NP_001139431.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,789 Da
NCBI Official Full Name
protein NDRG2 isoform 2
NCBI Official Synonym Full Names
N-myc downstream regulated gene 2
NCBI Protein Information
protein NDRG2; protein Ndr2; N-myc downstream regulated 2; N-myc downstream-regulated gene 2 protein
UniProt Protein Name
Protein NDRG2
UniProt Synonym Protein Names
N-myc downstream-regulated gene 2 protein; Protein Ndr2
UniProt Synonym Gene Names
UniProt Entry Name
NDRG2_MOUSE
UniProt Comments for NDRG2
NDRG2: a pro-apoptotic protein that may be involved in dendritic cell and neuron differentiation. May have anti-tumor activity. Generally not expressed in tumor cell lines. Unlike Ndr1, Ndr2 and Ndr3 appear not to be controlled by N-myc or c-myc. The loss of NDRG2 expression has been shown to be a prognostic indicator in gastric carcinomas. Five isoforms of the human protein are produced by alternative splicing. Isoforms 1 and 2 are present in brain neurons and up-regulated in Alzheimer disease
Protein type: Tumor suppressor; Apoptosis
Cellular Component: nucleoplasm; Golgi apparatus; centrosome; cell projection; cytoplasm; microtubule organizing center; nucleus
Biological Process: nervous system development; Wnt receptor signaling pathway; negative regulation of smooth muscle cell proliferation; multicellular organismal development; negative regulation of cytokine production; cell differentiation; signal transduction
Research Articles on NDRG2
Precautions
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Disclaimer
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Diseases associated with NDRG2 elisa kit
Organs/Tissues associated with NDRG2 elisa kit
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