NP_031887.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
54,272 Da
NCBI Official Full Name
dihydrolipoyl dehydrogenase, mitochondrial
NCBI Official Synonym Full Names
dihydrolipoamide dehydrogenase
NCBI Protein Information
dihydrolipoyl dehydrogenase, mitochondrial
UniProt Protein Name
Dihydrolipoyl dehydrogenase, mitochondrial
UniProt Synonym Protein Names
Dihydrolipoamide dehydrogenase
NCBI Summary for DLD
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. [provided by RefSeq, Jan 2014]
UniProt Comments for DLD
Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of the alpha-ketoacid dehydrogenase complexes (pyruvate-, alpha-ketoglutarate-, and branched-chain amino acid-dehydrogenase complex). In monomeric form has additional moonlighting function as serine protease (PubMed:17404228). Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction ().
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Products associated with DLD elisa kit
Pathways associated with DLD elisa kit
Diseases associated with DLD elisa kit
Organs/Tissues associated with DLD elisa kit
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