View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List MGP elisa kit :: Mouse Matrix Gla Protein (MGP) ELISA Kit Catalog # MBS269627 Unit / Price 48-Strip-Wells / $305 +1 FREE 8GB USB 96-Strip-Wells / $460 +1 FREE 8GB USB 5x96-Strip-Wells / $1,890 +2 FREE 8GB USB 10x96-Strip-Wells / $3,470 +4 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Matrix Gla Protein (MGP), ELISA Kit Popular Item Full Product Name Mouse Matrix Gla Protein (MGP) ELISA Kit Product Gene Name MGP elisa kit[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sample Manual Insert Download Sample PDF Manual View Sample PDF Manual OMIM gene 245150 Species Reactivity Mouse Specificity No cross-reaction with other factors. Samples Mouse serum, plasma or cell culture supernatant Assay Type Quantitative Sandwich Detection Range 5000 pg/mL-78 pg/mL Sensitivity Up to 20 pg/mL Intra-assay Precision <= 8% Inter-assay Precision <= 12% Preparation and Storage Store all reagents at 2-8 degree C. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Product Note Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details. Other Notes Small volumes of MGP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. Searchable Terms for MGP purchase MBS269627 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Matrix Gla Protein (MGP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MGP. The ELISA analytical biochemical technique of the MBS269627 kit is based on MGP antibody-MGP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MGP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MGP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%). TOP Related Product Information for MGP elisa kit Principle of the Assay: As mentioned above, this kit utilizes the Double Antibody Sandwich ELISA technique. The pre-coated antibody is an anti-Mouse MGP monoclonal antibody, while the detection antibody is a biotinylated polyclonal antibody. Samples and biotinylated antibodies are added into ELISA plate wells and washed out with PBS or TBS after their respective additions to the wells. Then Avidin-peroxidase conjugates are added to the wells in after. TMB substrate is used for coloration after the enzyme conjugate has already been thoroughly washed out of the wells by PBS or TBS. TMB reacts to form a blue product from the peroxidase activity, and finally turns to yellow after addition of the stop solution (Color Reagent C). The color intensity and quantity of target analyte in the sample are positively correlated. Typical Testing Data/Standard Curve (for reference only) of MGP elisa kit TOP Sample Manual Insert of MBS269627. NCBI/Uniprot data below describe general gene information for MGP. It may not necessarily be applicable to this product. NCBI GI # 187591 NCBI GeneID 4256 NCBI Accession # AAB53765.1 [Other Products] UniProt Secondary Accession # Q2TU41; Q567P9; Q6ICN5; A0M8W5; B2R519; J3KMX7[Other Products] UniProt Related Accession # P08493[Other Products] Molecular Weight 15,325 Da TOP NCBI Official Full Name matrix Gla protein NCBI Official Synonym Full Names matrix Gla protein NCBI Official Symbol MGP [Similar Products] NCBI Official Synonym Symbols NTI; GIG36; MGLAP [Similar Products] NCBI Protein Information matrix Gla protein; cell growth-inhibiting gene 36 protein UniProt Protein Name Matrix Gla protein UniProt Synonym Protein Names Cell growth-inhibiting gene 36 protein Protein Family Matrix Gla protein UniProt Gene Name MGP [Similar Products] UniProt Synonym Gene Names MGLAP; GIG36; MGP [Similar Products] UniProt Entry Name MGP_HUMAN TOP NCBI Summary for MGP The protein encoded by this gene is secreted and likely acts as an inhibitor of bone formation. The encoded protein is found in the organic matrix of bone and cartilage. Defects in this gene are a cause of Keutel syndrome (KS). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] TOP UniProt Comments for MGP MGP: Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. Defects in MGP are the cause of Keutel syndrome (KS). KS is an autosomal recessive disorder characterized by abnormal cartilage calcification, peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia. Belongs to the osteocalcin/matrix Gla protein family.Protein type: Secreted, signal peptide; Secreted; Extracellular matrixChromosomal Location of Human Ortholog: 12p12.3Cellular Component: extracellular matrix; proteinaceous extracellular matrixMolecular Function: protein binding; structural constituent of bone; extracellular matrix structural constituent; calcium ion bindingBiological Process: ossification; cell differentiation; regulation of bone mineralization; cartilage condensationDisease: Keutel Syndrome Research Articles on MGP 1. The MGP-138CC genotype may be associated with slower progression of vascular calcification in maintenance hemodialysis patients TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with MGP elisa kit Reference Product PubMed Publications JUN elisa kit >63 publications with MGP and JUN BMP2 elisa kit >32 publications with MGP and BMP2 PTH elisa kit >11 publications with MGP and PTH VEGFA elisa kit >5 publications with MGP and VEGFA TGFBI elisa kit >1 publications with MGP and TGFBI JUNB elisa kit >1 publications with MGP and JUNB Pathways associated with MGP elisa kit Products by Pathway Pathway Diagram Endochondral Ossification Pathway antibodies Endochondral Ossification Pathway Diagram Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway antibodies Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway Diagram Diseases associated with MGP elisa kit Disease Name Pubmed Publications Vascular Calcification Antibodies >146 publications with MGP and Vascular Calcification Cardiovascular Diseases Antibodies >140 publications with MGP and Cardiovascular Diseases Heart Diseases Antibodies >62 publications with MGP and Heart Diseases Kidney Diseases Antibodies >60 publications with MGP and Kidney Diseases Neoplasms Antibodies >50 publications with MGP and Neoplasms Atherosclerosis Antibodies >43 publications with MGP and Atherosclerosis Nervous System Diseases Antibodies >27 publications with MGP and Nervous System Diseases Inflammation Antibodies >26 publications with MGP and Inflammation Drug Toxicity Antibodies >23 publications with MGP and Drug Toxicity Carcinoma Antibodies >19 publications with MGP and Carcinoma Organs/Tissues associated with MGP elisa kit Organ/Tissue Name Pubmed Publications Bone Antibodies >232 publications with MGP and Bone Vascular Antibodies >194 publications with MGP and Vascular Blood Antibodies >166 publications with MGP and Blood Muscle Antibodies >106 publications with MGP and Muscle Kidney Antibodies >94 publications with MGP and Kidney Connective Tissue Antibodies >82 publications with MGP and Connective Tissue Heart Antibodies >60 publications with MGP and Heart Lung Antibodies >39 publications with MGP and Lung Liver Antibodies >39 publications with MGP and Liver Brain Antibodies >37 publications with MGP and Brain TOP © 2006-24 MyBioSource.com. 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