P49891.2
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
35,590 Da
NCBI Official Full Name
Estrogen sulfotransferase, testis isoform
NCBI Official Synonym Full Names
sulfotransferase family 1E, member 1
NCBI Protein Information
estrogen sulfotransferase, testis isoform
UniProt Protein Name
Estrogen sulfotransferase, testis isoform
UniProt Synonym Protein Names
Sulfotransferase 1E1; ST1E1; Sulfotransferase, estrogen-preferring
UniProt Synonym Gene Names
UniProt Entry Name
ST1E1_MOUSE
UniProt Comments for Sult1e1
SULT1E1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol. Maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. Also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations; however, cortisol, testosterone and dopamine are not sulfated. Belongs to the sulfotransferase 1 family.
Protein type: Transferase; Energy Metabolism - sulfur; Lipid Metabolism - androgen and estrogen; EC 2.8.2.4
Cellular Component: cytoplasm
Molecular Function: 1-phenanthrol sulfotransferase activity; 2-phenanthrol sulfotransferase activity; 3-phenanthrol sulfotransferase activity; 4-phenanthrol sulfotransferase activity; 9-phenanthrol sulfotransferase activity; cholesterol sulfotransferase activity; estrone sulfotransferase activity; flavonol 3-sulfotransferase activity; galactose 3-O-sulfotransferase activity; heparan sulfate 2-O-sulfotransferase activity; heparan sulfate 6-O-sulfotransferase activity; HNK-1 sulfotransferase activity; lipid binding; N-acetylgalactosamine 4-O-sulfotransferase activity; N-acetylglucosamine 6-O-sulfotransferase activity; phenanthrol sulfotransferase activity; proteoglycan sulfotransferase activity; steroid binding; steroid sulfotransferase activity; sulfotransferase activity; trans-3,4-dihydrodiolphenanthrene sulfotransferase activity; trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity; transferase activity
Biological Process: estrogen metabolic process; female pregnancy; positive regulation of fat cell differentiation; sulfation
Research Articles on Sult1e1
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Products associated with Sult1e1 elisa kit
Pathways associated with Sult1e1 elisa kit
Organs/Tissues associated with Sult1e1 elisa kit
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