NP_001273110.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
46,701 Da
NCBI Official Full Name
protein-lysine 6-oxidase preproprotein
NCBI Official Synonym Full Names
lysyl oxidase
NCBI Protein Information
protein-lysine 6-oxidase
UniProt Protein Name
Protein-lysine 6-oxidase
UniProt Synonym Protein Names
Lysyl oxidase; Ras excision protein
UniProt Synonym Gene Names
NCBI Summary for LOX
This gene encodes a precursor protein that belongs to the lysyl oxidase family of proteins. The secreted proprotein is proteolytically processed to an active mature peptide and a propeptide. This propeptide is thought to function in tumor suppression by inhibiting the Ras signaling pathway. The active enzyme plays a role in cross-linking of collagen and elastin and is essential for development of cardiovascular and respiratory systems, and development of skin and connective tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
UniProt Comments for LOX
Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin.
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Products associated with LOX elisa kit
Pathways associated with LOX elisa kit
Diseases associated with LOX elisa kit
Organs/Tissues associated with LOX elisa kit
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