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F11 elisa kit :: Mouse Coagulation factor XI ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2881535 F11 elisa kit
Unit / Price
48-Strip-Wells  /  $380 +1 FREE 8GB USB
96-Strip-Wells  /  $500 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,170 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,840 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Coagulation factor XI (F11), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Coagulation factor XI ELISA Kit

 Product Synonym Names    Coagulation factor XI; FXI; Plasma thromboplastin antecedent; PTA; F11; 3.4.21.27
 Product Gene Name   

F11 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q91Y47
 Species Reactivity    Mouse
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 Assay Type    Sandwich
 Detection Range    0.312-20 ng/mL
 Sensitivity    0.09 ng/mL
 Intra-Assay CV    <=5.2%
 Inter-Assay CV    <=7.3%
 Recovery    88%
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 Preparation and Storage    For long term storage, please store the entire kit at -20 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of F11 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for F11 purchase    MBS2881535 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Coagulation factor XI (F11) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.312-20 ng/mL in biological research samples containing F11, with an estimated sensitivity of 0.09 ng/mL. The ELISA analytical biochemical technique of the MBS2881535 kit is based on F11 antibody-F11 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect F11 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, F11. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for F11. It may not necessarily be applicable to this product.
 NCBI GI #    21312500
 NCBI GeneID    109821
 NCBI Accession #    NP_082342.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_028066.2 [Other Products]
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 UniProt Primary Accession #    Q91Y47 [Other Products]
 UniProt Secondary Accession #    Q9DAT3 [Other Products]
 UniProt Related Accession #    Q91Y47 [Other Products]
 Molecular Weight    69,789 Da
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 NCBI Official Full Name    coagulation factor XI preproprotein
 NCBI Official Synonym Full Names    coagulation factor XI
 NCBI Official Symbol    F11 [Similar Products]
 NCBI Official Synonym Symbols   
FXI; PTA; Cf11; AI503996; 1600027G01Rik
[Similar Products]
 NCBI Protein Information    coagulation factor XI
 UniProt Protein Name    Coagulation factor XI
 UniProt Synonym Protein Names   
Plasma thromboplastin antecedent; PTA
 Protein Family    Coagulation factor
 UniProt Gene Name    F11 [Similar Products]
 UniProt Synonym Gene Names    FXI; PTA [Similar Products]
 UniProt Entry Name    FA11_MOUSE
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 NCBI Summary for F11    This gene encodes a glycoprotein coagulation factor that plays an important role in intrinsic pathway of blood coagulation and hemostasis. The encoded protein is an inactive zymogen that can be activated by coagulation factor XIIa, thrombin or factor XIa to generate active factor XIa protease. Mice lacking the encoded protein display a survival advantage during peritoneal sepsis and resist inflammation and bacterial accumulation upon infection with Listeria. [provided by RefSeq, Apr 2015]
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 UniProt Comments for F11    F11: Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX. Defects in F11 are the cause of factor XI deficiency (FA11D); also known as plasma thromboplastin antecedent deficiency or Rosenthal syndrome. It is a hemorrhagic disease characterized by reduced levels and activity of factor XI resulting in moderate bleeding symptoms, usually occurring after trauma or surgery. Patients usually do not present spontaneous bleeding but women can present with menorrhagia. Hemorrhages are usually moderate. Belongs to the peptidase S1 family. Plasma kallikrein subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide; EC 3.4.21.27; Protease

Cellular Component: extracellular region; extracellular space

Molecular Function: heparin binding; hydrolase activity; peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity

Biological Process: blood coagulation; hemostasis; plasminogen activation; positive regulation of fibrinolysis; proteolysis; regulation of blood coagulation
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 Research Articles on F11    1. anion-binding sites on FXIa that are required for expression of heparin's cofactor activity during protease inhibition by antithrombin are also required for expression of polyP cofactor activity during FXI activation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with F11 elisa kitPathways associated with F11 elisa kit
 Reference Product  PubMed Publications
 F12 elisa kit  >36 publications with F11 and F12
 Klkb1 elisa kit  >8 publications with F11 and Klkb1
 Kng1 elisa kit  >8 publications with F11 and Kng1
 Serpinc1 elisa kit  >6 publications with F11 and Serpinc1
 Products by Pathway  Pathway Diagram
 Blood Clotting Cascade Pathway antibodies  Blood Clotting Cascade Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Formation Of Fibrin Clot (Clotting Cascade) Pathway antibodies  Formation Of Fibrin Clot (Clotting Cascade) Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Intrinsic Pathway Of Fibrin Clot Formation antibodies  Intrinsic Pathway Of Fibrin Clot Formation Diagram
Diseases associated with F11 elisa kitOrgans/Tissues associated with F11 elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >62 publications with F11 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >50 publications with F11 and Cardiovascular Diseases
 Brain Diseases Antibodies  >37 publications with F11 and Brain Diseases
 Factor XI Deficiency Antibodies  >34 publications with F11 and Factor XI Deficiency
 Inflammation Antibodies  >24 publications with F11 and Inflammation
 Poisoning Antibodies  >14 publications with F11 and Poisoning
 Hypertension Antibodies  >12 publications with F11 and Hypertension
 Heart Diseases Antibodies  >11 publications with F11 and Heart Diseases
 Neurotoxicity Syndromes Antibodies  >11 publications with F11 and Neurotoxicity Syndromes
 Neoplasms, Experimental Antibodies  >9 publications with F11 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >35 publications with F11 and Muscle
 Embryonic Tissue Antibodies  >24 publications with F11 and Embryonic Tissue
 Eye Antibodies  >21 publications with F11 and Eye
 Liver Antibodies  >19 publications with F11 and Liver
 Extraembryonic Tissue Antibodies  >1 publications with F11 and Extraembryonic Tissue
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