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COX2 elisa kit :: Mouse Cyclooxygenase 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS720812
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells-(Competitive)  /  $455 +1 FREE 8GB USB
48-Strip-Wells-(Sandwich)  /  $455 +1 FREE 8GB USB
96-Strip-Wells-(Competitive)  /  $660 +1 FREE 8GB USB
96-Strip-Wells-(Sandwich)  /  $660 +1 FREE 8GB USB
5x96-Strip-Wells-(Competitive)  /  $2,925 +3 FREE 8GB USB
5x96-Strip-Wells-(Sandwich)  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells-(Competitive)  /  $5,490 +6 FREE 8GB USB
10x96-Strip-Wells-(Sandwich)  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cyclooxygenase 2 (COX2), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Cyclooxygenase 2 ELISA Kit

 Product Gene Name   

COX2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Competitive ELISA Manual Insert    Competitive ELISA PDF Manual
  Sandwich ELISA Manual Insert    Sandwich ELISA PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS720812 COA    COA PDF
 OMIM    600262
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 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of COX-2. No significant cross-reactivity or interference between COX-2 and analogues was observed. NOTE: Limited by current skills and knowledge, it is impossible for us to complete the cross-reactivity detection between COX-2 and all the analogues, therefore, cross reaction may still exist in some cases.
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 Samples    Serum, plasma, cell culture supernatants, body fluid and tissue homogenate
 Sensitivity    0.1 ng/mL
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of COX2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for COX2 purchase    MBS720812 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cyclooxygenase 2 (COX2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing COX2, with an estimated sensitivity of 0.1 ng/mL. The ELISA analytical biochemical technique of the MBS720812 kit is based on COX2 antibody-COX2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect COX2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, COX2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, cell culture supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for COX2 elisa kit

   Intended Uses: This COX-2 ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Mouse COX-2. This ELISA kit for research use only, not for therapeutic or diagnostic applications!
 Product Categories/Family for COX2 elisa kit    Cardiovascular
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 Typical Testing Data/Standard Curve (for reference only) of COX2 elisa kit    COX2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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NCBI/Uniprot data below describe general gene information for COX2. It may not necessarily be applicable to this product.
 NCBI GI #    181254
 NCBI GeneID    5743
 NCBI Accession #    AAA58433.1 [Other Products]
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 UniProt Secondary Accession #    Q16876; A8K802 [Other Products]
 UniProt Related Accession #    P35354 [Other Products]
 Molecular Weight    68,996 Da
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 NCBI Official Full Name    cyclooxygenase-2
 NCBI Official Synonym Full Names    prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
 NCBI Official Symbol    PTGS2 [Similar Products]
 NCBI Official Synonym Symbols   
COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS
[Similar Products]
 NCBI Protein Information    prostaglandin G/H synthase 2; PHS II; PGH synthase 2; cyclooxygenase 2b; prostaglandin H2 synthase 2
 UniProt Protein Name    Prostaglandin G/H synthase 2
 UniProt Synonym Protein Names   
Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
 UniProt Gene Name    PTGS2 [Similar Products]
 UniProt Synonym Gene Names    COX2; COX-2; PGH synthase 2; PGHS-2 [Similar Products]
 UniProt Entry Name    PGH2_HUMAN
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 NCBI Summary for COX2    Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
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 UniProt Comments for COX2    COX-2: Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity. Homodimer. Belongs to the prostaglandin G/H synthase family.

Protein type: EC 1.14.99.1; Oxidoreductase; Lipid Metabolism - arachidonic acid

Chromosomal Location of Human Ortholog: 1q25.2-q25.3

Cellular Component: endoplasmic reticulum membrane; neuron projection; protein complex; cytoplasm; caveola; nucleus

Molecular Function: prostaglandin-endoperoxide synthase activity; protein homodimerization activity; enzyme binding; peroxidase activity; arachidonate 15-lipoxygenase activity; metal ion binding; heme binding; lipid binding

Biological Process: positive regulation of nitric oxide biosynthetic process; positive regulation of apoptosis; response to lithium ion; positive regulation of smooth muscle cell proliferation; response to glucocorticoid stimulus; positive regulation of NF-kappaB import into nucleus; response to lipopolysaccharide; decidualization; sensory perception of pain; prostaglandin biosynthetic process; negative regulation of synaptic transmission, dopaminergic; positive regulation of synaptic transmission, glutamatergic; response to estradiol stimulus; bone mineralization; negative regulation of cell cycle; negative regulation of cell proliferation; response to vitamin D; lipoxygenase pathway; nicotinamide metabolic process; negative regulation of smooth muscle contraction; regulation of blood pressure; arachidonic acid metabolic process; angiogenesis; positive regulation of smooth muscle contraction; inflammatory response; response to fructose stimulus; water-soluble vitamin metabolic process; positive regulation of prostaglandin biosynthetic process; response to drug; negative regulation of calcium ion transport; vitamin metabolic process; cyclooxygenase pathway; positive regulation of synaptic plasticity; learning; memory; prostaglandin metabolic process; hair cycle; ovulation; response to manganese ion; NAD metabolic process; regulation of inflammatory response; positive regulation of vasoconstriction; brown fat cell differentiation; positive regulation of fever; response to oxidative stress; cell motility; embryo implantation
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 Research Articles on COX2    1. Hydroxytyrosol, at nutritionally relevant concentrations, reduces MMP-9 and COX-2 induction in activated human monocytes via PKCalpha and PKCbeta1 inhibition
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with COX2 elisa kitPathways associated with COX2 elisa kit
 Reference Product  PubMed Publications
 JUN elisa kit  >2734 publications with COX2 and JUN
 PLA2G4A elisa kit  >298 publications with COX2 and PLA2G4A
 ALOX5 elisa kit  >273 publications with COX2 and ALOX5
 MAPK1 elisa kit  >254 publications with COX2 and MAPK1
 FOS elisa kit  >231 publications with COX2 and FOS
 PTGES elisa kit  >46 publications with COX2 and PTGES
 CYP2E1 elisa kit  >34 publications with COX2 and CYP2E1
 MAPK14 elisa kit  >8 publications with COX2 and MAPK14
 PTGDS elisa kit  >6 publications with COX2 and PTGDS
 PLA2G1B elisa kit  >3 publications with COX2 and PLA2G1B
 Products by Pathway  Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram
 C20 Prostanoid Biosynthesis Pathway antibodies  C20 Prostanoid Biosynthesis Pathway Diagram
 Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies  Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
 Calcium Signaling In The CD4+ TCR Pathway antibodies  Calcium Signaling In The CD4+ TCR Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway antibodies  Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway Diagram
Diseases associated with COX2 elisa kitOrgans/Tissues associated with COX2 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >6224 publications with COX2 and Inflammation
 Carcinoma Antibodies  >3031 publications with COX2 and Carcinoma
 Nervous System Diseases Antibodies  >2206 publications with COX2 and Nervous System Diseases
 Colorectal Neoplasms Antibodies  >1685 publications with COX2 and Colorectal Neoplasms
 Adenocarcinoma Antibodies  >1437 publications with COX2 and Adenocarcinoma
 Skin Diseases Antibodies  >1149 publications with COX2 and Skin Diseases
 Lung Diseases Antibodies  >1011 publications with COX2 and Lung Diseases
 Colonic Neoplasms Antibodies  >952 publications with COX2 and Colonic Neoplasms
 Edema Antibodies  >897 publications with COX2 and Edema
 Breast Neoplasms Antibodies  >732 publications with COX2 and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4660 publications with COX2 and Blood
 Vascular Antibodies  >3122 publications with COX2 and Vascular
 Brain Antibodies  >1991 publications with COX2 and Brain
 Lung Antibodies  >1554 publications with COX2 and Lung
 Liver Antibodies  >1375 publications with COX2 and Liver
 Muscle Antibodies  >1367 publications with COX2 and Muscle
 Kidney Antibodies  >1231 publications with COX2 and Kidney
 Stomach Antibodies  >1207 publications with COX2 and Stomach
 Bone Antibodies  >1152 publications with COX2 and Bone
 Intestine Antibodies  >1019 publications with COX2 and Intestine
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