CAH71176.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56,554 Da
NCBI Official Full Name
mannose receptor, C type 1-like 1
NCBI Official Synonym Full Names
mannose receptor, C type 1
NCBI Official Synonym Symbols
MMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1 [Similar Products]
NCBI Protein Information
macrophage mannose receptor 1
UniProt Protein Name
Macrophage mannose receptor 1
UniProt Synonym Protein Names
C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1; CD_antigen: CD206
UniProt Synonym Gene Names
UniProt Entry Name
MRC1_HUMAN
NCBI Summary for MRC1
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Apr 2011]
UniProt Comments for MRC1
MRC1: Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor, misc.; Membrane protein, integral; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 10p12.33
Cellular Component: cell surface; integral to plasma membrane; plasma membrane; endosome membrane
Molecular Function: mannose binding; protein binding; transmembrane receptor activity; receptor activity
Biological Process: receptor-mediated endocytosis; signal transduction
Research Articles on MRC1
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Pathways associated with MRC1 elisa kit
Diseases associated with MRC1 elisa kit
Organs/Tissues associated with MRC1 elisa kit
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