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FGbeta elisa kit :: Mouse Fibrinogen Beta ELISA Kit

Scan QR to view Datasheet Catalog #    MBS730082
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Fibrinogen Beta (FGbeta), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Fibrinogen Beta ELISA Kit

 Product Gene Name   

FGbeta elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 202400
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 Species Reactivity    Mouse
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    5.0-100ng/mL
 Sensitivity    1.0ng/mL
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FGbeta elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FGbeta purchase    MBS730082 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Fibrinogen Beta (FGbeta) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 5.0-100ng/mL in biological research samples containing FGbeta, with an estimated sensitivity of 1.0ng/mL. The ELISA analytical biochemical technique of the MBS730082 kit is based on FGbeta antibody-FGbeta antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FGbeta antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FGbeta. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for FGbeta elisa kit    Cardiovascular
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 Typical Testing Data/Standard Curve (for reference only) of FGbeta elisa kit    FGbeta elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS730082. Click to request current manual
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NCBI/Uniprot data below describe general gene information for FGbeta. It may not necessarily be applicable to this product.
 NCBI GI #    70906435
 NCBI GeneID    2244
 NCBI Accession #    NP_005132.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_005141.4 [Other Products]
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 UniProt Secondary Accession #    Q32Q65; Q3KPF2; A0JLR9; B2R7G3 [Other Products]
 UniProt Related Accession #    P02675 [Other Products]
 Molecular Weight    55,928 Da
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 NCBI Official Full Name    fibrinogen beta chain isoform 1 preproprotein
 NCBI Official Synonym Full Names    fibrinogen beta chain
 NCBI Official Symbol    FGB [Similar Products]
 NCBI Official Synonym Symbols   
HEL-S-78p
[Similar Products]
 NCBI Protein Information    fibrinogen beta chain; fibrinogen, B beta polypeptide; epididymis secretory sperm binding protein Li 78p
 UniProt Protein Name    Fibrinogen beta chain
 Protein Family    Fibrinogen
 UniProt Gene Name    FGB [Similar Products]
 UniProt Entry Name    FIBB_HUMAN
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 NCBI Summary for FGbeta    The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
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 UniProt Comments for FGbeta    FGB: Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation. Defects in FGB are a cause of congenital afibrinogenemia (CAFBN). This rare autosomal recessive disorder is characterized by bleeding that varies from mild to severe and by complete absence or extremely low levels of plasma and platelet fibrinogen. Patients with congenital fibrinogen abnormalities can manifest different clinical pictures. Some cases are clinically silent, some show a tendency toward bleeding and some show a predisposition for thrombosis with or without bleeding.

Protein type: Adaptor/scaffold; Secreted; Cell surface; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q28

Cellular Component: extracellular space; cell surface; fibrinogen complex; extracellular region; plasma membrane; cell cortex; vesicle; external side of plasma membrane

Molecular Function: protein binding, bridging; protein binding; chaperone binding; cell adhesion molecule binding; structural molecule activity; receptor binding

Biological Process: protein polymerization; platelet activation; extracellular matrix organization and biogenesis; positive regulation of heterotypic cell-cell adhesion; cell-matrix adhesion; signal transduction; platelet degranulation; cellular protein complex assembly; positive regulation of protein secretion; positive regulation of vasoconstriction; innate immune response; blood coagulation; response to calcium ion; positive regulation of exocytosis

Disease: Afibrinogenemia, Congenital; Dysfibrinogenemia, Congenital
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 Research Articles on FGbeta    1. Both fibrinogen polymorphisms are capable to modify the atherosclerotic process via their effects on the coagulation cascade.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FGbeta elisa kitPathways associated with FGbeta elisa kit
 Reference Product  PubMed Publications
 FGA elisa kit  >82 publications with FGbeta and FGA
 FGG elisa kit  >74 publications with FGbeta and FGG
 ITGB3 elisa kit  >13 publications with FGbeta and ITGB3
 F13A1 elisa kit  >5 publications with FGbeta and F13A1
 FGL1 elisa kit  >1 publications with FGbeta and FGL1
 Products by Pathway  Pathway Diagram
 Blood Clotting Cascade Pathway antibodies  Blood Clotting Cascade Pathway Diagram
 Common Pathway antibodies  Common Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Formation Of Fibrin Clot (Clotting Cascade) Pathway antibodies  Formation Of Fibrin Clot (Clotting Cascade) Pathway Diagram
 GRB2:SOS Provides Linkage To MAPK Signaling For Integrins Pathway antibodies  GRB2:SOS Provides Linkage To MAPK Signaling For Integrins Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Integrin AlphaIIb Beta3 Signaling Pathway antibodies  Integrin AlphaIIb Beta3 Signaling Pathway Diagram
Diseases associated with FGbeta elisa kitOrgans/Tissues associated with FGbeta elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >69 publications with FGbeta and Cardiovascular Diseases
 Afibrinogenemia congenital Antibodies  >47 publications with FGbeta and Afibrinogenemia congenital
 Thrombosis Antibodies  >24 publications with FGbeta and Thrombosis
 Brain Diseases Antibodies  >22 publications with FGbeta and Brain Diseases
 Inflammation Antibodies  >19 publications with FGbeta and Inflammation
 Atherosclerosis Antibodies  >11 publications with FGbeta and Atherosclerosis
 Kidney Diseases Antibodies  >5 publications with FGbeta and Kidney Diseases
 Liver Diseases Antibodies  >3 publications with FGbeta and Liver Diseases
 Hypercholesterolemia Antibodies  >3 publications with FGbeta and Hypercholesterolemia
 Hyperlipidemias Antibodies  >2 publications with FGbeta and Hyperlipidemias
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >98 publications with FGbeta and Blood
 Heart Antibodies  >16 publications with FGbeta and Heart
 Liver Antibodies  >12 publications with FGbeta and Liver
 Brain Antibodies  >9 publications with FGbeta and Brain
 Lung Antibodies  >9 publications with FGbeta and Lung
 Muscle Antibodies  >5 publications with FGbeta and Muscle
 Kidney Antibodies  >5 publications with FGbeta and Kidney
 Bladder Antibodies  >2 publications with FGbeta and Bladder
 Pancreas Antibodies  >1 publications with FGbeta and Pancreas
 Intestine Antibodies  >1 publications with FGbeta and Intestine
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