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EVC elisa kit :: Mouse Ellis van Creveld syndrome ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9334534 EVC elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Ellis van Creveld syndrome (EVC), ELISA Kit

 Also Known As   

Mouse Ellis-van Creveld syndrome protein, EVC ELISA Kit

 Product Synonym Names    Mouse Ellis-van Creveld syndrome protein (EVC) ELISA kit; DWF-1; EVC1; EVCL; MGC105107; Ellis van Creveld syndrome protein; Ellis van Creveld syndrome
 Product Gene Name   

EVC elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P57680
 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of EVC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for EVC purchase    MBS9334534 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Ellis van Creveld syndrome (EVC) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing EVC. The ELISA analytical biochemical technique of the MBS9334534 kit is based on EVC antibody-EVC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect EVC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, EVC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for EVC. It may not necessarily be applicable to this product.
 NCBI GI #    269784715
 NCBI GeneID    59056
 NCBI Accession #    NP_067267.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_021292.2 [Other Products]
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 UniProt Primary Accession #    P57680 [Other Products]
 UniProt Secondary Accession #    E9QPK2 [Other Products]
 UniProt Related Accession #    P57680 [Other Products]
 Molecular Weight    113,003 Da
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 NCBI Official Full Name    ellis-van Creveld syndrome protein homolog
 NCBI Official Synonym Full Names    Ellis van Creveld gene syndrome
 NCBI Official Symbol    Evc [Similar Products]
 NCBI Protein Information    ellis-van Creveld syndrome protein homolog; Ellis van Creveld gene homolog; EvC protein (Ellis-van Creveld syndrome)
 UniProt Protein Name    Ellis-van Creveld syndrome protein homolog
 Protein Family    Ellis-van Creveld syndrome protein
 UniProt Gene Name    Evc [Similar Products]
 UniProt Entry Name    EVC_MOUSE
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 UniProt Comments for EVC    EVC: Acts as a positive mediator of Hedgehog signaling indispensable for normal endochondral growth and skeletal development. Defects in EVC are a cause of Ellis-van Creveld syndrome (EVC); also known as chondroectodermal dysplasia. EVC is an autosomal recessive disorder characterized by the clinical tetrad of chondrodystrophy, polydactyly, ectodermal dysplasia and cardiac anomalies. Patients manifest short-limb dwarfism, short ribs, postaxial polydactyly and dysplastic nails and teeth. Congenital heart defects, most commonly an atrioventricular septal defect, are observed in 60% of affected individuals. Defects in EVC are a cause of acrofacial dysostosis Weyers type (WAD); also known as Curry-Hall syndrome. Acrofacial dysostoses are a heterogeneous group of disorders combining limb defects with facial abnormalities. WAD is an autosomal dominant disorder characterized by dysplastic nails, postaxial polydactyly, acrofacial dysostosis, short limbs and short stature. The phenotype is milder than Ellis-van Creveld syndrome.

Protein type: Membrane protein, integral

Cellular Component: cell projection; cytoskeleton; membrane; cytoplasm; integral to membrane; plasma membrane; cilium

Molecular Function: protein binding

Biological Process: smoothened signaling pathway; positive regulation of smoothened signaling pathway
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 Research Articles on EVC    1. it is proposed that Hedgehog activates Smo by inducing its phosphorylation, which recruits Evc/Evc2 to activate Gli proteins by antagonizing Sufu in the primary cilia
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with EVC elisa kitDiseases associated with EVC elisa kit
 Reference Product  PubMed Publications
 Evc2 elisa kit  >36 publications with EVC and Evc2
 Stk32b elisa kit  >2 publications with EVC and Stk32b
 Disease Name  Pubmed Publications
 Ellis-Van Creveld Syndrome Antibodies  >79 publications with EVC and Ellis-Van Creveld Syndrome
 Congenital Abnormalities Antibodies  >76 publications with EVC and Congenital Abnormalities
 Heart Diseases Antibodies  >25 publications with EVC and Heart Diseases
 Heart Defects, Congenital Antibodies  >18 publications with EVC and Heart Defects, Congenital
 Nervous System Diseases Antibodies  >11 publications with EVC and Nervous System Diseases
 Disease Models, Animal Antibodies  >10 publications with EVC and Disease Models, Animal
 Heart Failure Antibodies  >6 publications with EVC and Heart Failure
 Central Nervous System Diseases Antibodies  >5 publications with EVC and Central Nervous System Diseases
 Inflammation Antibodies  >5 publications with EVC and Inflammation
 Liver Diseases Antibodies  >5 publications with EVC and Liver Diseases
Organs/Tissues associated with EVC elisa kit
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >16 publications with EVC and Bone
 Brain Antibodies  >9 publications with EVC and Brain
 Lung Antibodies  >8 publications with EVC and Lung
 Kidney Antibodies  >5 publications with EVC and Kidney
 Skin Antibodies  >3 publications with EVC and Skin
 Pancreas Antibodies  >2 publications with EVC and Pancreas
 Embryonic Tissue Antibodies  >2 publications with EVC and Embryonic Tissue
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