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GFRA2 elisa kit :: Mouse GDNF family receptor alpha 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9329344 GFRA2 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GDNF family receptor alpha 2 (GFRA2), ELISA Kit

 Also Known As   

Mouse GDNF family receptor alpha-2, GFRA2 ELISA Kit

 Product Synonym Names    Mouse GDNF family receptor alpha-2 (GFRA2) ELISA kit; GDNFRB; NRTNR-ALPHA; NTNRA; RETL2; TRNR2; GFR-alpha 2; PI-linked cell-surface accessory protein; RET ligand 2; TGF-beta related neurotrophic factor receptor 2; TRN receptor; GPI-anchored; glial cell line; GDNF family receptor alpha 2
 Product Gene Name   

GFRA2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 3D Structure    ModBase 3D Structure for O08842
 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Other Notes    Small volumes of GFRA2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GFRA2 purchase    MBS9329344 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the GDNF family receptor alpha 2 (GFRA2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GFRA2. The ELISA analytical biochemical technique of the MBS9329344 kit is based on GFRA2 antibody-GFRA2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GFRA2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GFRA2. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for GFRA2. It may not necessarily be applicable to this product.
 NCBI GI #    84662783
 NCBI GeneID    14586
 NCBI Accession #    NP_032141.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_008115.2 [Other Products]
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 UniProt Primary Accession #    O08842 [Other Products]
 UniProt Secondary Accession #    Q3UUD8 [Other Products]
 UniProt Related Accession #    O08842 [Other Products]
 Molecular Weight    51,727 Da
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 NCBI Official Full Name    GDNF family receptor alpha-2
 NCBI Official Synonym Full Names    glial cell line derived neurotrophic factor family receptor alpha 2
 NCBI Official Symbol    Gfra2 [Similar Products]
 NCBI Protein Information    GDNF family receptor alpha-2; GDNFR-beta; NTNR-alpha; GFR alpha 2; GFR alpha-2; GFR-alpha-2; NRTNR-alpha; GDNFR-alpha-2; GDNF receptor beta; GDNF receptor alpha-2; neurturin receptor alpha; TGF-beta-related neurotrophic factor receptor 2
 UniProt Protein Name    GDNF family receptor alpha-2
 UniProt Synonym Protein Names   
GDNF receptor beta; GDNFR-beta; Neurturin receptor alpha; NRTNR-alpha; NTNR-alpha; TGF-beta-related neurotrophic factor receptor 2
 Protein Family    GDNF family receptor
 UniProt Gene Name    Gfra2 [Similar Products]
 UniProt Synonym Gene Names    Gdnfrb; Trnr2; GDNF receptor alpha-2; GDNFR-alpha-2; GFR-alpha-2; GDNFR-beta; NRTNR-alpha; NTNR-alpha [Similar Products]
 UniProt Entry Name    GFRA2_MOUSE
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 NCBI Summary for GFRA2    The protein encoded by this gene is part of the receptor complex that transduces glial cell-derived neurotrophic factor and neurturin signals by mediating autophosphorylation and activation of the RET receptor. Mice lacking this protein are viable and fertile but display growth retardation attributed to impaired salivary and pancreatic secretion and innervation deficits in the intestinal tract. In addition, knockout mice display neural defects including a failure to initiate outgrowth of dorsal ganglion root neurons, demonstrating a requirement in neuronal differentiation of these cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
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 UniProt Comments for GFRA2    GFRA2: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. Belongs to the GDNFR family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor

Cellular Component: membrane; plasma membrane

Molecular Function: receptor activity; glial cell line-derived neurotrophic factor receptor activity

Biological Process: nervous system development; cytokine and chemokine mediated signaling pathway; negative regulation of protein amino acid autophosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway
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 Research Articles on GFRA2    1. STAT3 phosphorylation by neurturin was found to be mediated specifically by GFRalpha2c and RET9 isoforms.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GFRA2 elisa kitPathways associated with GFRA2 elisa kit
 Reference Product  PubMed Publications
 FLNA elisa kit  >12 publications with GFRA2 and FLNA
 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
Organs/Tissues associated with GFRA2 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >49 publications with GFRA2 and Brain
 Embryonic Tissue Antibodies  >15 publications with GFRA2 and Embryonic Tissue
 Spinal Cord Antibodies  >12 publications with GFRA2 and Spinal Cord
 Eye Antibodies  >11 publications with GFRA2 and Eye
 Blood Antibodies  >9 publications with GFRA2 and Blood
 Sympathetic Ganglion Antibodies  >7 publications with GFRA2 and Sympathetic Ganglion
 Testis Antibodies  >2 publications with GFRA2 and Testis
 Thymus Antibodies  >1 publications with GFRA2 and Thymus
 Lung Antibodies  >1 publications with GFRA2 and Lung
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