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GRK4 elisa kit :: Mouse G protein-coupled receptor kinase 4 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9337263 GRK4 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

G protein-coupled receptor kinase 4 (GRK4), ELISA Kit

 Also Known As   

Mouse G protein-coupled receptor kinase 4, GRK4 ELISA Kit

 Product Synonym Names    Mouse G protein-coupled receptor kinase 4 (GRK4) ELISA kit; GPRK2L; GPRK4; GRK4a; IT11; G protein-coupled receptor kinase 2-like; G-protein coupled receptor kinase 4; G protein-coupled receptor kinase 4
 Product Gene Name   

GRK4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for O70291
 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of GRK4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GRK4 purchase    MBS9337263 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the G protein-coupled receptor kinase 4 (GRK4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GRK4. The ELISA analytical biochemical technique of the MBS9337263 kit is based on GRK4 antibody-GRK4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GRK4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GRK4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for GRK4. It may not necessarily be applicable to this product.
 NCBI GI #    124001566
 NCBI GeneID    14772
 NCBI Accession #    NP_001074212.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001080743.1 [Other Products]
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 UniProt Primary Accession #    O70291 [Other Products]
 UniProt Secondary Accession #    Q3V151 [Other Products]
 UniProt Related Accession #    O70291 [Other Products]
 Molecular Weight    66,928 Da
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 NCBI Official Full Name    G protein-coupled receptor kinase 4 isoform 2
 NCBI Official Synonym Full Names    G protein-coupled receptor kinase 4
 NCBI Official Symbol    Grk4 [Similar Products]
 NCBI Official Synonym Symbols   
GRK; Gprk4; Gprk2l; A830025H08Rik
[Similar Products]
 NCBI Protein Information    G protein-coupled receptor kinase 4; g protein-coupled receptor kinase GRK4; G protein-coupled receptor kinase 2, groucho gene related
 UniProt Protein Name    G protein-coupled receptor kinase 4
 UniProt Synonym Protein Names   
G protein-coupled receptor kinase GRK4
 Protein Family    G protein-coupled receptor kinase
 UniProt Gene Name    Grk4 [Similar Products]
 UniProt Synonym Gene Names    Gprk2l [Similar Products]
 UniProt Entry Name    GRK4_MOUSE
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 UniProt Comments for GRK4    GRK4: Specifically phosphorylates the activated forms of G protein-coupled receptors. GRK4-alpha can phosphorylate rhodopsin and its activity is inhibited by calmodulin; the other three isoforms do not phosphorylate rhodopsin and do not interact with calmodulin. GRK4-alpha and GRK4-gamma phosphorylate DRD3. Phosphorylates ADRB2. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.16; AGC group; GRK family; GRK subfamily

Cellular Component: cell soma; dendrite; cytoplasm; cytosol

Molecular Function: transferase activity; protein serine/threonine kinase activity; G-protein coupled receptor kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; rhodopsin kinase activity; kinase activity; ATP binding; protein kinase activity

Biological Process: desensitization of G-protein coupled receptor protein signaling pathway; G-protein coupled receptor internalization; receptor internalization; signal transduction; phosphorylation; protein amino acid phosphorylation
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 Research Articles on GRK4    1. GRK2 inhibits WNT signaling in osteoblasts
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with GRK4 elisa kitDiseases associated with GRK4 elisa kit
 Products by Pathway  Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Morphine Addiction Pathway antibodies  Morphine Addiction Pathway Diagram
 Morphine Addiction Pathway antibodies  Morphine Addiction Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Disease Name  Pubmed Publications
 Hypertension Antibodies  >41 publications with GRK4 and Hypertension
 Cardiovascular Diseases Antibodies  >29 publications with GRK4 and Cardiovascular Diseases
 Neoplasms Antibodies  >5 publications with GRK4 and Neoplasms
 Heart Failure Antibodies  >3 publications with GRK4 and Heart Failure
 Heart Diseases Antibodies  >3 publications with GRK4 and Heart Diseases
 Kidney Diseases Antibodies  >3 publications with GRK4 and Kidney Diseases
 Proteinuria Antibodies  >2 publications with GRK4 and Proteinuria
 Nervous System Diseases Antibodies  >1 publications with GRK4 and Nervous System Diseases
 Prostatic Diseases Antibodies  >1 publications with GRK4 and Prostatic Diseases
 Hyperplasia Antibodies  >1 publications with GRK4 and Hyperplasia
Organs/Tissues associated with GRK4 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >6 publications with GRK4 and Eye
 Brain Antibodies  >6 publications with GRK4 and Brain
 Testis Antibodies  >4 publications with GRK4 and Testis
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