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PVRL2 elisa kit :: Mouse PVRL2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2510611
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
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 Product Name   

PVRL2, ELISA Kit

★Popular Item★
 Also Known As   

Mouse PVRL2 (Poliovirus Receptor Related Protein 2) ELISA Kit

 Product Gene Name   

PVRL2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    600798
 3D Structure    ModBase 3D Structure for Q92692
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 Species Reactivity    Mouse
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 Specificity    This kit recognizes natural and recombinant Mouse PVRL2. No significant cross-reactivity or interference between Mouse PVRL2 and analogues was observed.
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 Samples    Serum, plasma and other biological fluids
 Assay Type    Sandwich
 Detection Range    78.125-5000pg/mL
 Sensitivity    The minimum detectable dose of Mouse PVRL2 is 46.875pg/mL (The sensitivity of this assay, or lowest detectable limit (LDL) was defined as the lowest protein concentration that could be differentiated from zero).
 Intended Uses    This ELISA kit applies to the in vitro quantitative determination of Mouse PVRL2 concentrations in serum, plasma and other biological fluids.
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PVRL2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PVRL2 purchase    MBS2510611 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the PVRL2, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 78.125-5000pg/mL in biological research samples containing PVRL2, with an estimated sensitivity of The minimum detectable dose of Mouse PVRL2 is 46.875pg/mL (The sensitivity of this assay, or lowest detectable limit (LDL) was defined as the lowest protein concentration that could be differentiated from zero). The ELISA analytical biochemical technique of the MBS2510611 kit is based on PVRL2 antibody-PVRL2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PVRL2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PVRL2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for PVRL2 elisa kit

   Principle of the assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to PVRL2. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for PVRL2 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain PVRL2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of PVRL2. You can calculate the concentration of PVRL2 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of PVRL2 elisa kit    PVRL2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2510611. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PVRL2. It may not necessarily be applicable to this product.
 NCBI GI #    112789532
 NCBI GeneID    5819
 NCBI Accession #    NP_001036189.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001042724.1 [Other Products]
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 UniProt Primary Accession #    Q92692 [Other Products]
 UniProt Secondary Accession #    O75455; Q6IBI6; Q96J29; A8K5L5 [Other Products]
 UniProt Related Accession #    Q92692 [Other Products]
 Molecular Weight    51,359 Da
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 NCBI Official Full Name    nectin-2 isoform delta
 NCBI Official Synonym Full Names    poliovirus receptor-related 2 (herpesvirus entry mediator B)
 NCBI Official Symbol    PVRL2 [Similar Products]
 NCBI Official Synonym Symbols   
HVEB; PRR2; CD112; PVRR2
[Similar Products]
 NCBI Protein Information    nectin-2; herpesvirus entry protein B; poliovirus receptor-like 2
 UniProt Protein Name    Nectin-2
 UniProt Synonym Protein Names   
Herpes virus entry mediator B; Herpesvirus entry mediator B; HveB; Poliovirus receptor-related protein 2; CD_antigen: CD112
 UniProt Gene Name    PVRL2 [Similar Products]
 UniProt Synonym Gene Names    HVEB; PRR2; Herpesvirus entry mediator B; HveB [Similar Products]
 UniProt Entry Name    PVRL2_HUMAN
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 NCBI Summary for PVRL2    This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PVRL2    nectin 2: Probable cell adhesion protein. Belongs to the nectin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: focal adhesion; cell surface; integral to membrane; plasma membrane; intercellular junction; zonula adherens

Molecular Function: viral receptor activity; identical protein binding; protein binding; protein homodimerization activity; coreceptor activity; cell adhesion molecule binding

Biological Process: establishment of mitochondrion localization; acrosome formation; intercellular junction assembly and maintenance; regulation of immune response; sperm mitochondrion organization and biogenesis; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; positive regulation of immunoglobulin mediated immune response; spermatid nuclear differentiation; cytoskeleton organization and biogenesis; susceptibility to natural killer cell mediated cytotoxicity; virion attachment, binding of host cell surface coreceptor; signal transduction; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of mast cell activation; viral envelope fusion with host membrane; fertilization; cell part morphogenesis; adhesion to host; homophilic cell adhesion; spermatid development
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 Research Articles on PVRL2    1. Nectin-3 trans-interacts with Nectin-2 to promote lymphocyte and monocyte extravasation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PVRL2 elisa kitPathways associated with PVRL2 elisa kit
 Reference Product  PubMed Publications
 PVRL1 elisa kit  >14 publications with PVRL2 and PVRL1
 PVRL3 elisa kit  >3 publications with PVRL2 and PVRL3
 CDH2 elisa kit  >2 publications with PVRL2 and CDH2
 CTNNB1 elisa kit  >2 publications with PVRL2 and CTNNB1
 CTNNA1 elisa kit  >1 publications with PVRL2 and CTNNA1
 PVRL4 elisa kit  >1 publications with PVRL2 and PVRL4
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Adherens Junctions Interactions Pathway antibodies  Adherens Junctions Interactions Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Cell-cell Junction Organization Pathway antibodies  Cell-cell Junction Organization Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
Diseases associated with PVRL2 elisa kitOrgans/Tissues associated with PVRL2 elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >5 publications with PVRL2 and Nervous System Diseases
 Adenocarcinoma Antibodies  >2 publications with PVRL2 and Adenocarcinoma
 Carcinoma, Hepatocellular Antibodies  >2 publications with PVRL2 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >2 publications with PVRL2 and Liver Neoplasms
 Liver Diseases Antibodies  >2 publications with PVRL2 and Liver Diseases
 Abnormalities, Multiple Antibodies  >1 publications with PVRL2 and Abnormalities, Multiple
 Heart Diseases Antibodies  >1 publications with PVRL2 and Heart Diseases
 Myocardial Infarction Antibodies  >1 publications with PVRL2 and Myocardial Infarction
 Necrosis Antibodies  >1 publications with PVRL2 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6 publications with PVRL2 and Blood
 Brain Antibodies  >3 publications with PVRL2 and Brain
 Testis Antibodies  >3 publications with PVRL2 and Testis
 Vascular Antibodies  >2 publications with PVRL2 and Vascular
 Liver Antibodies  >2 publications with PVRL2 and Liver
 Bone Marrow Antibodies  >1 publications with PVRL2 and Bone Marrow
 Heart Antibodies  >1 publications with PVRL2 and Heart
 Bone Antibodies  >1 publications with PVRL2 and Bone
 Eye Antibodies  >1 publications with PVRL2 and Eye
 Lung Antibodies  >1 publications with PVRL2 and Lung
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