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BMPG elisa kit :: Mouse Major Basic Protein (MBP) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9309876 BMPG elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Major Basic Protein (MBP) (BMPG), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Major Basic Protein (MBP) ELISA Kit

 Product Gene Name   

BMPG elisa kit

[Similar Products]
 Product Synonym Gene Name    PRG2; BMPG; Proteoglycan 2; Bone Marrow,Natural Killer Cell Activator; [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 11; NC_000011.10 (57387361..57390657, complement). Location: 11q12
 OMIM    605601
 3D Structure    ModBase 3D Structure for P13727
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 Species Reactivity    Mouse
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Sandwich
 Detection Range    0.625 ng/ml - 20 ng/ml.
 Sensitivity    0.1 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of BMPG elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for BMPG purchase    MBS9309876 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Major Basic Protein (MBP) (BMPG) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.625 ng/ml - 20 ng/ml in biological research samples containing BMPG, with an estimated sensitivity of 0.1 ng/ml. The ELISA analytical biochemical technique of the MBS9309876 kit is based on BMPG antibody-BMPG antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BMPG antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BMPG. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for BMPG elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MBP (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9309876. Click to request current manual
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NCBI/Uniprot data below describe general gene information for BMPG. It may not necessarily be applicable to this product.
 NCBI GI #    187415
 NCBI GeneID    5553
 NCBI Accession #    AAA36203.1 [Other Products]
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 UniProt Primary Accession #    P13727 [Other Products]
 UniProt Secondary Accession #    P81448; Q14227; Q6ICT2 [Other Products]
 UniProt Related Accession #    P13727 [Other Products]
 Molecular Weight    25,206 Da
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 NCBI Official Full Name    major basic protein
 NCBI Official Synonym Full Names    proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
 NCBI Official Symbol    PRG2 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    bone marrow proteoglycan; bone-marrow proteoglycan; proteoglycan 2 preproprotein; natural killer cell activator; eosinophil major basic protein; eosinophil granule major basic protein
 UniProt Protein Name    Bone marrow proteoglycan
 UniProt Synonym Protein Names   
Proteoglycan 2Cleaved into the following chain:Eosinophil granule major basic protein; EMBP; MBP; Alternative name(s):; Pregnancy-associated major basic protein
 UniProt Gene Name    PRG2 [Similar Products]
 UniProt Synonym Gene Names    MBP; BMPG; EMBP; MBP [Similar Products]
 UniProt Entry Name    PRG2_HUMAN
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 NCBI Summary for BMPG    The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
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 UniProt Comments for BMPG    PRG2: Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.

Protein type: Secreted, signal peptide; Vesicle; Secreted

Chromosomal Location of Human Ortholog: 11q12

Cellular Component: transport vesicle; extracellular region

Molecular Function: heparin binding; carbohydrate binding

Biological Process: positive regulation of interleukin-4 production; negative regulation of interleukin-10 production; defense response to bacterium; immune response; defense response to nematode
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 Research Articles on BMPG    1. During pregnancy, the proform of eosinophil major basic protein-angiotensinogen constitutes the major form in late pregnancy.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with BMPG elisa kitPathways associated with BMPG elisa kit
 Reference Product  PubMed Publications
 AGT elisa kit  >2 publications with BMPG and AGT
 EPX elisa kit  >1 publications with BMPG and EPX
 PAPPA elisa kit  >1 publications with BMPG and PAPPA
 Products by Pathway  Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
Diseases associated with BMPG elisa kitOrgans/Tissues associated with BMPG elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >7 publications with BMPG and Neoplasms
 Immune System Diseases Antibodies  >4 publications with BMPG and Immune System Diseases
 Pancreatic Neoplasms Antibodies  >2 publications with BMPG and Pancreatic Neoplasms
 Inflammation Antibodies  >2 publications with BMPG and Inflammation
 Carcinoma Antibodies  >2 publications with BMPG and Carcinoma
 Kidney Diseases Antibodies  >1 publications with BMPG and Kidney Diseases
 Lymphoma Antibodies  >1 publications with BMPG and Lymphoma
 Ovarian Neoplasms Antibodies  >1 publications with BMPG and Ovarian Neoplasms
 Lung Neoplasms Antibodies  >1 publications with BMPG and Lung Neoplasms
 Chromosome Aberrations Antibodies  >1 publications with BMPG and Chromosome Aberrations
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >28 publications with BMPG and Blood
 Bone Marrow Antibodies  >5 publications with BMPG and Bone Marrow
 Heart Antibodies  >1 publications with BMPG and Heart
 Vascular Antibodies  >1 publications with BMPG and Vascular
 Intestine Antibodies  >1 publications with BMPG and Intestine
 Placenta Antibodies  >1 publications with BMPG and Placenta
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