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OCLN elisa kit :: Mouse Occludin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS033432 OCLN elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Occludin (OCLN), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Occludin ELISA Kit

 Product Gene Name   

OCLN elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 5; NC_000005.9 (68788119..68853931). Location: 5q13.1
 OMIM    251290
 3D Structure    ModBase 3D Structure for Q16625
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 Species Reactivity    Mouse
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
 Assay Type    Sandwich
 Detection Range    31.2ng/ml-1000ng/ml.
 Sensitivity    5.0ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of OCLN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for OCLN purchase    MBS033432 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Occludin (OCLN) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.2ng/ml-1000ng/ml in biological research samples containing OCLN, with an estimated sensitivity of 5.0ng/ml. The ELISA analytical biochemical technique of the MBS033432 kit is based on OCLN antibody-OCLN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect OCLN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, OCLN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for OCLN elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of OCLN (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS033432. Click to request current manual
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NCBI/Uniprot data below describe general gene information for OCLN. It may not necessarily be applicable to this product.
 NCBI GI #    327478416
 NCBI GeneID    100506658
 NCBI Accession #    NP_001192184.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001205255.1 [Other Products]
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 UniProt Primary Accession #    Q16625 [Other Products]
 UniProt Secondary Accession #    Q5U1V4; Q8N6K1; B5BU70; D2DU64; D2DU65; D2IGC0; D2IGC1; E2CYV9 [Other Products]
 UniProt Related Accession #    Q16625 [Other Products]
 Molecular Weight    59,144 Da
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 NCBI Official Full Name    occludin isoform b
 NCBI Official Synonym Full Names    occludin
 NCBI Official Symbol    OCLN [Similar Products]
 NCBI Official Synonym Symbols   
BLCPMG
[Similar Products]
 NCBI Protein Information    occludin; tight junction protein occludin
 UniProt Protein Name    Occludin
 Protein Family    Occludin
 UniProt Gene Name    OCLN [Similar Products]
 UniProt Entry Name    OCLN_HUMAN
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 NCBI Summary for OCLN    This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]
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 UniProt Comments for OCLN    occludin: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions. Interacts with TJP1/ZO1 and with VAPA. Localized at tight junctions of both epithelial and endothelial cells. Highly expressed in kidney. Not detected in testis. Belongs to the ELL/occludin family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 5q13.1

Cellular Component: tight junction; apicolateral plasma membrane; endocytic vesicle; apical plasma membrane; integral to membrane; plasma membrane; intercellular junction; cytoplasmic vesicle; cytosol; cell junction

Molecular Function: thiopurine S-methyltransferase activity; protein domain specific binding; protein binding; structural molecule activity

Biological Process: methylation; intercellular junction assembly and maintenance; apoptosis; S-adenosylmethionine metabolic process; S-adenosylhomocysteine metabolic process; protein complex assembly; cell structure disassembly during apoptosis

Disease: Band-like Calcification With Simplified Gyration And Polymicrogyria
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 Research Articles on OCLN    1. Loss of occludin is involved in adhesion, apoptosis, differentiation, Ca2+-homeostasis and neoplastic transformation in UV-exposed human keratinocytes and in skin neoplasms.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with OCLN elisa kitPathways associated with OCLN elisa kit
 Reference Product  PubMed Publications
 TJP1 elisa kit  >503 publications with OCLN and TJP1
 CLDN1 elisa kit  >259 publications with OCLN and CLDN1
 CLDN5 elisa kit  >124 publications with OCLN and CLDN5
 CLDN4 elisa kit  >61 publications with OCLN and CLDN4
 TJP2 elisa kit  >48 publications with OCLN and TJP2
 CLDN3 elisa kit  >47 publications with OCLN and CLDN3
 CLDN7 elisa kit  >16 publications with OCLN and CLDN7
 TJP3 elisa kit  >12 publications with OCLN and TJP3
 CGN elisa kit  >7 publications with OCLN and CGN
 YES1 elisa kit  >1 publications with OCLN and YES1
 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
 TGF-beta Receptor Signaling Pathway antibodies  TGF-beta Receptor Signaling Pathway Diagram
Diseases associated with OCLN elisa kitOrgans/Tissues associated with OCLN elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >132 publications with OCLN and Inflammation
 Nervous System Diseases Antibodies  >130 publications with OCLN and Nervous System Diseases
 Disease Models, Animal Antibodies  >106 publications with OCLN and Disease Models, Animal
 Neoplasms Antibodies  >98 publications with OCLN and Neoplasms
 Necrosis Antibodies  >77 publications with OCLN and Necrosis
 Cardiovascular Diseases Antibodies  >72 publications with OCLN and Cardiovascular Diseases
 Edema Antibodies  >58 publications with OCLN and Edema
 Drug Toxicity Antibodies  >50 publications with OCLN and Drug Toxicity
 Hepatitis Antibodies  >34 publications with OCLN and Hepatitis
 Liver Diseases Antibodies  >34 publications with OCLN and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >255 publications with OCLN and Brain
 Intestine Antibodies  >208 publications with OCLN and Intestine
 Liver Antibodies  >112 publications with OCLN and Liver
 Eye Antibodies  >94 publications with OCLN and Eye
 Kidney Antibodies  >65 publications with OCLN and Kidney
 Testis Antibodies  >54 publications with OCLN and Testis
 Embryonic Tissue Antibodies  >49 publications with OCLN and Embryonic Tissue
 Lung Antibodies  >44 publications with OCLN and Lung
 Stomach Antibodies  >17 publications with OCLN and Stomach
 Pancreas Antibodies  >14 publications with OCLN and Pancreas
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