NP_068679.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
91,869 Da
NCBI Official Full Name
P protein
NCBI Official Synonym Full Names
oculocutaneous albinism II
NCBI Protein Information
P protein; pink-eyed dilution protein; melanocyte-specific transporter protein
UniProt Protein Name
P protein
UniProt Synonym Protein Names
Melanocyte-specific transporter protein; Pink-eyed dilution protein
UniProt Synonym Gene Names
UniProt Entry Name
P_MOUSE
UniProt Comments for OCA2
OCA2: a transporer of tyrosine, a precursor for melanin synthesis, within melanocytes. Regulates the pH of melanosomes and melanosome maturation. One of the components of the mammalian pigmentary system. Seems to regulate the postranslational processing of tyrosinase, which catalyzes the limiting reaction in melanin synthesis. May serve as a key control point at which ethnic skin color variation is determined. Major determinant of brown and/or blue eye color. Belongs to the SLC13A transporter family.
Protein type: Transporter; Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: endoplasmic reticulum membrane; membrane; lysosomal membrane; melanosome membrane; integral to membrane; endosome membrane
Biological Process: melanin biosynthetic process; cell proliferation; pigmentation; transport; pigmentation during development; melanocyte differentiation; transmembrane transport; spermatid development
Research Articles on OCA2
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Diseases associated with OCA2 elisa kit
Organs/Tissues associated with OCA2 elisa kit
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