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KLK6 elisa kit :: Mouse Kallikrein 6 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS721782
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $455 +1 FREE 8GB USB
96-Strip-Wells  /  $660 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Kallikrein 6 (KLK6), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Kallikrein 6 ELISA Kit

 Product Gene Name   

KLK6 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    602652
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 Species Reactivity    Mouse
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    1.0-25ng/mL
 Sensitivity    0.1ng/mL
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of KLK6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for KLK6 purchase    MBS721782 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Kallikrein 6 (KLK6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1.0-25ng/mL in biological research samples containing KLK6, with an estimated sensitivity of 0.1ng/mL. The ELISA analytical biochemical technique of the MBS721782 kit is based on KLK6 antibody-KLK6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect KLK6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, KLK6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for KLK6 elisa kit    Signal Transduction
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 Typical Testing Data/Standard Curve (for reference only) of KLK6 elisa kit    KLK6 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS721782. Click to request current manual
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NCBI/Uniprot data below describe general gene information for KLK6. It may not necessarily be applicable to this product.
 NCBI GI #    61744426
 NCBI GeneID    5653
 NCBI Accession #    NP_001012983.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001012965.1 [Other Products]
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 UniProt Secondary Accession #    Q6H301; A6NJA1; A8MW09 [Other Products]
 UniProt Related Accession #    Q92876 [Other Products]
 Molecular Weight    4,333 Da
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 NCBI Official Full Name    kallikrein-6 isoform B
 NCBI Official Synonym Full Names    kallikrein-related peptidase 6
 NCBI Official Symbol    KLK6 [Similar Products]
 NCBI Official Synonym Symbols   
hK6; Bssp; Klk7; SP59; PRSS9; PRSS18
[Similar Products]
 NCBI Protein Information    kallikrein-6; zyme; neurosin; protease M; serine protease 9; serine protease 18
 UniProt Protein Name    Kallikrein-6
 UniProt Synonym Protein Names   
Neurosin; Protease M; SP59; Serine protease 18; Serine protease 9; Zyme
 Protein Family    Kallikrein
 UniProt Gene Name    KLK6 [Similar Products]
 UniProt Synonym Gene Names    PRSS18; PRSS9 [Similar Products]
 UniProt Entry Name    KLK6_HUMAN
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 NCBI Summary for KLK6    Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for KLK6    KLK6: Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis. Belongs to the peptidase S1 family. Kallikrein subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Protease; Secreted, signal peptide; EC 3.4.21.-; Nucleolus

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: microtubule cytoskeleton; nucleoplasm; extracellular space; intercellular bridge; nuclear membrane; mitochondrion; endoplasmic reticulum; cytoplasm; extracellular region; nucleolus

Molecular Function: protein binding; serine-type endopeptidase activity

Biological Process: myelination; protein autoprocessing; collagen catabolic process; central nervous system development; amyloid precursor protein metabolic process; tissue regeneration; regulation of cell differentiation; positive regulation of G-protein coupled receptor protein signaling pathway; response to wounding; hormone metabolic process; protein processing; proteolysis
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 Research Articles on KLK6    1. KLK6 mRNA expression could be considered as an independent, unfavorable molecular prognostic biomarker in colorectal adenocarcinoma, with additional prognostic value in patients without regional or distant metastases
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with KLK6 elisa kitPathways associated with KLK6 elisa kit
 Reference Product  PubMed Publications
 SERPINC1 elisa kit  >1 publications with KLK6 and SERPINC1
 APP elisa kit  >1 publications with KLK6 and APP
 SNCA elisa kit  >1 publications with KLK6 and SNCA
 Products by Pathway  Pathway Diagram
 Alpha-synuclein Signaling Pathway antibodies  Alpha-synuclein Signaling Pathway Diagram
Diseases associated with KLK6 elisa kitOrgans/Tissues associated with KLK6 elisa kit
 Disease Name  Pubmed Publications
 Ovarian Neoplasms Antibodies  >39 publications with KLK6 and Ovarian Neoplasms
 Carcinoma Antibodies  >33 publications with KLK6 and Carcinoma
 Nervous System Diseases Antibodies  >28 publications with KLK6 and Nervous System Diseases
 Brain Diseases Antibodies  >19 publications with KLK6 and Brain Diseases
 Breast Neoplasms Antibodies  >17 publications with KLK6 and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >12 publications with KLK6 and Neoplasm Metastasis
 Disease Models, Animal Antibodies  >11 publications with KLK6 and Disease Models, Animal
 Inflammation Antibodies  >10 publications with KLK6 and Inflammation
 Neoplasms, Experimental Antibodies  >7 publications with KLK6 and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >4 publications with KLK6 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >34 publications with KLK6 and Brain
 Ascites Antibodies  >13 publications with KLK6 and Ascites
 Spinal Cord Antibodies  >9 publications with KLK6 and Spinal Cord
 Ovary Antibodies  >8 publications with KLK6 and Ovary
 Lymph Node Antibodies  >6 publications with KLK6 and Lymph Node
 Kidney Antibodies  >5 publications with KLK6 and Kidney
 Stomach Antibodies  >5 publications with KLK6 and Stomach
 Lung Antibodies  >5 publications with KLK6 and Lung
 Mammary Gland Antibodies  >4 publications with KLK6 and Mammary Gland
 Pancreas Antibodies  >4 publications with KLK6 and Pancreas
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