AAI46188.1
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
26,294 Da
NCBI Official Full Name
IL34 protein
NCBI Official Synonym Full Names
interleukin 34<
NCBI Protein Information
interleukin-34
UniProt Protein Name
Interleukin-34
UniProt Synonym Gene Names
UniProt Entry Name
IL34_BOVIN
UniProt Comments for IL34
Function: Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1
By similarity.
Subunit structure: Homodimer. Interacts with CSF1R
By similarity.
Subcellular location: Secreted
By similarity UniProtKB Q6ZMJ4.
Sequence similarities: Belongs to the IL-34 family.
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Products associated with IL34 elisa kit
Organs/Tissues associated with IL34 elisa kit
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