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IL-12P35 elisa kit :: Mouse Interleukin 12 P35 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS011585 IL-12P35 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 12 P35 (IL-12P35), ELISA Kit

 Also Known As   

Mouse Interleukin 12 P35 ELISA Kit

 Product Gene Name   

IL-12P35 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    161560
 3D Structure    ModBase 3D Structure for P29459
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 Species Reactivity    Mouse
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IL-12P35 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL-12P35 purchase    MBS011585 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin 12 P35 (IL-12P35) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IL-12P35. The ELISA analytical biochemical technique of the MBS011585 kit is based on IL-12P35 antibody-IL-12P35 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL-12P35 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL-12P35. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for IL-12P35. It may not necessarily be applicable to this product.
 NCBI GI #    24430219
 NCBI GeneID    3592
 NCBI Accession #    NP_000873.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000882.3 [Other Products]
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 UniProt Primary Accession #    P29459 [Other Products]
 UniProt Secondary Accession #    Q96QZ1 [Other Products]
 UniProt Related Accession #    P29459 [Other Products]
 Molecular Weight    24,874 Da
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 NCBI Official Full Name    interleukin-12 subunit alpha
 NCBI Official Synonym Full Names    interleukin 12A
 NCBI Official Symbol    IL12A [Similar Products]
 NCBI Official Synonym Symbols   
P35; CLMF; NFSK; NKSF1; IL-12A
[Similar Products]
 NCBI Protein Information    interleukin-12 subunit alpha; CLMF p35; IL35 subunit; IL-12, subunit p35; interleukin 12, p35; interleukin-12 alpha chain; NF cell stimulatory factor chain 1; NK cell stimulatory factor chain 1; cytotoxic lymphocyte maturation factor 1, p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
 UniProt Protein Name    Interleukin-12 subunit alpha
 UniProt Synonym Protein Names   
Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; NK cell stimulatory factor chain 1
 UniProt Gene Name    IL12A [Similar Products]
 UniProt Synonym Gene Names    NKSF1; IL-12A; CLMF p35; NKSF1 [Similar Products]
 UniProt Entry Name    IL12A_HUMAN
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 NCBI Summary for IL-12P35    This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IL-12P35    IL12A: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-6 superfamily.

Protein type: Secreted, signal peptide; Secreted; Cytokine

Chromosomal Location of Human Ortholog: 3q25.33

Cellular Component: extracellular space; interleukin-12 complex; cytoplasm

Molecular Function: interleukin-27 binding; protein binding; interleukin-12 beta subunit binding; growth factor activity; protein heterodimerization activity; cytokine activity; interleukin-12 receptor binding

Biological Process: cell migration; positive regulation of NK T cell activation; positive regulation of cell adhesion; positive regulation of T cell mediated cytotoxicity; negative regulation of smooth muscle cell proliferation; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; response to virus; positive regulation of tyrosine phosphorylation of Stat4 protein; response to lipopolysaccharide; defense response to protozoan; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of natural killer cell activation; response to UV-B; positive regulation of interferon-gamma production; defense response to Gram-positive bacterium; negative regulation of interleukin-17 production; positive regulation of T cell differentiation; positive regulation of mononuclear cell proliferation; positive regulation of lymphocyte proliferation; positive regulation of T cell proliferation; immune response; cell cycle arrest
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 Research Articles on IL-12P35    1. circulating IL-35 in PDAC patients significantly increased, suggesting that regulating the expression of IL-35 may provide a new possible target for the treatment of PDAC patients, especially for the resectable ones.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL-12P35 elisa kitPathways associated with IL-12P35 elisa kit
 Reference Product  PubMed Publications
 IL12B elisa kit  >47 publications with IL-12P35 and IL12B
 IL4 elisa kit  >18 publications with IL-12P35 and IL4
 IFNG elisa kit  >15 publications with IL-12P35 and IFNG
 IL12RB2 elisa kit  >12 publications with IL-12P35 and IL12RB2
 IL1B elisa kit  >11 publications with IL-12P35 and IL1B
 IL12RB1 elisa kit  >10 publications with IL-12P35 and IL12RB1
 STAT1 elisa kit  >5 publications with IL-12P35 and STAT1
 JAK2 elisa kit  >1 publications with IL-12P35 and JAK2
 Products by Pathway  Pathway Diagram
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 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
Diseases associated with IL-12P35 elisa kitOrgans/Tissues associated with IL-12P35 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >35 publications with IL-12P35 and Neoplasms
 Inflammation Antibodies  >18 publications with IL-12P35 and Inflammation
 Necrosis Antibodies  >16 publications with IL-12P35 and Necrosis
 Liver Diseases Antibodies  >11 publications with IL-12P35 and Liver Diseases
 Disease Models, Animal Antibodies  >10 publications with IL-12P35 and Disease Models, Animal
 Multiple Sclerosis Antibodies  >10 publications with IL-12P35 and Multiple Sclerosis
 Hepatitis Antibodies  >7 publications with IL-12P35 and Hepatitis
 Brain Diseases Antibodies  >7 publications with IL-12P35 and Brain Diseases
 Liver Cirrhosis, Biliary Antibodies  >7 publications with IL-12P35 and Liver Cirrhosis, Biliary
 Neoplasms, Experimental Antibodies  >5 publications with IL-12P35 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Spleen Antibodies  >5 publications with IL-12P35 and Spleen
 Uterus Antibodies  >3 publications with IL-12P35 and Uterus
 Brain Antibodies  >3 publications with IL-12P35 and Brain
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