View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List JAG1 elisa kit :: Mouse Jagged 1 Protein (JAG1) ELISA Kit Catalog # MBS2019463 (SPECIAL PROMOTION: Get FREE Starbucks gift card ($5 for 48-Wells-Kit or $10 for 96-Wells-Kit. Maximum 5 gift cards/product). Gift card(s) will be included with shipment) Unit / Price 24-Strip-Wells / $365 +1 FREE 8GB USB 48-Strip-Wells / $545 +1 FREE 8GB USB 96-Strip-Wells / $715 +1 FREE 8GB USB 5x96-Strip-Wells / $2,910 +3 FREE 8GB USB 10x96-Strip-Wells / $5,315 +6 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Jagged 1 Protein (JAG1), ELISA Kit Full Product Name Mouse Jagged 1 Protein (JAG1) ELISA Kit Product Synonym Names CD339; AGS; AHD; AWS; HJ1; JAGL1; Alagille Syndrome Product Gene Name JAG1 elisa kit[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sample Manual Insert Download Sample PDF Manual View Sample PDF Manual Species Reactivity Mouse Specificity This assay has high sensitivity and excellent specificity for detection of Jagged 1 Protein (JAG1). No significant cross-reactivity or interference between Jagged 1 Protein (JAG1) and analogues was observed. Assay Type Double-antibody Sandwich Samples Serum, Plasma, Tissue homogenates, Cell lysates, Cell culture supernates and other biological fluids Detection Range 0.156-10ng/mL Sensitivity 0.063ng/mL Application Enzyme-linked immunosorbent assay for Antigen Detection. Intra-assay Precision (Precision within an assay) 3 samples with low, middle and high level Jagged 1 Protein (JAG1) were tested 20 times on one plate, respectively. Inter-assay Precision (Precision between assays) 3 samples with low, middle and high level Jagged 1 Protein (JAG1) were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100 Intra-Assay CV<10% Inter-Assay CV<12% Preparation and Storage The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end. ISO Certification Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory. Supply Chain Verification Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire. Product Note Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details. Other Notes Small volumes of JAG1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. Searchable Terms for JAG1 purchase MBS2019463 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Jagged 1 Protein (JAG1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing JAG1. The ELISA analytical biochemical technique of the MBS2019463 kit is based on JAG1 antibody-JAG1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect JAG1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, JAG1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%). TOP Related Product Information for JAG1 elisa kit The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Jagged 1 Protein (JAG1). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Jagged 1 Protein (JAG1). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Jagged 1 Protein (JAG1), biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Jagged 1 Protein (JAG1) in the samples is then determined by comparing the O.D. of the samples to the standard curve. Product Categories/Family for JAG1 elisa kit Signal transduction; CD & Adhesion molecule; Tumor immunity; Hematology Typical Testing Data/Standard Curve (for reference only) of JAG1 elisa kit TOP Sample Manual Insert of MBS2019463. NCBI/Uniprot data below describe general gene information for JAG1. It may not necessarily be applicable to this product. NCBI GI # 215536139 NCBI GeneID 182 NCBI Accession # ACJ68517.1 [Other Products] UniProt Related Accession # P78504[Other Products] Molecular Weight 4,286 Da TOP NCBI Official Full Name jagged 1, partial NCBI Official Synonym Full Names jagged 1 NCBI Official Symbol JAG1 [Similar Products] NCBI Official Synonym Symbols AGS; AHD; AWS; HJ1; CD339; JAGL1 [Similar Products] NCBI Protein Information protein jagged-1 UniProt Protein Name Jagged 1 UniProt Synonym Protein Names Jagged 1 Protein Family Protein jagged UniProt Gene Name JAG1 [Similar Products] UniProt Entry Name B7U6M9_HUMAN TOP NCBI Summary for JAG1 The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008] TOP UniProt Comments for JAG1 JAG1: Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Interacts with NOTCH2 and NOTCH3. Interacts with NOTCH1 (in the presence of calcium ions). Widely expressed in adult and fetal tissues. In cervix epithelium expressed in undifferentiated subcolumnar reserve cells and squamous metaplasia. Expression is up-regulated in cervical squamous cell carcinoma. Expressed in bone marrow cell line HS-27a which supports the long-term maintenance of immature progenitor cells.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 20p12.1-p11.23Cellular Component: membrane; apical part of cell; integral to plasma membrane; extracellular region; plasma membraneMolecular Function: protein binding; growth factor activity; calcium ion binding; Notch binding; structural molecule activityBiological Process: nervous system development; endothelial cell differentiation; Notch signaling pathway; positive regulation of myeloid cell differentiation; T cell mediated immunity; Notch receptor processing; auditory receptor cell differentiation; cell fate determination; negative regulation of fat cell differentiation; regulation of cell migration; regulation of cell proliferation; myoblast differentiation; keratinocyte differentiation; positive regulation of osteoblast differentiation; negative regulation of neuron differentiation; response to muramyl dipeptide; morphogenesis of an epithelial sheet; blood vessel remodeling; hemopoiesis; positive regulation of transcription from RNA polymerase II promoter; angiogenesis; positive regulation of Notch signaling pathwayDisease: Tetralogy Of Fallot; Alagille Syndrome 1 Research Articles on JAG1 1. silencing prevents Notch2-driven osteoclast development and bone destruction in multiple myeloma TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with JAG1 elisa kit Reference Product PubMed Publications NOTCH1 elisa kit >104 publications with JAG1 and NOTCH1 DLL1 elisa kit >42 publications with JAG1 and DLL1 NOTCH3 elisa kit >36 publications with JAG1 and NOTCH3 NOTCH4 elisa kit >15 publications with JAG1 and NOTCH4 ADAM10 elisa kit >2 publications with JAG1 and ADAM10 MIB1 elisa kit >2 publications with JAG1 and MIB1 UBC elisa kit >1 publications with JAG1 and UBC Pathways associated with JAG1 elisa kit Products by Pathway Pathway Diagram Activated NOTCH1 Transmits Signal To The Nucleus Pathway antibodies Activated NOTCH1 Transmits Signal To The Nucleus Pathway Diagram Constitutive Signaling By NOTCH1 HD Domain Mutants Pathway antibodies Constitutive Signaling By NOTCH1 HD Domain Mutants Pathway Diagram Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway antibodies Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway Diagram Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway antibodies Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway Diagram Constitutive Signaling By NOTCH1 T(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Pathway antibodies Constitutive Signaling By NOTCH1 T(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Pathway Diagram Delta-Notch Signaling Pathway antibodies Delta-Notch Signaling Pathway Diagram Disease Pathway antibodies Disease Pathway Diagram Diseases Of Signal Transduction Pathway antibodies Diseases Of Signal Transduction Pathway Diagram NOTCH2 Activation And Transmission Of Signal To The Nucleus Pathway antibodies NOTCH2 Activation And Transmission Of Signal To The Nucleus Pathway Diagram Notch Signaling Pathway antibodies Notch Signaling Pathway Diagram Diseases associated with JAG1 elisa kit Disease Name Pubmed Publications Alagille Syndrome Antibodies >133 publications with JAG1 and Alagille Syndrome Liver Diseases Antibodies >117 publications with JAG1 and Liver Diseases Heart Defects, Congenital Antibodies >111 publications with JAG1 and Heart Defects, Congenital Facies Antibodies >34 publications with JAG1 and Facies Heart Diseases Antibodies >31 publications with JAG1 and Heart Diseases Breast Neoplasms Antibodies >24 publications with JAG1 and Breast Neoplasms Bone Diseases Antibodies >19 publications with JAG1 and Bone Diseases Chromosome Aberrations Antibodies >19 publications with JAG1 and Chromosome Aberrations Brain Diseases Antibodies >17 publications with JAG1 and Brain Diseases Tetralogy of Fallot Antibodies >17 publications with JAG1 and Tetralogy of Fallot Organs/Tissues associated with JAG1 elisa kit Organ/Tissue Name Pubmed Publications Blood Antibodies >57 publications with JAG1 and Blood Embryonic Tissue Antibodies >34 publications with JAG1 and Embryonic Tissue Brain Antibodies >33 publications with JAG1 and Brain Kidney Antibodies >21 publications with JAG1 and Kidney Lung Antibodies >11 publications with JAG1 and Lung Placenta Antibodies >9 publications with JAG1 and Placenta Connective Tissue Antibodies >9 publications with JAG1 and Connective Tissue Pancreas Antibodies >9 publications with JAG1 and Pancreas Intestine Antibodies >6 publications with JAG1 and Intestine Ovary Antibodies >5 publications with JAG1 and Ovary TOP © 2006-24 MyBioSource.com. 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