NP_001517.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
50,694 Da
NCBI Official Full Name
orexin receptor type 2
NCBI Official Synonym Full Names
hypocretin (orexin) receptor 2
NCBI Official Synonym Symbols
NCBI Protein Information
orexin receptor type 2; ox2-R; ox-2-R; orexin type-2 receptor; hypocretin receptor type 2
UniProt Protein Name
Orexin receptor type 2
UniProt Synonym Protein Names
Hypocretin receptor type 2
UniProt Synonym Gene Names
UniProt Entry Name
OX2R_HUMAN
NCBI Summary for HCRTR2
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. [provided by RefSeq, Jan 2009]
UniProt Comments for HCRTR2
HCRTR2: Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1
Chromosomal Location of Human Ortholog: 6p12
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: neuropeptide receptor activity; orexin receptor activity; peptide hormone binding; peptide binding
Biological Process: synaptic transmission; neuropeptide signaling pathway; circadian sleep/wake cycle process; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); feeding behavior; cellular response to hormone stimulus; regulation of circadian sleep/wake cycle, sleep
Research Articles on HCRTR2
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Products associated with HCRTR2 elisa kit
Pathways associated with HCRTR2 elisa kit
Diseases associated with HCRTR2 elisa kit
Organs/Tissues associated with HCRTR2 elisa kit
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