NP_001277415.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,343 Da
NCBI Official Full Name
lysophosphatidic acid receptor 1 isoform 2
NCBI Official Synonym Full Names
lysophosphatidic acid receptor 1
NCBI Official Synonym Symbols
Edg2; Kdt2; lpA1; vzg-1; Gpcr26; AI326300 [Similar Products]
NCBI Protein Information
lysophosphatidic acid receptor 1
UniProt Protein Name
Lysophosphatidic acid receptor 1
UniProt Synonym Protein Names
Lysophosphatidic acid receptor Edg-2
UniProt Synonym Gene Names
UniProt Entry Name
LPAR1_MOUSE
UniProt Comments for Lpar1
LPAR1: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1
Cellular Component: cell soma; cell surface; cytoplasm; cytosol; dendritic shaft; dendritic spine; endocytic vesicle; endosome; integral to membrane; integral to plasma membrane; membrane; neuron projection; plasma membrane
Molecular Function: G-protein alpha-subunit binding; G-protein coupled receptor activity; PDZ domain binding; phospholipid binding; protein binding; signal transducer activity
Biological Process: activation of MAPK activity; bleb formation; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; negative regulation of cAMP biosynthetic process; phospholipase C activation; positive regulation of apoptosis; positive regulation of MAPKKK cascade; positive regulation of Rho protein signal transduction; positive regulation of stress fiber formation; regulation of cell shape; signal transduction
Research Articles on Lpar1
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Pathways associated with Lpar1 elisa kit
Diseases associated with Lpar1 elisa kit
Organs/Tissues associated with Lpar1 elisa kit
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