Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow DDIT4 rightarrow Mouse DDIT4  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • 40S ribosomal protein S10 (RPS10) Antibody
 • Protein A, S. aureus, Cowan Strain Reagent
 • Follicle Stimulating Hormone (FSH) ELISA Kit
 • E-Selectin ELISA Kit
 • NGF ELISA Kit
 • ALDH2 Antibody
 • N-Acetyl Beta-D-Glucosaminidase (NAGase) ELISA Kit
 • Dual specificity protein phosphatase 7 (DUSP7) Antibody
 • cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibit... ELISA Kit
 • ATP synthase subunit beta (Atp5b) Recombinant Protein
 • IFN gamma (IFNG) ELISA Kit
 • Rubella, Capsid Protein Recombinant Protein
 • Thy1 Cell Surface Antigen (Thy1) ELISA Kit
 • RASSF6 (RASSF6 ) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

DDIT4 elisa kit :: Mouse DNA Damage-Inducible Transcript 4 (DDIT4) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9354284 DDIT4 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DNA Damage-Inducible Transcript 4 (DDIT4), ELISA Kit

★Popular Item★
 Also Known As   

Mouse DNA Damage-Inducible Transcript 4 (DDIT4) ELISA Kit

 Product Gene Name   

DDIT4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    607729
Section Bar
 Species Reactivity    Mouse
Section Bar
 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
Section Bar
 Samples    undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples
 Assay Type    Quantitative Sandwich
 Detection Range    0.625 ng/ml - 20 ng/mL
 Sensitivity    0.1 ng/mL
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
Section Bar
 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of DDIT4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for DDIT4 purchase    MBS9354284 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the DNA Damage-Inducible Transcript 4 (DDIT4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.625 ng/ml - 20 ng/mL in biological research samples containing DDIT4, with an estimated sensitivity of 0.1 ng/mL. The ELISA analytical biochemical technique of the MBS9354284 kit is based on DDIT4 antibody-DDIT4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DDIT4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DDIT4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
 

Related Product Information for DDIT4 elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of DDIT4 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9354284. Click to request current manual
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for DDIT4. It may not necessarily be applicable to this product.
 NCBI GI #    9506687
 NCBI GeneID    54541
 NCBI Accession #    NP_061931.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_019058.2 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q9H0S3 [Other Products]
 UniProt Related Accession #    Q9NX09 [Other Products]
 Molecular Weight    25,371 Da
Table BarTOPTable Bar
 NCBI Official Full Name    DNA damage-inducible transcript 4 protein
 NCBI Official Synonym Full Names    DNA damage inducible transcript 4
 NCBI Official Symbol    DDIT4 [Similar Products]
 NCBI Official Synonym Symbols   
Dig2; REDD1; REDD-1
[Similar Products]
 NCBI Protein Information    DNA damage-inducible transcript 4 protein
 UniProt Protein Name    DNA damage-inducible transcript 4 protein
 UniProt Synonym Protein Names   
HIF-1 responsive protein RTP801; Protein regulated in development and DNA damage response 1; REDD-1
 Protein Family    DNA damage-inducible transcript 4 protein
 UniProt Gene Name    DDIT4 [Similar Products]
 UniProt Synonym Gene Names    REDD1; RTP801; REDD-1 [Similar Products]
 UniProt Entry Name    DDIT4_HUMAN
Section Bar
 UniProt Comments for DDIT4    DDIT4: Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Promotes neuronal cell death. Up-regulated in fibroblasts upon ionizing radiation, via a TP53-dependent pathway. Up-regulated by TP63 in primary keratinocytes, and down-regulated during keratinocyte differentiation. Up-regulated upon DNA alkylation. Up-regulated by amyloid beta-peptide and retinoic acid. Up-regulated by hypoxia, via a PI3K and HIF1A-dependent but TP53/TP63-independent mechanism. Broadly expressed, with lowest levels in brain, skeletal muscle and intestine. Up-regulated in substantia nigra neurons from Parkinson disease patients. Belongs to the DDIT4 family.

Chromosomal Location of Human Ortholog: 10q22.1

Cellular Component: cytoplasm; cytosol; intracellular; mitochondrion

Biological Process: brain development; cell proliferation; defense response to virus; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; gene expression; negative regulation of glycolysis; negative regulation of peptidyl-serine phosphorylation; negative regulation of TOR signaling pathway; nerve growth factor receptor signaling pathway; neuron differentiation; neuron migration; protein complex disassembly; response to hypoxia; transcription initiation from RNA polymerase II promoter
Table BarTOPTable Bar
 Research Articles on DDIT4    1. Findings from this study propose a REDD1-regulated mechanism in T2D skeletal muscle that may contribute to whole body insulin resistance and may be a target to improve insulin action in insulin-resistant individuals.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with DDIT4 elisa kitPathways associated with DDIT4 elisa kit
 Reference Product  PubMed Publications
 MTOR elisa kit  >86 publications with DDIT4 and MTOR
 TSC2 elisa kit  >23 publications with DDIT4 and TSC2
 TSC1 elisa kit  >18 publications with DDIT4 and TSC1
 TP53 elisa kit  >4 publications with DDIT4 and TP53
 Products by Pathway  Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 TOR Signaling Pathway antibodies  TOR Signaling Pathway Diagram
 TP53 Regulates Metabolic Genes Pathway antibodies  TP53 Regulates Metabolic Genes Pathway Diagram
 Transcriptional Regulation By TP53 Pathway antibodies  Transcriptional Regulation By TP53 Pathway Diagram
Diseases associated with DDIT4 elisa kitOrgans/Tissues associated with DDIT4 elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >15 publications with DDIT4 and Nervous System Diseases
 Disease Models, Animal Antibodies  >14 publications with DDIT4 and Disease Models, Animal
 Brain Diseases Antibodies  >12 publications with DDIT4 and Brain Diseases
 Breast Neoplasms Antibodies  >11 publications with DDIT4 and Breast Neoplasms
 Cardiovascular Diseases Antibodies  >10 publications with DDIT4 and Cardiovascular Diseases
 Leukemia Antibodies  >9 publications with DDIT4 and Leukemia
 Lung Neoplasms Antibodies  >6 publications with DDIT4 and Lung Neoplasms
 Inflammation Antibodies  >5 publications with DDIT4 and Inflammation
 Liver Diseases Antibodies  >5 publications with DDIT4 and Liver Diseases
 Parkinson Disease Antibodies  >4 publications with DDIT4 and Parkinson Disease
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >24 publications with DDIT4 and Muscle
 Blood Antibodies  >22 publications with DDIT4 and Blood
 Brain Antibodies  >18 publications with DDIT4 and Brain
 Liver Antibodies  >14 publications with DDIT4 and Liver
 Lung Antibodies  >11 publications with DDIT4 and Lung
 Bone Antibodies  >8 publications with DDIT4 and Bone
 Prostate Antibodies  >6 publications with DDIT4 and Prostate
 Heart Antibodies  >5 publications with DDIT4 and Heart
 Nerve Antibodies  >5 publications with DDIT4 and Nerve
 Placenta Antibodies  >4 publications with DDIT4 and Placenta
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions