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HP elisa kit :: Mouse HP ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2505525
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HP, ELISA Kit

★Popular Item★
 Also Known As   

Mouse HP (Haptoglobin) ELISA Kit

 Product Gene Name   

HP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    140100
 3D Structure    ModBase 3D Structure for P00738
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 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Mouse HP. No significant cross-reactivity or interference between Mouse HP and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Mouse HP and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    78.125--5000ng/mL
 Sensitivity    46.875ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of HP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HP purchase    MBS2505525 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the HP, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 78.125--5000ng/mL in biological research samples containing HP, with an estimated sensitivity of 46.875ng/mL. The ELISA analytical biochemical technique of the MBS2505525 kit is based on HP antibody-HP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for HP elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of HP in Mouse serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse HP. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Mouse HP and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse HP, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Mouse HP. You can calculate the concentration of Mouse HP in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of HP elisa kit    HP elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2505525. Click to request current manual
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NCBI/Uniprot data below describe general gene information for HP. It may not necessarily be applicable to this product.
 NCBI GI #    186910296
 NCBI GeneID    3240
 NCBI Accession #    NP_001119574.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001126102.1 [Other Products]
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 UniProt Primary Accession #    P00738 [Other Products]
 UniProt Secondary Accession #    P00737; Q0VAC4; Q0VAC5; Q2PP15; Q3B7J0; Q6LBY9; Q9UC67; B0AZL5 [Other Products]
 UniProt Related Accession #    P00738 [Other Products]
 Molecular Weight    38,452 Da
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 NCBI Official Full Name    haptoglobin isoform 2 preproprotein
 NCBI Official Synonym Full Names    haptoglobin
 NCBI Official Symbol    HP [Similar Products]
 NCBI Official Synonym Symbols   
BP; HPA1S; HP2ALPHA2
[Similar Products]
 NCBI Protein Information    haptoglobin; binding peptide; haptoglobin alpha(1S)-beta; haptoglobin alpha(2FS)-beta; haptoglobin, alpha polypeptide; haptoglobin, beta polypeptide; zonulin
 UniProt Protein Name    Haptoglobin
 UniProt Synonym Protein Names   
ZonulinCleaved into the following 2 chains:Haptoglobin alpha chain; Haptoglobin beta chain
 Protein Family    HPr-like protein
 UniProt Gene Name    HP [Similar Products]
 UniProt Entry Name    HPT_HUMAN
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 NCBI Summary for HP    This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. The protein encoded also exhibits antimicrobial activity against bacteria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
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 UniProt Comments for HP    HP: Haptoglobin combines with free plasma hemoglobin, preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin, while making the hemoglobin accessible to degradative enzymes. Defects in HP are the cause of anhaptoglobinemia (AHP). AHP is a condition characterized by the absence of the serum glycoprotein haptoglobin. Serum levels of haptoglobin vary among normal persons: levels are low in the neonatal period and in the elderly, differ by population, and can be influenced by environmental factors, such as infection. Secondary hypohaptoglobinemia can occur as a consequence of hemolysis, during which haptoglobin binds to free hemoglobin. Belongs to the peptidase S1 family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 16q22.2

Cellular Component: extracellular space; extracellular region

Molecular Function: antioxidant activity; protein binding; hemoglobin binding; catalytic activity

Biological Process: receptor-mediated endocytosis; response to hydrogen peroxide; metabolic process; immune system process; defense response to bacterium; negative regulation of oxidoreductase activity; acute-phase response; defense response

Disease: Anhaptoglobinemia
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 Research Articles on HP    1. Serum zonulin is increased in polycystic ovary syndrome and correlates with insulin resistance and severity of anovulation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HP elisa kitPathways associated with HP elisa kit
 Reference Product  PubMed Publications
 CD163 elisa kit  >60 publications with HP and CD163
 APOE elisa kit  >30 publications with HP and APOE
 IL6 elisa kit  >28 publications with HP and IL6
 HBA1 elisa kit  >25 publications with HP and HBA1
 APOA1 elisa kit  >13 publications with HP and APOA1
 HBB elisa kit  >4 publications with HP and HBB
 MIS12 elisa kit  >2 publications with HP and MIS12
 Products by Pathway  Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Scavenging Of Heme From Plasma Pathway antibodies  Scavenging Of Heme From Plasma Pathway Diagram
 Amb2 Integrin Signaling Pathway antibodies  Amb2 Integrin Signaling Pathway Diagram
Diseases associated with HP elisa kitOrgans/Tissues associated with HP elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >1596 publications with HP and Cardiovascular Diseases
 Inflammation Antibodies  >1109 publications with HP and Inflammation
 Hypersensitivity Antibodies  >645 publications with HP and Hypersensitivity
 Liver Diseases Antibodies  >592 publications with HP and Liver Diseases
 Disease Models, Animal Antibodies  >524 publications with HP and Disease Models, Animal
 Hypertension Antibodies  >476 publications with HP and Hypertension
 Kidney Diseases Antibodies  >464 publications with HP and Kidney Diseases
 Autoimmune Diseases Antibodies  >460 publications with HP and Autoimmune Diseases
 Necrosis Antibodies  >454 publications with HP and Necrosis
 Fibrosis Antibodies  >437 publications with HP and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5478 publications with HP and Blood
 Brain Antibodies  >1260 publications with HP and Brain
 Liver Antibodies  >1208 publications with HP and Liver
 Lung Antibodies  >1127 publications with HP and Lung
 Muscle Antibodies  >723 publications with HP and Muscle
 Kidney Antibodies  >677 publications with HP and Kidney
 Connective Tissue Antibodies  >324 publications with HP and Connective Tissue
 Bone Marrow Antibodies  >220 publications with HP and Bone Marrow
 Adipose Tissue Antibodies  >174 publications with HP and Adipose Tissue
 Ovary Antibodies  >146 publications with HP and Ovary
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