CAG33333.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
7,989 Da
NCBI Official Full Name
PKIA
NCBI Official Synonym Full Names
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
NCBI Official Synonym Symbols
NCBI Protein Information
cAMP-dependent protein kinase inhibitor alpha; PKI-alpha; cAMP-dependent protein kinase inhibitor, muscle/brain isoform
UniProt Protein Name
cAMP-dependent protein kinase inhibitor alpha
UniProt Synonym Protein Names
cAMP-dependent protein kinase inhibitor, muscle/brain isoform
UniProt Synonym Gene Names
UniProt Entry Name
IPKA_HUMAN
NCBI Summary for PKIa
The protein encoded by this gene is a member of the cAMP-dependent protein kinase (PKA) inhibitor family. This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
UniProt Comments for PKIa
PKIA: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. Belongs to the PKI family.
Protein type: Inhibitor
Chromosomal Location of Human Ortholog: 8q21.12
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding; cAMP-dependent protein kinase inhibitor activity
Biological Process: regulation of G2/M transition of mitotic cell cycle; negative regulation of protein import into nucleus; negative regulation of transcription from RNA polymerase II promoter
Research Articles on PKIa
Precautions
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Disclaimer
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Pathways associated with PKIa elisa kit
Diseases associated with PKIa elisa kit
Organs/Tissues associated with PKIa elisa kit
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