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IL10Ra elisa kit :: Mouse Interleukin 10 Receptor Alpha (IL10Ra) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9309860 IL10Ra elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 10 Receptor Alpha (IL10Ra), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Interleukin 10 Receptor Alpha (IL10Ra) ELISA Kit

 Product Gene Name   

IL10Ra elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 11; NC_000011.10 (117986386..118001483). Location: 11q23
 OMIM    146933
 3D Structure    ModBase 3D Structure for Q13651
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 Species Reactivity    Mouse
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances
 Assay Type    Sandwich
 Detection Range    15.6 pg/ml - 500 pg/ml
 Sensitivity    2.0 pg/ml
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IL10Ra elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL10Ra purchase    MBS9309860 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin 10 Receptor Alpha (IL10Ra) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.6 pg/ml - 500 pg/ml in biological research samples containing IL10Ra, with an estimated sensitivity of 2.0 pg/ml. The ELISA analytical biochemical technique of the MBS9309860 kit is based on IL10Ra antibody-IL10Ra antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL10Ra antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL10Ra. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for IL10Ra elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of IL10RA (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9309860. Click to request current manual
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NCBI/Uniprot data below describe general gene information for IL10Ra. It may not necessarily be applicable to this product.
 NCBI GI #    222136575
 NCBI GeneID    3587
 NCBI Accession #    NP_001549.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001558.3 [Other Products]
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 UniProt Primary Accession #    Q13651 [Other Products]
 UniProt Secondary Accession #    A8K6I0; B0YJ27 [Other Products]
 UniProt Related Accession #    Q13651 [Other Products]
 Molecular Weight    63,003 Da
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 NCBI Official Full Name    interleukin-10 receptor subunit alpha
 NCBI Official Synonym Full Names    interleukin 10 receptor, alpha
 NCBI Official Symbol    IL10RA [Similar Products]
 NCBI Official Synonym Symbols   
CD210; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1
[Similar Products]
 NCBI Protein Information    interleukin-10 receptor subunit alpha; IL-10RA; IL-10R subunit 1; IL-10R subunit alpha; IL-10 receptor subunit alpha; interleukin-10 receptor subunit 1; interleukin-10 receptor alpha chain
 UniProt Protein Name    Interleukin-10 receptor subunit alpha
 UniProt Synonym Protein Names   
CDw210a; Interleukin-10 receptor subunit 1
 Protein Family    Interleukin-10 receptor
 UniProt Gene Name    IL10RA [Similar Products]
 UniProt Synonym Gene Names    IL10R; IL-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; IL-10R subunit 1; IL-10R1 [Similar Products]
 UniProt Entry Name    I10R1_HUMAN
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 NCBI Summary for IL10Ra    The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009]
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 UniProt Comments for IL10Ra    IL10RA: a receptor for interleukin 10 structurally related to interferon receptors. Mediates the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.

Protein type: Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 11q23

Cellular Component: integral to membrane; plasma membrane

Molecular Function: signal transducer activity; interleukin-10 binding; protein binding; interleukin-10 receptor activity; receptor activity

Biological Process: cytokine and chemokine mediated signaling pathway; response to lipopolysaccharide

Disease: Inflammatory Bowel Disease 28, Autosomal Recessive
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 Research Articles on IL10Ra    1. 5 patients with an IL-10R1 or IL-10R2 deficiency developed B-cell non-Hodgkin lymphoma between the ages of 5 and 6 years (which was recurrent in 1 patient).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL10Ra elisa kitPathways associated with IL10Ra elisa kit
 Reference Product  PubMed Publications
 IL10 elisa kit  >28 publications with IL10Ra and IL10
 IL10RB elisa kit  >14 publications with IL10Ra and IL10RB
 JAK1 elisa kit  >1 publications with IL10Ra and JAK1
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Toxoplasmosis Pathway antibodies  Toxoplasmosis Pathway Diagram
 Toxoplasmosis Pathway antibodies  Toxoplasmosis Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
Diseases associated with IL10Ra elisa kitOrgans/Tissues associated with IL10Ra elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >13 publications with IL10Ra and Inflammation
 Necrosis Antibodies  >6 publications with IL10Ra and Necrosis
 Cardiovascular Diseases Antibodies  >4 publications with IL10Ra and Cardiovascular Diseases
 Neoplasms Antibodies  >4 publications with IL10Ra and Neoplasms
 Brain Diseases Antibodies  >2 publications with IL10Ra and Brain Diseases
 Liver Diseases Antibodies  >2 publications with IL10Ra and Liver Diseases
 Skin Diseases Antibodies  >2 publications with IL10Ra and Skin Diseases
 Disease Models, Animal Antibodies  >1 publications with IL10Ra and Disease Models, Animal
 Lung Diseases Antibodies  >1 publications with IL10Ra and Lung Diseases
 Kidney Diseases Antibodies  >1 publications with IL10Ra and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >17 publications with IL10Ra and Blood
 Skin Antibodies  >5 publications with IL10Ra and Skin
 Bone Antibodies  >4 publications with IL10Ra and Bone
 Brain Antibodies  >3 publications with IL10Ra and Brain
 Vascular Antibodies  >2 publications with IL10Ra and Vascular
 Intestine Antibodies  >2 publications with IL10Ra and Intestine
 Tonsil Antibodies  >1 publications with IL10Ra and Tonsil
 Pancreas Antibodies  >1 publications with IL10Ra and Pancreas
 Pharynx Antibodies  >1 publications with IL10Ra and Pharynx
 Lung Antibodies  >1 publications with IL10Ra and Lung
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