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GDF11 elisa kit :: Mouse Growth Differentiation Factor 11 (GDF11) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2021645 (SPECIAL PROMOTION: Get FREE Starbucks gift card ($5 for 48-Wells-Kit or $10 for 96-Wells-Kit. Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells  /  $270 +1 FREE 8GB USB
48-Strip-Wells  /  $505 +1 FREE 8GB USB
96-Strip-Wells  /  $685 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,770 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,025 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Growth Differentiation Factor 11 (GDF11), ELISA Kit

★Popular Item★
 Also Known As   

Growth Differentiation Factor 11 (GDF11) ELISA Kit

 Product Synonym Names    BMP11; Bone morphogenetic protein 11
 Product Gene Name   

GDF11 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    603936
 3D Structure    ModBase 3D Structure for O95390
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 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of GDF11. No significant cross-reactivity or interference between GDF11 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids
 Assay Type    Quantitative Sandwich
 Detection Range    12.5-800pg/mL
 Sensitivity    4.8pg/mL
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level GDF11 were tested 20 times on one plate, respectively. Intra-Assay: CV<10%
 Inter-assay Precision    Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level GDF11 were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100. Inter-Assay: CV<12%
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 Preparation and Storage    The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of GDF11 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GDF11 purchase    MBS2021645 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Growth Differentiation Factor 11 (GDF11) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 12.5-800pg/mL in biological research samples containing GDF11, with an estimated sensitivity of 4.8pg/mL. The ELISA analytical biochemical technique of the MBS2021645 kit is based on GDF11 antibody-GDF11 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GDF11 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GDF11. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for GDF11 elisa kit

   Intended Uses: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of GDF11 in mouse serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Principle of the Assay: The microplate provided in this kit has been pre-coated with an antibody specific to GDF11. Standards or samples are then added to the appropriate microplate wells with a biotin-conjugated antibody specific to GDF11. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain GDF11, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm 10nm. The concentration of GDF11 in the samples is then determined by comparing the O.D. of the samples to the standard curve.
 Product Categories/Family for GDF11 elisa kit    Cytokine; Neuroscience; Ophthalmology & Otorhinolaryngology; Developmental science; Bone metabolism
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 Typical Testing Data/Standard Curve (for reference only) of GDF11 elisa kit    GDF11 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2021645. Click to request current manual
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NCBI/Uniprot data below describe general gene information for GDF11. It may not necessarily be applicable to this product.
 NCBI GI #    119617237
 NCBI GeneID    10220
 NCBI Accession #    EAW96831.1 [Other Products]
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 UniProt Primary Accession #    O95390 [Other Products]
 UniProt Secondary Accession #    Q9UID1; Q9UID2 [Other Products]
 UniProt Related Accession #    O95390 [Other Products]
 Molecular Weight    45,091 Da
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 NCBI Official Full Name    growth differentiation factor 11, isoform CRA_a
 NCBI Official Synonym Full Names    growth differentiation factor 11
 NCBI Official Symbol    GDF11 [Similar Products]
 NCBI Official Synonym Symbols   
BMP11; BMP-11
[Similar Products]
 NCBI Protein Information    growth/differentiation factor 11
 UniProt Protein Name    Growth/differentiation factor 11
 UniProt Synonym Protein Names   
Bone morphogenetic protein 11; BMP-11
 Protein Family    Growth/differentiation factor
 UniProt Gene Name    GDF11 [Similar Products]
 UniProt Synonym Gene Names    BMP11; GDF-11; BMP-11 [Similar Products]
 UniProt Entry Name    GDF11_HUMAN
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 NCBI Summary for GDF11    The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development. [provided by RefSeq, Jul 2008]
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 UniProt Comments for GDF11    GDF11: Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 12q13.2

Cellular Component: extracellular space

Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: regulation of apoptosis; negative regulation of cell proliferation; nervous system development; negative regulation of cell differentiation; camera-type eye morphogenesis; spinal cord anterior/posterior patterning; ureteric bud development; regulation of MAPKKK cascade; cell maturation; pancreas development; mesoderm development; palate development; skeletal development; cell development; metanephros development; growth
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 Research Articles on GDF11    1. Suggest GDF11 functions as encephalic regionalizing factor in neural differentiated mouse embryonic stem cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GDF11 elisa kitDiseases associated with GDF11 elisa kit
 Reference Product  PubMed Publications
 WFIKKN2 elisa kit  >4 publications with GDF11 and WFIKKN2
 WFIKKN1 elisa kit  >3 publications with GDF11 and WFIKKN1
 ACVR2B elisa kit  >3 publications with GDF11 and ACVR2B
 WIF1 elisa kit  >1 publications with GDF11 and WIF1
 MAFA elisa kit  >1 publications with GDF11 and MAFA
 FOXG1 elisa kit  >1 publications with GDF11 and FOXG1
 CDKN1A elisa kit  >1 publications with GDF11 and CDKN1A
 ACVR1B elisa kit  >1 publications with GDF11 and ACVR1B
 ATOH7 elisa kit  >1 publications with GDF11 and ATOH7
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >7 publications with GDF11 and Congenital Abnormalities
 Disease Models, Animal Antibodies  >5 publications with GDF11 and Disease Models, Animal
 Kidney Diseases Antibodies  >3 publications with GDF11 and Kidney Diseases
 Fetal Death Antibodies  >1 publications with GDF11 and Fetal Death
 Inflammation Antibodies  >1 publications with GDF11 and Inflammation
 Fatty Liver Antibodies  >1 publications with GDF11 and Fatty Liver
 Necrosis Antibodies  >1 publications with GDF11 and Necrosis
 Neoplasms, Experimental Antibodies  >1 publications with GDF11 and Neoplasms, Experimental
 Urogenital Abnormalities Antibodies  >1 publications with GDF11 and Urogenital Abnormalities
 Neoplasm Metastasis Antibodies  >1 publications with GDF11 and Neoplasm Metastasis
Organs/Tissues associated with GDF11 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >77 publications with GDF11 and Bone
 Muscle Antibodies  >32 publications with GDF11 and Muscle
 Blood Antibodies  >17 publications with GDF11 and Blood
 Embryonic Tissue Antibodies  >16 publications with GDF11 and Embryonic Tissue
 Nerve Antibodies  >11 publications with GDF11 and Nerve
 Heart Antibodies  >10 publications with GDF11 and Heart
 Kidney Antibodies  >9 publications with GDF11 and Kidney
 Brain Antibodies  >9 publications with GDF11 and Brain
 Eye Antibodies  >6 publications with GDF11 and Eye
 Liver Antibodies  >5 publications with GDF11 and Liver
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