NP_081308.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
27,726 Da
NCBI Official Full Name
parkin coregulated gene protein homolog
NCBI Official Synonym Full Names
PARK2 co-regulated
NCBI Protein Information
parkin coregulated gene protein homolog; PARK2 coregulated gene protein; parkin co-regulated gene protein; hypertension-related protein 1-like protein
UniProt Protein Name
Parkin coregulated gene protein homolog
UniProt Synonym Protein Names
Hypertension-related protein 1-like protein; PARK2 coregulated gene protein
UniProt Entry Name
PACRG_MOUSE
UniProt Comments for PACRG
PACRG: Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Mitochondrial
Cellular Component: neuron projection; mitochondrion; nucleus; cytosol; vesicle; cilium
Molecular Function: G-protein-coupled receptor binding; chaperone binding; heat shock protein binding; ubiquitin protein ligase binding; beta-tubulin binding; Hsp70 protein binding; Hsp90 protein binding; actin binding; alpha-tubulin binding
Biological Process: spermatid development
Research Articles on PACRG
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Diseases associated with PACRG elisa kit
Organs/Tissues associated with PACRG elisa kit
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