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NE elisa kit :: Mouse Norepinephrine (NE) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9346061 NE elisa kit
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 Product Name   

Norepinephrine (NE), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Norepinephrine (NE) ELISA Kit

 Product Gene Name   

NE elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    163970
 3D Structure    ModBase 3D Structure for P23975
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 Species Reactivity    Mouse
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Body fluids, tissue homogenates, secretions or feces samples
 Assay Type    Quantitative Sandwich
 Detection Range    0.625 ng/ml - 20 ng/ml
 Sensitivity    0.1 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of NE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NE purchase    MBS9346061 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Norepinephrine (NE) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.625 ng/ml - 20 ng/ml in biological research samples containing NE, with an estimated sensitivity of 0.1 ng/ml. The ELISA analytical biochemical technique of the MBS9346061 kit is based on NE antibody-NE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NE antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NE. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for NE elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of NE (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9346061. Click to request current manual
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NCBI/Uniprot data below describe general gene information for NE. It may not necessarily be applicable to this product.
 NCBI GI #    1143479
 NCBI GeneID    6530
 NCBI Accession #    CAA62566.1 [Other Products]
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 UniProt Primary Accession #    P23975 [Other Products]
 UniProt Secondary Accession #    Q96KH8; B2R707; B4DX48 [Other Products]
 UniProt Related Accession #    P23975 [Other Products]
 Molecular Weight    57,370 Da
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 NCBI Official Full Name    norepinephrine transporter
 NCBI Official Synonym Full Names    solute carrier family 6 member 2
 NCBI Official Symbol    SLC6A2 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    sodium-dependent noradrenaline transporter
 UniProt Protein Name    Sodium-dependent noradrenaline transporter
 UniProt Synonym Protein Names   
Norepinephrine transporter; NET; Solute carrier family 6 member 2
 UniProt Gene Name    SLC6A2 [Similar Products]
 UniProt Synonym Gene Names    NAT1; NET1; SLC6A5; NET [Similar Products]
 UniProt Entry Name    SC6A2_HUMAN
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 NCBI Summary for NE    This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
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 UniProt Comments for NE    SLC6A2: Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals. Defects in SLC6A2 are a cause of orthostatic intolerance (OI). OI is a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. It is associated with postural tachycardia. Plasma norepinephrine concentration is abnormally high. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A2 subfamily.

Protein type: Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass; Transporter

Chromosomal Location of Human Ortholog: 16q12.2

Cellular Component: integral to plasma membrane; membrane; neuron projection; plasma membrane

Molecular Function: dopamine:sodium symporter activity; monoamine transmembrane transporter activity; norephinephrine:sodium symporter activity; protein binding

Biological Process: dopamine uptake; monoamine transport; norepinephrine transport; response to pain; synaptic transmission; transmembrane transport; transport

Disease: Orthostatic Intolerance
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 Research Articles on NE    1. This corticotropin releasing factor-induced regulation on norepinephrine transporter expression and function may play a role in development of stress-related depression and anxiety
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with NE elisa kitOrgans/Tissues associated with NE elisa kit
 Products by Pathway  Pathway Diagram
 Monoamine Transport Pathway antibodies  Monoamine Transport Pathway Diagram
 Na+/Cl- Dependent Neurotransmitter Transporters Pathway antibodies  Na+/Cl- Dependent Neurotransmitter Transporters Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies  Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >290 publications with NE and Brain
 Nerve Antibodies  >268 publications with NE and Nerve
 Muscle Antibodies  >45 publications with NE and Muscle
 Kidney Antibodies  >28 publications with NE and Kidney
 Placenta Antibodies  >19 publications with NE and Placenta
 Intestine Antibodies  >3 publications with NE and Intestine
 Testis Antibodies  >2 publications with NE and Testis
 Prostate Antibodies  >1 publications with NE and Prostate
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