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Cr2 elisa kit :: Mouse Complement receptor type 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS289840 Cr2 elisa kit
Unit / Price
48-Strip-Wells  /  $380 +1 FREE 8GB USB
96-Strip-Wells  /  $500 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,170 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,840 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Complement receptor type 2 (Cr2), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Complement receptor type 2 ELISA Kit

 Product Synonym Names    Mus musculus; Cr2; Complement receptor type 2; Cr2; Complement C3d receptor; Cr2; CD21; CD21
 Product Gene Name   

Cr2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P19070
 Species Reactivity    Mouse
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 Assay Type    Sandwich
 Detection Range    0.78-50 ng/mL
 Sensitivity    0.392 ng/mL
 Intra-Assay CV    <=5.5%
 Inter-Assay CV    <=7.9%
 Recovery    98%
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 Preparation and Storage    For long term storage, please store the entire kit at -20 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of Cr2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Cr2 purchase    MBS289840 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Complement receptor type 2 (Cr2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.78-50 ng/mL in biological research samples containing Cr2, with an estimated sensitivity of 0.392 ng/mL. The ELISA analytical biochemical technique of the MBS289840 kit is based on Cr2 antibody-Cr2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Cr2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Cr2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for Cr2. It may not necessarily be applicable to this product.
 NCBI GI #    117316
 NCBI GeneID    12902
 NCBI Accession #    P19070.1 [Other Products]
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 UniProt Primary Accession #    P19070 [Other Products]
 UniProt Related Accession #    P19070 [Other Products]
 Molecular Weight    112,995 Da
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 NCBI Official Full Name    Complement receptor type 2
 NCBI Official Synonym Full Names    complement receptor 2
 NCBI Official Symbol    Cr2 [Similar Products]
 NCBI Official Synonym Symbols   
Cr1; C3DR; CD21; CD35; Cr-1; Cr-2
[Similar Products]
 NCBI Protein Information    complement receptor type 2
 UniProt Protein Name    Complement receptor type 2
 UniProt Synonym Protein Names   
Complement C3d receptor; CD_antigen: CD21
 Protein Family    Complement receptor
 UniProt Gene Name    Cr2 [Similar Products]
 UniProt Synonym Gene Names    Cr2 [Similar Products]
 UniProt Entry Name    CR2_MOUSE
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 UniProt Comments for Cr2    CR2: Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. Genetic variations in CR2 are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a complex genetic basis. SLE is an inflammatory, and often febrile multisystemic disorder of connective tissue characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system. Defects in CR2 are the cause of immunodeficiency, common variable, type 7 (CVID7). A primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low. Belongs to the receptors of complement activation (RCA) family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: external side of plasma membrane; integral to membrane; membrane; receptor complex

Molecular Function: complement binding; complement receptor activity; DNA binding; protein binding; protein homodimerization activity; receptor activity

Biological Process: B cell activation; B cell differentiation; B cell proliferation; complement activation, classical pathway; immune system process; innate immune response
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 Research Articles on Cr2    1. Immunization of Cr1KO mice with a T cell-dependent antigen resulted in the normal initial expansion of B cells with a germinal center phenotype however these cells were preferentially lost in the Cr1KO animal over time (days).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Cr2 elisa kitPathways associated with Cr2 elisa kit
 Reference Product  PubMed Publications
 Cd19 elisa kit  >76 publications with Cr2 and Cd19
 C4b elisa kit  >35 publications with Cr2 and C4b
 Cd81 elisa kit  >16 publications with Cr2 and Cd81
 Cd22 elisa kit  >12 publications with Cr2 and Cd22
 Itgam elisa kit  >5 publications with Cr2 and Itgam
 C1qa elisa kit  >4 publications with Cr2 and C1qa
 Itgax elisa kit  >3 publications with Cr2 and Itgax
 Cd79a elisa kit  >1 publications with Cr2 and Cd79a
 Products by Pathway  Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
Organs/Tissues associated with Cr2 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Spleen Antibodies  >64 publications with Cr2 and Spleen
 Lymph Node Antibodies  >46 publications with Cr2 and Lymph Node
 Thymus Antibodies  >18 publications with Cr2 and Thymus
 Embryonic Tissue Antibodies  >5 publications with Cr2 and Embryonic Tissue
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