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P-Sel elisa kit :: Mouse P-Selectin (P-Sel) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS266482 P-Sel elisa kit
Unit / Price
48-Strip-Wells  /  $275 +1 FREE 8GB USB
96-Strip-Wells  /  $435 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,755 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,150 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

P-Selectin (P-Sel), ELISA Kit

★Popular Item★
 Also Known As   

Mouse P-Selectin (P-Sel) ELISA kit

 Product Gene Name   

P-Sel elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    gene+601367
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 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of P-Sel elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for P-Sel purchase    MBS266482 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the P-Selectin (P-Sel) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing P-Sel. The ELISA analytical biochemical technique of the MBS266482 kit is based on P-Sel antibody-P-Sel antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect P-Sel antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, P-Sel. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for P-Sel. It may not necessarily be applicable to this product.
 NCBI GI #    157419154
 NCBI GeneID    6403
 NCBI Accession #    NP_002996.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_003005.3 [Other Products]
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 UniProt Secondary Accession #    Q5R344; Q8IVD1 [Other Products]
 UniProt Related Accession #    P16109 [Other Products]
 Molecular Weight    90,834 Da
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 NCBI Official Full Name    P-selectin
 NCBI Official Synonym Full Names    selectin P (granule membrane protein 140kDa, antigen CD62)
 NCBI Official Symbol    SELP [Similar Products]
 NCBI Official Synonym Symbols   
CD62; GRMP; PSEL; CD62P; GMP140; LECAM3; PADGEM
[Similar Products]
 NCBI Protein Information    P-selectin; GMP-140; granule membrane protein 140; granulocyte membrane protein; CD62 antigen-like family member P; platelet alpha-granule membrane protein; leukocyte-endothelial cell adhesion molecule 3; platelet activation dependent granule-external membrane protein
 UniProt Protein Name    P-selectin
 UniProt Synonym Protein Names   
CD62 antigen-like family member P; Granule membrane protein 140; GMP-140; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; Platelet activation dependent granule-external membrane protein; PADGEM; CD_antigen: CD62P
 UniProt Gene Name    SELP [Similar Products]
 UniProt Synonym Gene Names    GMRP; GRMP; GMP-140; LECAM3; PADGEM [Similar Products]
 UniProt Entry Name    LYAM3_HUMAN
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 NCBI Summary for P-Sel    This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008]
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 UniProt Comments for P-Sel    SELP: Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. Defects in SELP may be a cause of susceptibility to ischemic stroke (ISCHSTR); also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. Belongs to the selectin/LECAM family.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 1q22-q25

Cellular Component: nucleoplasm; extracellular space; platelet alpha granule membrane; integral to plasma membrane; cytoplasm; plasma membrane; platelet dense granule membrane; external side of plasma membrane

Molecular Function: heparin binding; protein binding; lipopolysaccharide binding; glycoprotein binding; glycosphingolipid binding; calcium-dependent protein binding; sialic acid binding; fucose binding

Biological Process: platelet activation; positive regulation of leukocyte migration; response to lipopolysaccharide; defense response to Gram-negative bacterium; heterophilic cell adhesion; positive regulation of phosphoinositide 3-kinase cascade; leukocyte adhesion; platelet degranulation; regulation of integrin activation; inflammatory response; leukocyte tethering or rolling; blood coagulation; cell adhesion; leukocyte migration

Disease: Ige Responsiveness, Atopic
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 Research Articles on P-Sel    1. Individuals who undertake physical activity regularly, benefit from each single physical effort, because of decrease in serum concentration of proinflammatory molecules such as L-selectin and P-selectin.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with P-Sel elisa kitPathways associated with P-Sel elisa kit
 Reference Product  PubMed Publications
 CRP elisa kit  >5 publications with P-Sel and CRP
 SELPLG elisa kit  >5 publications with P-Sel and SELPLG
 ITGAM elisa kit  >3 publications with P-Sel and ITGAM
 STAT6 elisa kit  >2 publications with P-Sel and STAT6
 ITGB2 elisa kit  >1 publications with P-Sel and ITGB2
 CD63 elisa kit  >1 publications with P-Sel and CD63
 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 IL-3 Signaling Pathway antibodies  IL-3 Signaling Pathway Diagram
 IL4-mediated Signaling Events Pathway antibodies  IL4-mediated Signaling Events Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Platelet Activation, Signaling And Aggregation Pathway antibodies  Platelet Activation, Signaling And Aggregation Pathway Diagram
 Platelet Degranulation Pathway antibodies  Platelet Degranulation Pathway Diagram
Diseases associated with P-Sel elisa kitOrgans/Tissues associated with P-Sel elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >52 publications with P-Sel and Cardiovascular Diseases
 Inflammation Antibodies  >29 publications with P-Sel and Inflammation
 Heart Diseases Antibodies  >21 publications with P-Sel and Heart Diseases
 Atherosclerosis Antibodies  >19 publications with P-Sel and Atherosclerosis
 Myocardial Ischemia Antibodies  >19 publications with P-Sel and Myocardial Ischemia
 Coronary Artery Disease Antibodies  >18 publications with P-Sel and Coronary Artery Disease
 Neoplasms Antibodies  >17 publications with P-Sel and Neoplasms
 Thrombosis Antibodies  >12 publications with P-Sel and Thrombosis
 Necrosis Antibodies  >8 publications with P-Sel and Necrosis
 Myocardial Infarction Antibodies  >6 publications with P-Sel and Myocardial Infarction
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >90 publications with P-Sel and Blood
 Vascular Antibodies  >41 publications with P-Sel and Vascular
 Brain Antibodies  >14 publications with P-Sel and Brain
 Lung Antibodies  >10 publications with P-Sel and Lung
 Muscle Antibodies  >8 publications with P-Sel and Muscle
 Kidney Antibodies  >6 publications with P-Sel and Kidney
 Bone Antibodies  >6 publications with P-Sel and Bone
 Nerve Antibodies  >4 publications with P-Sel and Nerve
 Testis Antibodies  >4 publications with P-Sel and Testis
 Connective Tissue Antibodies  >3 publications with P-Sel and Connective Tissue
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