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LRBA elisa kit :: Mouse LPS-responsive vesicle trafficking, beach and anchor containing ELISA Kit

Scan QR to view Datasheet Catalog #    MBS902174
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LPS-responsive vesicle trafficking, beach and anchor containing (LRBA), ELISA Kit

 Also Known As   

Mouse Lipopolysaccharide-responsive and beige-like anchor protein, LRBA ELISA Kit

 Product Synonym Names    Mouse Lipopolysaccharide-responsive and beige-like anchor protein (LRBA) ELISA kit; BGL; CDC4L; DKFZp686A09128; DKFZp686K03100; DKFZp686P2258; FLJ16600; FLJ25686; LAB300; LBA; MGC72098; cell division cycle 4-like; vesicle trafficking; beach and anchor containing; LPS-responsive vesicle trafficking; beach and anchor containing
 Product Gene Name   

LRBA elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS902174 Testing Data    Testing Data PDF
 3D Structure    ModBase 3D Structure for Q9ESE1
 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Mouse LRBA. No significant cross-reactivity or interference between Mouse LRBA and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Assay Type    Sandwich
 Detection Range    31.25 pg/ml-2000 pg/ml
 Sensitivity    7.81 pg/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of LRBA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for LRBA purchase    MBS902174 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the LPS-responsive vesicle trafficking, beach and anchor containing (LRBA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.25 pg/ml-2000 pg/ml in biological research samples containing LRBA, with an estimated sensitivity of 7.81 pg/ml. The ELISA analytical biochemical technique of the MBS902174 kit is based on LRBA antibody-LRBA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LRBA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LRBA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for LRBA elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for LRBA has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any LRBA present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for LRBA is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of LRBA bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of LRBA elisa kit    LRBA elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS902174. Click to request current manual
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NCBI/Uniprot data below describe general gene information for LRBA. It may not necessarily be applicable to this product.
 NCBI GI #    117956395
 NCBI GeneID    80877
 NCBI Accession #    NP_001071155.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001077687.1 [Other Products]
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 UniProt Primary Accession #    Q9ESE1 [Other Products]
 UniProt Secondary Accession #    Q9ESD3; Q9ESD4 [Other Products]
 UniProt Related Accession #    Q9ESE1 [Other Products]
 Molecular Weight    317,064 Da
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 NCBI Official Full Name    lipopolysaccharide-responsive and beige-like anchor protein isoform gamma
 NCBI Official Synonym Full Names    LPS-responsive beige-like anchor
 NCBI Official Symbol    Lrba [Similar Products]
 NCBI Official Synonym Symbols   
Lba; C80285; Lab300; D3Ertd775e
[Similar Products]
 NCBI Protein Information    lipopolysaccharide-responsive and beige-like anchor protein; beige-like protein
 UniProt Protein Name    Lipopolysaccharide-responsive and beige-like anchor protein
 UniProt Synonym Protein Names   
Beige-like protein
 Protein Family    Lipopolysaccharide-responsive and beige-like anchor protein
 UniProt Gene Name    Lrba [Similar Products]
 UniProt Synonym Gene Names    Bgl; Lba [Similar Products]
 UniProt Entry Name    LRBA_MOUSE
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 UniProt Comments for LRBA    LRBA: May be involved in coupling signal transduction and vesicle trafficking to enable polarized secretion and/or membrane deposition of immune effector molecules. Defects in LRBA are the cause of immunodeficiency, common variable, type 8, with autoimmunity (CVID8). An autosomal recessive immunologic disorder associated with defective B-cell differentiation and decreased or absent antibody production. Affected individuals have early-childhood onset of recurrent infections, particularly respiratory infections, and also develop variable autoimmune disorders, including idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia, and inflammatory bowel disease. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: Golgi apparatus; extrinsic to membrane; membrane; cell; endoplasmic reticulum; lysosome; cytoplasmic membrane-bound vesicle; integral to membrane; plasma membrane; intracellular; trans-Golgi network

Molecular Function: protein kinase A binding; phospholipid binding

Biological Process: protein localization; endosome transport; signal transduction
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with LRBA elisa kitOrgans/Tissues associated with LRBA elisa kit
 Disease Name  Pubmed Publications
 Skin Diseases Antibodies  >2 publications with LRBA and Skin Diseases
 Breast Neoplasms Antibodies  >2 publications with LRBA and Breast Neoplasms
 Neoplasms Antibodies  >2 publications with LRBA and Neoplasms
 Hematologic Diseases Antibodies  >2 publications with LRBA and Hematologic Diseases
 Congenital Abnormalities Antibodies  >1 publications with LRBA and Congenital Abnormalities
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >2 publications with LRBA and Eye
 Brain Antibodies  >1 publications with LRBA and Brain
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