NP_080850.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
175,533 Da
NCBI Official Full Name
DNA helicase INO80
NCBI Official Synonym Full Names
INO80 homolog (S. cerevisiae)
NCBI Official Synonym Symbols
Inoc1; 2310079N15Rik; 4632409L19Rik [Similar Products]
NCBI Protein Information
DNA helicase INO80; INO80 complex homolog 1; INO80 complex subunit A; yeast INO80-like protein; putative DNA helicase INO80 complex homolog 1
UniProt Protein Name
DNA helicase INO80
UniProt Synonym Protein Names
INO80 complex subunit A; Putative DNA helicase INO80 complex homolog 1
UniProt Synonym Gene Names
UniProt Entry Name
INO80_MOUSE
UniProt Comments for INO80
INOC1: DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle. Belongs to the SNF2/RAD54 helicase family.
Protein type: Helicase; DNA-binding; EC 3.6.4.12
Cellular Component: microtubule; nucleus
Molecular Function: DNA helicase activity; hydrolase activity, acting on acid anhydrides; DNA binding; hydrolase activity; ATPase activity; nucleotide binding; actin binding; helicase activity; ATP binding; alpha-tubulin binding
Biological Process: mitosis; mitotic sister chromatid segregation; spindle assembly; cell cycle; DNA repair; positive regulation of cell growth; double-strand break repair via homologous recombination; DNA duplex unwinding; DNA recombination; chromatin remodeling; cell division; double-strand break repair; positive regulation of transcription from RNA polymerase II promoter; response to DNA damage stimulus
Research Articles on INO80
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Diseases associated with INO80 elisa kit
Organs/Tissues associated with INO80 elisa kit
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