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NT-4 elisa kit :: Mouse NT-4 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2505246
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NT-4, ELISA Kit

★Popular Item★
 Also Known As   

Mouse NT-4 (Neurotrophin 4) ELISA Kit

 Product Gene Name   

NT-4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    162662
 3D Structure    ModBase 3D Structure for P34130
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 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Mouse NT-4. No significant cross-reactivity or interference between Mouse NT-4 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Mouse NT-4 and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    15.625--1000pg/mL
 Sensitivity    9.375pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of NT-4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NT-4 purchase    MBS2505246 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the NT-4, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.625--1000pg/mL in biological research samples containing NT-4, with an estimated sensitivity of 9.375pg/mL. The ELISA analytical biochemical technique of the MBS2505246 kit is based on NT-4 antibody-NT-4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NT-4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NT-4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for NT-4 elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of NT-4 in Mouse serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse NT-4. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Mouse NT-4 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse NT-4, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Mouse NT-4. You can calculate the concentration of Mouse NT-4 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of NT-4 elisa kit    NT-4 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2505246. Click to request current manual
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NCBI/Uniprot data below describe general gene information for NT-4. It may not necessarily be applicable to this product.
 NCBI GI #    5453808
 NCBI GeneID    4909
 NCBI Accession #    NP_006170.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006179.4 [Other Products]
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 UniProt Primary Accession #    P34130 [Other Products]
 UniProt Secondary Accession #    Q6FH56 [Other Products]
 UniProt Related Accession #    P34130; AAB20549 [Other Products]
 Molecular Weight    22,427 Da
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 NCBI Official Full Name    neurotrophin-4 preproprotein
 NCBI Official Synonym Full Names    neurotrophin 4
 NCBI Official Symbol    NTF4 [Similar Products]
 NCBI Official Synonym Symbols   
NT4; NT5; NT-4; NT-5; NTF5; GLC10; GLC1O; NT-4/5
[Similar Products]
 NCBI Protein Information    neurotrophin-4; neurotrophic factor 4; neurotrophic factor 5; neurotrophin 5 (neurotrophin 4/5); neurotrophin-5; neutrophic factor 4
 UniProt Protein Name    Neurotrophin-4
 UniProt Synonym Protein Names   
Neurotrophin-5; NT-5; Neutrophic factor 4
 UniProt Gene Name    NTF4 [Similar Products]
 UniProt Synonym Gene Names    NTF5; NT-4; NT-5 [Similar Products]
 UniProt Entry Name    NTF4_HUMAN
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 NCBI Summary for NT-4    This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood. [provided by RefSeq, Jul 2008]
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 UniProt Comments for NT-4    NT-4/5: Target-derived survival factor for peripheral sensory sympathetic neurons. Defects in NTF4 may be associated with susceptibility to primary open angle glaucoma type 1O (GLC1O). A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place. Belongs to the NGF-beta family.

Protein type: Cytokine; Secreted, signal peptide; Cell development/differentiation; Secreted

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: endoplasmic reticulum lumen; cytoplasmic membrane-bound vesicle; extracellular region

Molecular Function: neurotrophin p75 receptor binding; growth factor activity

Biological Process: mechanoreceptor differentiation; epidermis development; long-term memory; cell-cell signaling; regulation of neuron differentiation; adult locomotory behavior; sensory organ boundary specification; ganglion mother cell fate determination; negative regulation of neuron apoptosis; neurite morphogenesis; transmembrane receptor protein tyrosine kinase signaling pathway

Disease: Glaucoma 1, Open Angle, O
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 Research Articles on NT-4    1. Patients with mastocytosis featured elevated serum levels of NGF, NT-3, and NT-4. TrkA, TrkB, and TrkC expression was also elevated.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NT-4 elisa kitPathways associated with NT-4 elisa kit
 Reference Product  PubMed Publications
 BDNF elisa kit  >14 publications with NT-4 and BDNF
 NTRK2 elisa kit  >7 publications with NT-4 and NTRK2
 NTRK1 elisa kit  >4 publications with NT-4 and NTRK1
 NGFR elisa kit  >3 publications with NT-4 and NGFR
 NTRK3 elisa kit  >2 publications with NT-4 and NTRK3
 Products by Pathway  Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Neurotrophic Factor-mediated Trk Receptor Signaling Pathway antibodies  Neurotrophic Factor-mediated Trk Receptor Signaling Pathway Diagram
 Neurotrophin Signaling Pathway antibodies  Neurotrophin Signaling Pathway Diagram
 Neurotrophin Signaling Pathway antibodies  Neurotrophin Signaling Pathway Diagram
 P75(NTR)-mediated Signaling Pathway antibodies  P75(NTR)-mediated Signaling Pathway Diagram
Diseases associated with NT-4 elisa kitOrgans/Tissues associated with NT-4 elisa kit
 Disease Name  Pubmed Publications
 Nerve Degeneration Antibodies  >2 publications with NT-4 and Nerve Degeneration
 Carcinoma Antibodies  >1 publications with NT-4 and Carcinoma
 Nervous System Diseases Antibodies  >1 publications with NT-4 and Nervous System Diseases
 Hypersensitivity Antibodies  >1 publications with NT-4 and Hypersensitivity
 Lung Diseases Antibodies  >1 publications with NT-4 and Lung Diseases
 Leukemia Antibodies  >1 publications with NT-4 and Leukemia
 Inflammation Antibodies  >1 publications with NT-4 and Inflammation
 Neoplasm Metastasis Antibodies  >1 publications with NT-4 and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >1 publications with NT-4 and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >2 publications with NT-4 and Ovary
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