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IL18BP elisa kit :: Mouse IL18BP ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2507231
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
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 Product Name   


★Popular Item★
 Also Known As   

Mouse IL18BP (Interleukin 18 Binding Protein) ELISA Kit

 Product Gene Name   

IL18BP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2507231 COA    COA PDF
 OMIM    604113
 3D Structure    ModBase 3D Structure for O95998
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 Species Reactivity    Mouse
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 Specificity    This kit recognizes natural and recombinant Mouse IL18BP. No significant cross-reactivity or interference between Mouse IL18BP and analogues was observed.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.156-10ng/mL
 Sensitivity    Min: 0.094ng/mL; Max: 10ng/mL
 Intended Uses    This ELISA kit applies to the in vitro quantitative determination of Mouse IL18BP concentrations in serum, plasma and other biological fluids.
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IL18BP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL18BP purchase    MBS2507231 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the IL18BP, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156-10ng/mL in biological research samples containing IL18BP, with an estimated sensitivity of Min: 0.094ng/mL; Max: 10ng/mL. The ELISA analytical biochemical technique of the MBS2507231 kit is based on IL18BP antibody-IL18BP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL18BP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL18BP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for IL18BP elisa kit

   Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to IL18BP. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for IL18BP and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain IL18BP, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of IL18BP. You can calculate the concentration of IL18BP in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of IL18BP elisa kit    IL18BP elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2507231. Click to request current manual
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NCBI/Uniprot data below describe general gene information for IL18BP. It may not necessarily be applicable to this product.
 NCBI GI #    323098348
 NCBI GeneID    10068
 NCBI Accession #    NP_005690.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_005699.3 [Other Products]
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 UniProt Primary Accession #    O95998 [Other Products]
 UniProt Secondary Accession #    O95993; O96027; Q9NZA9; Q9UBR7; B3KUZ0; B7WPK4 [Other Products]
 UniProt Related Accession #    O95998 [Other Products]
 Molecular Weight    17,478 Da
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 NCBI Official Full Name    interleukin-18-binding protein isoform c
 NCBI Official Synonym Full Names    interleukin 18 binding protein
 NCBI Official Symbol    IL18BP [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    interleukin-18-binding protein; IL-18BP; MC51L-53L-54L homolog gene product; tadekinig-alfa
 UniProt Protein Name    Interleukin-18-binding protein
 UniProt Synonym Protein Names   
 Protein Family    Interleukin-18-binding protein
 UniProt Gene Name    IL18BP [Similar Products]
 UniProt Synonym Gene Names    IL-18BP [Similar Products]
 UniProt Entry Name    I18BP_HUMAN
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 NCBI Summary for IL18BP    The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
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 UniProt Comments for IL18BP    IL18BP: Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: extracellular space; extracellular region

Molecular Function: receptor antagonist activity; interleukin-18 binding

Biological Process: T-helper 1 type immune response; response to lipopolysaccharide
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 Research Articles on IL18BP    1. HPV16 E7 oncoprotein increases production of the IL18BP in keratinocytes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL18BP elisa kitDiseases associated with IL18BP elisa kit
 Reference Product  PubMed Publications
 IL18 elisa kit  >19 publications with IL18BP and IL18
 IL18RAP elisa kit  >2 publications with IL18BP and IL18RAP
 CASP1 elisa kit  >2 publications with IL18BP and CASP1
 CXCL10 elisa kit  >2 publications with IL18BP and CXCL10
 IFNG elisa kit  >1 publications with IL18BP and IFNG
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >5 publications with IL18BP and Heart Diseases
 Inflammation Antibodies  >3 publications with IL18BP and Inflammation
 Hypertrophy Antibodies  >2 publications with IL18BP and Hypertrophy
 Necrosis Antibodies  >2 publications with IL18BP and Necrosis
 Neoplasms, Experimental Antibodies  >2 publications with IL18BP and Neoplasms, Experimental
 Cardiomegaly Antibodies  >2 publications with IL18BP and Cardiomegaly
 Infertility, Female Antibodies  >1 publications with IL18BP and Infertility, Female
 Blood Coagulation Disorders Antibodies  >1 publications with IL18BP and Blood Coagulation Disorders
 Arteriosclerosis Antibodies  >1 publications with IL18BP and Arteriosclerosis
 Liver Diseases Antibodies  >1 publications with IL18BP and Liver Diseases
Organs/Tissues associated with IL18BP elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >10 publications with IL18BP and Blood
 Heart Antibodies  >4 publications with IL18BP and Heart
 Muscle Antibodies  >3 publications with IL18BP and Muscle
 Liver Antibodies  >2 publications with IL18BP and Liver
 Ovary Antibodies  >2 publications with IL18BP and Ovary
 Skin Antibodies  >1 publications with IL18BP and Skin
 Thymus Antibodies  >1 publications with IL18BP and Thymus
 Uterus Antibodies  >1 publications with IL18BP and Uterus
 Spleen Antibodies  >1 publications with IL18BP and Spleen
 Lung Antibodies  >1 publications with IL18BP and Lung
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