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GSTt1 elisa kit :: Mouse GSTt1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2508373
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GSTt1, ELISA Kit

★Popular Item★
 Also Known As   

Mouse GSTt1 (Glutathione S Transferase Theta 1) ELISA Kit

 Product Gene Name   

GSTt1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    600436
 3D Structure    ModBase 3D Structure for P30711
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 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Mouse GSTt1. No significant cross-reactivity or interference between Mouse GSTt1 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Mouse GSTt1 and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.156--10ng/mL
 Sensitivity    0.094ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of GSTt1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GSTt1 purchase    MBS2508373 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the GSTt1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156--10ng/mL in biological research samples containing GSTt1, with an estimated sensitivity of 0.094ng/mL. The ELISA analytical biochemical technique of the MBS2508373 kit is based on GSTt1 antibody-GSTt1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GSTt1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GSTt1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for GSTt1 elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of GSTt1 in Mouse serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse GSTt1. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Mouse GSTt1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse GSTt1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Mouse GSTt1. You can calculate the concentration of Mouse GSTt1 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of GSTt1 elisa kit    GSTt1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2508373. Click to request current manual
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NCBI/Uniprot data below describe general gene information for GSTt1. It may not necessarily be applicable to this product.
 NCBI GI #    167466164
 NCBI GeneID    2952
 NCBI Accession #    NP_000844.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000853.3 [Other Products]
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 UniProt Primary Accession #    P30711 [Other Products]
 UniProt Secondary Accession #    O00226; Q5TZY2; Q6IC69; Q969K8; Q96IY3 [Other Products]
 UniProt Related Accession #    P30711 [Other Products]
 Molecular Weight    13,517 Da
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 NCBI Official Full Name    glutathione S-transferase theta-1 isoform a
 NCBI Official Synonym Full Names    glutathione S-transferase theta 1
 NCBI Official Symbol    GSTT1 [Similar Products]
 NCBI Protein Information    glutathione S-transferase theta-1; GST class-theta-1; glutathione transferase T1-1
 UniProt Protein Name    Glutathione S-transferase theta-1
 UniProt Synonym Protein Names   
GST class-theta-1; Glutathione transferase T1-1
 Protein Family    Glutathione S-transferase
 UniProt Gene Name    GSTT1 [Similar Products]
 UniProt Entry Name    GSTT1_HUMAN
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 NCBI Summary for GSTt1    The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1 and GSTT2. GSTT1 and GSTT2 share 55% amino acid sequence identity and both may play an important role in human carcinogenesis. The GSTT1 and GSTT2 genes have a similar structure, being composed of five exons with identical exon/intron boundaries. This GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes, which are also located on chromosome 22, have been identified. [provided by RefSeq, Jun 2014]
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 UniProt Comments for GSTt1    GSTT1: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2- epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4- nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide. Belongs to the GST superfamily. Theta family.

Protein type: Xenobiotic Metabolism - metabolism by cytochrome P450; EC 2.5.1.18; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Other Amino Acids Metabolism - glutathione; Transferase

Chromosomal Location of Human Ortholog: 22q11.23

Cellular Component: cytosol

Molecular Function: glutathione transferase activity; glutathione peroxidase activity

Biological Process: glutathione metabolic process; xenobiotic metabolic process
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 Research Articles on GSTt1    1. GSTT1 deletion is related to polycyclic aromatic hydrocarbons-induced DNA damage and lymphoma progression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GSTt1 elisa kitPathways associated with GSTt1 elisa kit
 Reference Product  PubMed Publications
 GSTM1 elisa kit  >2036 publications with GSTt1 and GSTM1
 GSTP1 elisa kit  >904 publications with GSTt1 and GSTP1
 CYP1A1 elisa kit  >413 publications with GSTt1 and CYP1A1
 GSTA1 elisa kit  >94 publications with GSTt1 and GSTA1
 GSTA2 elisa kit  >6 publications with GSTt1 and GSTA2
 GSTA4 elisa kit  >6 publications with GSTt1 and GSTA4
 GSTA3 elisa kit  >4 publications with GSTt1 and GSTA3
 ATM elisa kit  >3 publications with GSTt1 and ATM
 Products by Pathway  Pathway Diagram
 Aflatoxin B1 Metabolism Pathway antibodies  Aflatoxin B1 Metabolism Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway antibodies  Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway Diagram
 Defective GCLC Causes Hemolytic Anemia Due To Gamma-glutamylcysteine Synthetase Deficiency (HAGGSD) Pathway antibodies  Defective GCLC Causes Hemolytic Anemia Due To Gamma-glutamylcysteine Synthetase Deficiency (HAGGSD) Pathway Diagram
 Defective GGT1 Causes Glutathionuria (GLUTH) Pathway antibodies  Defective GGT1 Causes Glutathionuria (GLUTH) Pathway Diagram
 Defective GSS Causes Glutathione Synthetase Deficiency (GSS Deficiency) Pathway antibodies  Defective GSS Causes Glutathione Synthetase Deficiency (GSS Deficiency) Pathway Diagram
 Defective MAT1A Causes Methionine Adenosyltransferase Deficiency (MATD) Pathway antibodies  Defective MAT1A Causes Methionine Adenosyltransferase Deficiency (MATD) Pathway Diagram
 Defective OPLAH Causes 5-oxoprolinase Deficiency (OPLAHD) Pathway antibodies  Defective OPLAH Causes 5-oxoprolinase Deficiency (OPLAHD) Pathway Diagram
Diseases associated with GSTt1 elisa kitOrgans/Tissues associated with GSTt1 elisa kit
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >348 publications with GSTt1 and Carcinoma
 Lung Diseases Antibodies  >234 publications with GSTt1 and Lung Diseases
 Lung Neoplasms Antibodies  >146 publications with GSTt1 and Lung Neoplasms
 Breast Neoplasms Antibodies  >109 publications with GSTt1 and Breast Neoplasms
 Chromosome Aberrations Antibodies  >108 publications with GSTt1 and Chromosome Aberrations
 Nervous System Diseases Antibodies  >107 publications with GSTt1 and Nervous System Diseases
 Liver Diseases Antibodies  >107 publications with GSTt1 and Liver Diseases
 Urinary Bladder Neoplasms Antibodies  >83 publications with GSTt1 and Urinary Bladder Neoplasms
 Poisoning Antibodies  >75 publications with GSTt1 and Poisoning
 Prostatic Neoplasms Antibodies  >61 publications with GSTt1 and Prostatic Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >663 publications with GSTt1 and Blood
 Lung Antibodies  >220 publications with GSTt1 and Lung
 Liver Antibodies  >177 publications with GSTt1 and Liver
 Bladder Antibodies  >105 publications with GSTt1 and Bladder
 Stomach Antibodies  >74 publications with GSTt1 and Stomach
 Prostate Antibodies  >71 publications with GSTt1 and Prostate
 Skin Antibodies  >64 publications with GSTt1 and Skin
 Kidney Antibodies  >63 publications with GSTt1 and Kidney
 Mouth Antibodies  >50 publications with GSTt1 and Mouth
 Brain Antibodies  >45 publications with GSTt1 and Brain
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