AAF76980.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,358 Da
NCBI Official Full Name
neurokinin B
NCBI Official Synonym Full Names
tachykinin 3
NCBI Official Synonym Symbols
NKB; HH10; NKNB; PRO1155; ZNEUROK1 [Similar Products]
NCBI Protein Information
tachykinin-3; neurokinin b; neuromedin K; gamma tachykinin 3; preprotachykinin B; preprotachykinin-B
UniProt Protein Name
Tachykinin-3
UniProt Synonym Protein Names
ZNEUROK1Cleaved into the following chain:Neurokinin-B; NKBAlternative name(s):Neuromedin-K
UniProt Synonym Gene Names
UniProt Entry Name
TKNK_HUMAN
NCBI Summary for NKB
This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded protein is primarily expressed in the central and peripheral nervous system and functions as a neurotransmitter. This protein is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
UniProt Comments for NKB
TAC3: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12q13.3
Cellular Component: extracellular space; extracellular region
Molecular Function: protein binding; receptor binding
Biological Process: tachykinin signaling pathway; neuropeptide signaling pathway; female pregnancy
Disease: Hypogonadotropic Hypogonadism 10 With Or Without Anosmia
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Pathways associated with NKB elisa kit
Diseases associated with NKB elisa kit
Organs/Tissues associated with NKB elisa kit
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