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LBP elisa kit :: Mouse LBP ELISA Kit

Scan QR to view Datasheet Catalog #    MBS825103
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
96 Tests  /  $470 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LBP, ELISA Kit

★Popular Item★
 Also Known As   

Mouse LBP ELISA Kit

 Product Synonym Names    Lipopolysaccharide-binding protein; LBP
 Product Gene Name   

LBP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q61805
 Species Reactivity    Mouse
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 Specificity    The Mouse LBP ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Mouse LBP proteins within the range of 1560 pg/ml - 100000 pg/ml.
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 Samples    Cell Culture Supernatants, Serum, Plasma.
 Assay Type    Sandwich
 Sensitivity    The minimum detectable dose of Mouse LBP is typically less than 50 pg/ml.
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 Preparation and Storage    Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of LBP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for LBP purchase    MBS825103 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the LBP, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LBP, with an estimated sensitivity of The minimum detectable dose of Mouse LBP is typically less than 50 pg/ml. The ELISA analytical biochemical technique of the MBS825103 kit is based on LBP antibody-LBP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LBP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LBP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Cell Culture Supernatants, Serum, Plasma. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for LBP elisa kit

   Principle of the Assay: Lipopolysaccharide binding protein is a protein that in humans is encoded by the LBP gene. This gene is mapped to 20q11.23. LBP is a soluble acute-phase protein that binds to bacterial lipopolysaccharide (or LPS) to elicit immune responses by presenting the LPS to important cell surface pattern recognition receptors called CD14 and TLR4. It is present in the cerebrospinal fluid of patients with pneumococcal meningitis. The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. LBP is made in the liver during the acute phase of infections and is thought to function as a carrier for LPS and to help control LPS-dependent monocyte responses.

Background/Introduction: Sandwich Enzyme-Linked Immunosorbent Assay for Quantitative Detection of Mouse LBP Concentrations in Cell Culture Supernatants, Serum, Plasma.
 Applications Tested/Suitable for LBP elisa kit   

Sandwich ELISA (SE)

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 Typical Testing Data/Standard Curve (for reference only) of LBP elisa kit   
LBP elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS825103. Click to request current manual
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NCBI/Uniprot data below describe general gene information for LBP. It may not necessarily be applicable to this product.
 NCBI GI #    113865991
 NCBI GeneID    16803
 NCBI Accession #    NP_032515.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_008489.2 [Other Products]
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 UniProt Primary Accession #    Q61805 [Other Products]
 UniProt Secondary Accession #    Q99KA0; A2AC66 [Other Products]
 UniProt Related Accession #    Q61805 [Other Products]
 Molecular Weight    53,055 Da
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 NCBI Official Full Name    lipopolysaccharide-binding protein
 NCBI Official Synonym Full Names    lipopolysaccharide binding protein
 NCBI Official Symbol    Lbp [Similar Products]
 NCBI Official Synonym Symbols   
Ly88; Bpifd2
[Similar Products]
 NCBI Protein Information    lipopolysaccharide-binding protein
 UniProt Protein Name    Lipopolysaccharide-binding protein
 Protein Family    Lipopolysaccharide-binding protein
 UniProt Gene Name    Lbp [Similar Products]
 UniProt Synonym Gene Names    LBP [Similar Products]
 UniProt Entry Name    LBP_MOUSE
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 UniProt Comments for LBP    LBP: Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. The LBP/LPS complex seems to interact with the CD14 receptor. Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; cell surface; extracellular region

Molecular Function: lipopolysaccharide binding; lipid binding; receptor binding

Biological Process: positive regulation of tumor necrosis factor biosynthetic process; immune system process; detection of molecule of bacterial origin; positive regulation of toll-like receptor 4 signaling pathway; positive regulation of interleukin-6 production; response to lipopolysaccharide; negative regulation of tumor necrosis factor production; positive regulation of tumor necrosis factor production; defense response to Gram-negative bacterium; lipid transport; leukocyte chemotaxis during inflammatory response; positive regulation of chemokine production; positive regulation of interleukin-8 production; lipopolysaccharide transport; defense response to Gram-positive bacterium; transport; macrophage activation during immune response; defense response to bacterium; acute-phase response; lipopolysaccharide-mediated signaling pathway; innate immune response; positive regulation of phagocytosis, engulfment; positive regulation of macrophage activation
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 Research Articles on LBP    1. findings describe a novel role for LBP in normal hippocampal development and raise the possibility that some of the behavioral sequelae of early life stress are mediated by reduced expression of LBP during a critical period of neurodevelopment.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with LBP elisa kitDiseases associated with LBP elisa kit
 Products by Pathway  Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 NF-kappa B Signaling Pathway antibodies  NF-kappa B Signaling Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Toll Like Receptor 4 (TLR4) Cascade Pathway antibodies  Toll Like Receptor 4 (TLR4) Cascade Pathway Diagram
 Toll-Like Receptors Cascades Pathway antibodies  Toll-Like Receptors Cascades Pathway Diagram
 Toll-like Receptor Signaling Pathway antibodies  Toll-like Receptor Signaling Pathway Diagram
 Toll-like Receptor Signaling Pathway antibodies  Toll-like Receptor Signaling Pathway Diagram
 Transfer Of LPS From LBP Carrier To CD14 Pathway antibodies  Transfer Of LPS From LBP Carrier To CD14 Pathway Diagram
 Disease Name  Pubmed Publications
 Pain Antibodies  >3030 publications with LBP and Pain
 Nervous System Diseases Antibodies  >2438 publications with LBP and Nervous System Diseases
 Inflammation Antibodies  >339 publications with LBP and Inflammation
 Necrosis Antibodies  >245 publications with LBP and Necrosis
 Sepsis Antibodies  >171 publications with LBP and Sepsis
 Liver Diseases Antibodies  >77 publications with LBP and Liver Diseases
 Obesity Antibodies  >68 publications with LBP and Obesity
 Carcinoma Antibodies  >48 publications with LBP and Carcinoma
 Brain Diseases Antibodies  >48 publications with LBP and Brain Diseases
 Hypertension Antibodies  >42 publications with LBP and Hypertension
Organs/Tissues associated with LBP elisa kit
 Organ/Tissue Name  Pubmed Publications
 Other Antibodies  >938 publications with LBP and Other
 Blood Antibodies  >703 publications with LBP and Blood
 Bone Antibodies  >556 publications with LBP and Bone
 Joint Antibodies  >242 publications with LBP and Joint
 Liver Antibodies  >172 publications with LBP and Liver
 Lung Antibodies  >116 publications with LBP and Lung
 Brain Antibodies  >99 publications with LBP and Brain
 Kidney Antibodies  >51 publications with LBP and Kidney
 Spinal Cord Antibodies  >34 publications with LBP and Spinal Cord
 Connective Tissue Antibodies  >31 publications with LBP and Connective Tissue
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