CASP1 elisa kit Organ/Tissue Name Pubmed Publications Blood Antibodies >1313 publications with CASP1 and Blood Other Antibodies >861 publications with CASP1 and Other Brain Antibodies >544 publications with CASP1 and Brain Bone Antibodies >338 publications with CASP1 and Bone Lung Antibodies >319 publications with CASP1 and Lung Bone Marrow Antibodies >268 publications with CASP1 and Bone Marrow Skin Antibodies >206 publications with CASP1 and Skin Intestine Antibodies >144 publications with CASP1 and Intestine Spleen Antibodies >124 publications with CASP1 and Spleen Lymph Node Antibodies >44 publications with CASP1 and Lymph Node TOP © 2006-24 MyBioSource.com. 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