NP_067395.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
55,541 Da
NCBI Official Full Name
serine/threonine-protein kinase 4
NCBI Official Synonym Full Names
serine/threonine kinase 4
NCBI Official Synonym Symbols
Mst1; Ysk3; Kas-2; AI447339; AU020804 [Similar Products]
NCBI Protein Information
serine/threonine-protein kinase 4; MST-1; STE20-like kinase MST1; sterile 20-like kinase 1; Yeast Sps1/Ste20-related kinase 3; mammalian STE20-like protein kinase 1
UniProt Protein Name
Serine/threonine-protein kinase 4
UniProt Synonym Protein Names
Mammalian STE20-like protein kinase 1; MST-1; STE20-like kinase MST1Cleaved into the following 2 chains:Serine/threonine-protein kinase 4 37kDa subunit; MST1/N; Serine/threonine-protein kinase 4 18kDa subunit; MST1/C
UniProt Synonym Gene Names
UniProt Entry Name
STK4_MOUSE
UniProt Comments for STK4
MST1: a protein kinase of the STE20 family. Proteolytically activated by caspase during apoptosis. Activated by apoptotic signals as well as other stress conditions. Full activation requires both phosphorylation and caspase-mediated cleavage. Phosphorylation at serine 327 of Mst1, which is close to the caspase-3 recognition site, inhibits caspase-mediated cleavage.
Protein type: Autophagy; Protein kinase, Ser/Thr (non-receptor); Protein kinase, STE; Kinase, protein; EC 2.7.11.1; STE group; STE20 family; MST subfamily
Cellular Component: nucleoplasm; cytoplasm; intracellular; nucleus
Molecular Function: protein dimerization activity; identical protein binding; protein homodimerization activity; metal ion binding; magnesium ion binding; nucleotide binding; transcription factor binding; protein kinase activity; transferase activity; protein serine/threonine kinase activity; protein binding; transferase activity, transferring phosphorus-containing groups; kinase activity; ATP binding; receptor signaling protein serine/threonine kinase activity
Biological Process: central nervous system development; positive regulation of protein binding; positive regulation of apoptosis; apoptosis; protein amino acid autophosphorylation; cell morphogenesis; negative regulation of organ growth; signal transduction; protein amino acid phosphorylation; patterning of blood vessels; keratinocyte differentiation; negative regulation of cell proliferation; peptidyl-serine phosphorylation; response to stress; positive regulation of fat cell differentiation; neural tube formation; phosphorylation
Research Articles on STK4
Precautions
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Disclaimer
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Pathways associated with STK4 elisa kit
Diseases associated with STK4 elisa kit
Organs/Tissues associated with STK4 elisa kit
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