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HSP72 elisa kit :: Mouse Heat Shock Protein 72 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS724028 HSP72 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Heat Shock Protein 72 (HSP72), ELISA Kit

 Also Known As   

Mouse Heat Shock Protein 72 ELISA Kit

 Product Gene Name   

HSP72 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    gene 603012
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 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of HSP72 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HSP72 purchase    MBS724028 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Heat Shock Protein 72 (HSP72) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HSP72. The ELISA analytical biochemical technique of the MBS724028 kit is based on HSP72 antibody-HSP72 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HSP72 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HSP72. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for HSP72 elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for HSP72. It may not necessarily be applicable to this product.
 NCBI GI #    194248072
 NCBI GeneID    3303
 NCBI Accession #    NP_005336.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_005345.5 [Other Products]
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 UniProt Secondary Accession #    P19790; Q5JQI4; Q5SP17; Q9UQL9; Q9UQM0; B4E3B6 [Other Products]
 UniProt Related Accession #    P08107 [Other Products]
 Molecular Weight    63,937 Da
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 NCBI Official Full Name    heat shock 70 kDa protein 1A/1B
 NCBI Official Synonym Full Names    heat shock 70kDa protein 1A
 NCBI Official Symbol    HSPA1A [Similar Products]
 NCBI Official Synonym Symbols   
HSP72; HSPA1; HSP70I; HSP70-1; HSP70-1A; HEL-S-103
[Similar Products]
 NCBI Protein Information    heat shock 70 kDa protein 1A/1B; HSP70-1/HSP70-2; heat shock 70kD protein 1A; heat shock-induced protein; heat shock 70 kDa protein 1/2; epididymis secretory protein Li 103; dnaK-type molecular chaperone HSP70-1
 UniProt Protein Name    Heat shock 70 kDa protein 1A/1B
 UniProt Synonym Protein Names   
Heat shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2
 UniProt Gene Name    HSPA1A [Similar Products]
 UniProt Synonym Gene Names    HSPA1; HSX70
HSPA1B; HSP70-1/HSP70-2; HSP70.1/HSP70.2
[Similar Products]
 UniProt Entry Name    HSP71_HUMAN
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 NCBI Summary for HSP72    This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]
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 UniProt Comments for HSP72    HSP70: a critical chaperone protein that has a high affinity for unfolded polypeptide chains. It binds extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In cooperation with other chaperones, hsp70 stabilizes preexistent proteins against aggregation and mediates the folding of newly translated polypeptides in the cytosol as well as within organelles. Mitochondrial HSP70 is crucial to the import process: mutant forms of HSP70 fail to import precursor proteins. Is anti-apoptotic in sympathetic neurones and mediates this effect primarily by suppressing c-Jun transcriptional signalling. Interacts with tau protein and mediates proper folding of tau. Can promote the degradation of tau protein. Triptolide, a potential therapeutic agent for progression/metastasis of pancreatic cancer, causes pancreatic cancer cell death by induction of apoptosis, an effect mediated by the inhibition of HSP70.

Protein type: Chaperone; Motility/polarity/chemotaxis; Heat shock protein

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: signalosome; focal adhesion; mitochondrion; endoplasmic reticulum; inclusion body; cytosol; ribonucleoprotein complex; nucleoplasm; centriole; perinuclear region of cytoplasm; cytoplasm; nuclear speck; nucleus; ubiquitin ligase complex; vesicle

Molecular Function: viral receptor activity; protein binding; enzyme binding; G-protein-coupled receptor binding; ubiquitin protein ligase binding; heat shock protein binding; ATPase activity; unfolded protein binding; double-stranded RNA binding; protein N-terminus binding; ATPase activity, coupled; ATP binding

Biological Process: negative regulation of cell proliferation; entry of virus into host cell; protein stabilization; positive regulation of erythrocyte differentiation; mRNA catabolic process; negative regulation of protein ubiquitination; gene expression; protein refolding; negative regulation of cell growth; response to unfolded protein; negative regulation of apoptosis
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 Research Articles on HSP72    1. Study reveals that Hsp70, known to facilitate client delivery to Hsp90, inactivates GR through partial unfolding, whereas Hsp90 reverses this inactivation. Full recovery of ligand binding requires ATP hydrolysis on Hsp90 and the Hop and p23 cochaperones.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HSP72 elisa kitPathways associated with HSP72 elisa kit
 Reference Product  PubMed Publications
 DNAJB1 elisa kit  >19 publications with HSP72 and DNAJB1
 HSF1 elisa kit  >14 publications with HSP72 and HSF1
 BAG3 elisa kit  >6 publications with HSP72 and BAG3
 STIP1 elisa kit  >3 publications with HSP72 and STIP1
 HSPBP1 elisa kit  >3 publications with HSP72 and HSPBP1
 BAG1 elisa kit  >3 publications with HSP72 and BAG1
 TP53 elisa kit  >2 publications with HSP72 and TP53
 STUB1 elisa kit  >1 publications with HSP72 and STUB1
 Products by Pathway  Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Apoptosis Modulation By HSP70 Pathway antibodies  Apoptosis Modulation By HSP70 Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
Diseases associated with HSP72 elisa kitOrgans/Tissues associated with HSP72 elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >26 publications with HSP72 and Cardiovascular Diseases
 Inflammation Antibodies  >22 publications with HSP72 and Inflammation
 Nervous System Diseases Antibodies  >14 publications with HSP72 and Nervous System Diseases
 Heart Diseases Antibodies  >11 publications with HSP72 and Heart Diseases
 Necrosis Antibodies  >10 publications with HSP72 and Necrosis
 Atherosclerosis Antibodies  >9 publications with HSP72 and Atherosclerosis
 Brain Diseases Antibodies  >9 publications with HSP72 and Brain Diseases
 Liver Diseases Antibodies  >9 publications with HSP72 and Liver Diseases
 Liver Neoplasms Antibodies  >6 publications with HSP72 and Liver Neoplasms
 Myocardial Ischemia Antibodies  >5 publications with HSP72 and Myocardial Ischemia
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >20 publications with HSP72 and Brain
 Liver Antibodies  >18 publications with HSP72 and Liver
 Kidney Antibodies  >11 publications with HSP72 and Kidney
 Vascular Antibodies  >11 publications with HSP72 and Vascular
 Heart Antibodies  >9 publications with HSP72 and Heart
 Nerve Antibodies  >9 publications with HSP72 and Nerve
 Muscle Antibodies  >9 publications with HSP72 and Muscle
 Skin Antibodies  >8 publications with HSP72 and Skin
 Lung Antibodies  >7 publications with HSP72 and Lung
 Intestine Antibodies  >4 publications with HSP72 and Intestine
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